Evaluation of visual field parameters in patients with chronic obstructive pulmonary disease

• Published in: Acta ophthalmologica (Oxford, England) Vol. 90; no. 5; pp. e349 - e354
• Main Authors: Demir, Helin Deniz, İnönü, Handan, Kurt, Semiha, Doruk, Sibel, Aydın, Erdinc, Etikan, İlker
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01-08-2012
• Subjects: blue-on-yellow perimetry; Case-Control Studies; chronic obstructive pulmonary disease; Evoked Potentials, Visual - physiology; Female; Forced Expiratory Volume; Humans; Intraocular Pressure; Male; Middle Aged; Optic Nerve - physiopathology; Oxygen - blood; Partial Pressure; Prospective Studies; Pulmonary Disease, Chronic Obstructive - physiopathology; Retina - physiopathology; VEP; visual field; Visual Field Tests; Visual Fields - physiology; Vital Capacity; white-on-white perimetry
• ISSN: 1755-375X; 1755-3768
• DOI: 10.1111/j.1755-3768.2012.02432.x

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Purpose:  To evaluate the effects of chronic obstructive pulmonary disease (COPD) on retina and optic nerve.
Methods:  Thirty‐eight patients with COPD and 29 healthy controls, totally 67 subjects, were included in the study. Visual evoked potentials (VEP) and visual field assessment (both standard achromatic perimetry (SAP) and short‐wavelength automated perimetry (SWAP)) were performed on each subject after ophthalmological, neurological and pulmonary examinations.
Results:  Mean deviation (MD), pattern standard deviation (PSD) and corrected pattern standard deviation (CPSD) were significantly different between patient and control groups as for both SAP and SWAP measurements (p = 0.001, 0.019, 0.009 and p = 0.004,0.019, 0.031, respectively). Short‐term fluctuation (SF) was not statistically different between the study and the control groups (p = 0.874 and 0.694, respectively). VEP P100 latencies were significantly different between patients with COPD and the controls (p = 0.019).
Conclusion:  Chronic obstructive pulmonary disease is a systemic disease, and hypoxia in COPD seems to affect the retina and the optic nerve.