Meloxicam pharmacokinetics using nonlinear mixed‐effects modeling in ferrets after single subcutaneous administration

This study was designed to investigate the pharmacokinetics of meloxicam, an oxicam class, nonsteroidal anti‐inflammatory drug (NSAID), in ferrets. We determined the pharmacokinetic properties of a single subcutaneous dose of meloxicam (0.2 mg/kg) in nine male and nine female ferrets. Blood samples...

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Bibliographic Details
Published in:	Journal of veterinary pharmacology and therapeutics Vol. 37; no. 4; pp. 382 - 387
Main Authors:	Chinnadurai, S. K, Messenger, K. M, Papich, M. G, Harms, C. A
Format:	Journal Article
Language:	English
Published:	England Blackwell Science 01-08-2014 Blackwell Publishing Ltd
Subjects:	absorption analgesics Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics blood Female females ferrets Ferrets - blood Ferrets - metabolism gender differences Half-Life high performance liquid chromatography Injections, Subcutaneous Male males meloxicam nonsteroidal anti-inflammatory agents pharmacokinetics Sex Factors subcutaneous injection syringes Thiazines - administration & dosage Thiazines - pharmacokinetics Thiazoles - administration & dosage Thiazoles - pharmacokinetics vena cava
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