Screening of factors inducing alveolar type 1 epithelial cells using human pluripotent stem cells

Alveolar type 2 (AT2) epithelial cells are tissue stem cells capable of differentiating into alveolar type 1 (AT1) cells for injury repair and maintenance of lung homeostasis. However, the factors involved in human AT2-to-AT1 cell differentiation are not fully understood. Here, we established SFTPCG...

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Bibliographic Details

Published in:	Stem cell reports Vol. 19; no. 4; pp. 529 - 544
Main Authors:	Ohnishi, Yuko, Masui, Atsushi, Suezawa, Takahiro, Mikawa, Ryuta, Hirai, Toyohiro, Hagiwara, Masatoshi, Gotoh, Shimpei
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 09-04-2024 Elsevier
Subjects:	AKT alveolar epithelial differentiation high-throughput screening iPSC lung regeneration organoid YAP/TAZ alveolar epithelial differentiation YAP/TAZ iPSC high-throughput screening AKT lung regeneration organoid
Online Access:	Get full text
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