Lactobacillus casei potentiates induction of oral tolerance in experimental arthritis

Probiotics have been shown to exert beneficial effects on modulation of diverse diseases. However, no information is available for the effect of probiotics in the induction of oral tolerance in autoimmune diseases. The main purpose of this study was to elucidate whether Lactobacillus casei ( L. case...

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Bibliographic Details
Published in:	Molecular immunology Vol. 46; no. 1; pp. 172 - 180
Main Authors:	So, Jae-Seon, Lee, Choong-Gu, Kwon, Ho-Keun, Yi, Hwa-Jung, Chae, Chang-Suk, Park, Jin-A, Hwang, Ki-Chul, Im, Sin-Hyeog
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-11-2008
Subjects:	Administration, Oral Animals Arthritis, Experimental - immunology Arthritis, Experimental - microbiology Cartilage - drug effects Cartilage - pathology CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - immunology Cell Movement - drug effects Cell Proliferation - drug effects Collagen Type II - administration & dosage Collagen Type II - pharmacology Collagen-induced arthritis Down-Regulation - drug effects Female Forkhead Transcription Factors - immunology Foxp3 Immune Tolerance - immunology Immunoglobulin G - immunology Inflammation - immunology Lactobacillus casei Lactobacillus casei - immunology Oral tolerance Probiotics Rats Rats, Inbred Lew Regulatory T cells Rheumatoid arthritis Th1 Cells - cytology Th1 Cells - drug effects Th1 Cells - immunology Type II collagen Up-Regulation - drug effects Probiotics Lactobacillus casei Rheumatoid arthritis Collagen-induced arthritis Type II collagen Foxp3 Regulatory T cells Oral tolerance
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