Identification and characterization of peptide drugs in unknown pharmaceutical preparations seized by the Belgian authorities: case report on AOD9604

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Published in:	Drug testing and analysis Vol. 6; no. 9; pp. 964 - 968
Main Authors:	Vanhee, Celine, Moens, Goedele, Deconinck, Eric, De Beer, Jacques O.
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-09-2014 Wiley Subscription Services, Inc
Subjects:	Belgium Chromatography, Liquid Counterfeit Drugs - analysis Drug and Narcotic Control Electrophoresis, Polyacrylamide Gel Peptide Fragments - analysis Peptides - analysis Pharmaceutical Preparations - chemistry Somatostatin - analysis Tandem Mass Spectrometry Belgium
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Author	Moens, Goedele De Beer, Jacques O. Deconinck, Eric Vanhee, Celine
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Cites_doi	10.1111/j.1462-5822.2007.00901.x 10.1016/j.jpba.2014.05.020 10.1002/dta.233 10.1002/dta.1655 10.1016/j.medmal.2012.04.007 10.1210/en.142.12.5182 10.1038/sj.ijo.0801740 10.1007/s00216-011-4702-3 10.1002/dta.1557 10.1057/jphp.2012.53 10.1016/j.jpba.2008.06.016
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References_xml	– volume: 25 start-page: 1442 year: 2001 article-title: Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C‐terminal fragment publication-title: Int. J. Obes. Relat. Metab. Disord. – volume: 34 start-page: 22 year: 2013 article-title: When falsified medicines enter the supply chain: Description of an incident in Kenya and lessons learned for rapid response publication-title: J. Public Health Policy – volume: 227 start-page: 680 year: 1970 article-title: Cleavage of structural proteins during the assembly of the head of bacteriophage T4 publication-title: Nature – volume: 3 start-page: 7 year: 2013 article-title: Safety and tolerability of the hexadecapeptide AOD9604 in humans publication-title: J. Endocrinol. Metab. – volume: 401 start-page: 507 year: 2011 article-title: Determination of growth hormone releasing peptides (GHRP) and their major metabolites in human urine for doping controls by means of liquid chromatography mass spectrometry publication-title: Anal. Bioanal. Chem. – volume: 42 start-page: 247 year: 2012 article-title: Update on counterfeit antibiotics worldwide; public health risks publication-title: Med. Mal. Infect. – volume: 48 start-page: 672 year: 2008 article-title: Determination of oxytocin in a dilute IV solution by LC‐MS(n) publication-title: J. Pharmaceut. Biomed. – volume: 22 start-page: 6 year: 2007 article-title: Medicines informal market in Congo, Burundi and Angola: Counterfeit and substandard antimalarials publication-title: Malar. J. – volume: 5 start-page: 850 year: 2013 article-title: AOD9604 does not influence the WADA hGH isofrom immunoassay publication-title: Drug Test. Anal. – volume: 142 start-page: 5182 year: 2001 article-title: The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)‐AR knock‐out mice publication-title: Endocrinology – year: 2014 article-title: Analytical approaches for the detection of emerging therapeutics and non‐approved drugs in human doping controls publication-title: J. Pharmaceut. Biomed. – volume: 2 start-page: 647 year: 2010 article-title: Identification of CJC‐1295, a growth‐hormone‐releasing peptide, in an unknown pharmaceutical preparation publication-title: Drug Test. Anal. – year: 2013 – year: 2014 article-title: Identification and characterization by LC‐UV‐MS/MS of melanotan II skin‐tanning products sold illegally on the Internet publication-title: Drug Test. Anal. – volume: 3 start-page: 7 year: 2013 ident: e_1_2_4_14_1 article-title: Safety and tolerability of the hexadecapeptide AOD9604 in humans publication-title: J. Endocrinol. Metab. contributor: fullname: Stier H. – ident: e_1_2_4_15_1 doi: 10.1111/j.1462-5822.2007.00901.x – ident: e_1_2_4_8_1 doi: 10.1016/j.jpba.2014.05.020 – volume: 22 start-page: 6 year: 2007 ident: e_1_2_4_4_1 article-title: Medicines informal market in Congo, Burundi and Angola: Counterfeit and substandard antimalarials publication-title: Malar. J. contributor: fullname: Gaudiano M.C. – ident: e_1_2_4_7_1 doi: 10.1002/dta.233 – ident: e_1_2_4_5_1 – ident: e_1_2_4_18_1 doi: 10.1002/dta.1655 – ident: e_1_2_4_2_1 doi: 10.1016/j.medmal.2012.04.007 – ident: e_1_2_4_12_1 doi: 10.1210/en.142.12.5182 – ident: e_1_2_4_9_1 – ident: e_1_2_4_13_1 doi: 10.1038/sj.ijo.0801740 – ident: e_1_2_4_16_1 doi: 10.1007/s00216-011-4702-3 – ident: e_1_2_4_10_1 doi: 10.1002/dta.1557 – ident: e_1_2_4_6_1 – ident: e_1_2_4_19_1 – ident: e_1_2_4_3_1 doi: 10.1057/jphp.2012.53 – ident: e_1_2_4_17_1 doi: 10.1016/j.jpba.2008.06.016 – ident: e_1_2_4_11_1
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SubjectTerms	Belgium Chromatography, Liquid Counterfeit Drugs - analysis Drug and Narcotic Control Electrophoresis, Polyacrylamide Gel Peptide Fragments - analysis Peptides - analysis Pharmaceutical Preparations - chemistry Somatostatin - analysis Tandem Mass Spectrometry
Title	Identification and characterization of peptide drugs in unknown pharmaceutical preparations seized by the Belgian authorities: case report on AOD9604
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