Transgastric large-organ extraction: the initial human experience

• Published in: Surgical endoscopy Vol. 27; no. 2; pp. 394 - 399
• Main Authors: Dotai, Takayuki, Coker, Alisa M., Antozzi, Luciano, Acosta, Geylor, Michelotti, Marcos, Bildzukewicz, Nikolai, Sandler, Bryan J., Jacobsen, Garth R., Talamini, Mark A., Horgan, Santiago
• Format: Journal Article
• Language: English
• Published: New York Springer-Verlag 01-02-2013; Springer Nature B.V
• Subjects: Abdomen; Abdominal Surgery; Adult; Appendectomy; Body mass index; Cholecystectomy; Endoscopy; Feasibility Studies; Female; Gastrectomy - methods; Gastroenterology; Gastrointestinal surgery; Gynecology; Hepatology; Humans; Laparoscopy; Male; Medicine; Medicine & Public Health; Middle Aged; Mouth; Natural Orifice Endoscopic Surgery - methods; Proctology; Retrospective Studies; Review boards; Stomach; Surgery; NOTES; Transoral; Trocar site complication; Transgastric; Sleeve gastrectomy
• ISSN: 0930-2794; 1432-2218
• DOI: 10.1007/s00464-012-2473-3

Introduction
In laparoscopy, it often is the case that port sites are enlarged for specimen extraction. This leads to higher risk of trocar site complications, such as infection or incisional hernia. Natural orifice surgery (NOTES) is beneficial for minimizing these complications, and this is emphasized when the extracted specimen is of large volume. We have been using transgastric technique for appendectomy, cholecystectomy, and laparoscopic sleeve gastrectomy (LSG). Of these transgastric operations, we focus on the one with relatively large-organ extraction: LSG with transoral remnant extraction (TORE). We describe the details and feasibility of this procedure and compare the outcomes to conventional LSG.
Methods
All patients undergoing LSG were considered candidates for TORE and were consented for this procedure if interested after an informed discussion. Eighteen LSGs with TORE (TORE group) and ten conventional LSGs (non-TORE group) were performed from August 2010 to March 2011. We retrospectively compared these two groups for the age, sex, preoperative body mass index, operating room time, hospital stay, excess weight loss (EWL), and trocar site complications. Laparoscopic sleeve gastrectomy with TORE consists of conventional LSG and transgastric retrieval of the resected stomach. The procedure exceeds exactly the same manner as conventional LSG until the initial stapling of the stomach. For TORE, the gastrectomy is initiated 5 cm proximal to the pylorus than usual LSG to save the space for the gastrotomy used for specimen retrieval. After the gastrectomy is completed, the full thickness of the distal most part of the staple line is incised open as wide as 2 cm by using electric cautery or ultrasonic dissector. A flexible upper endoscope, which has been in the stomach already as a bougie for gastrectomy, is then guided into the peritoneal cavity through the gastrotomy. The specimen is grasped endoscopically with a snare and extracted transorally. Following this, the gastrotomy is closed laparoscopically. The final shape of the gastric sleeve is identical to the one of conventional LSG.
Results
There was no significant difference between the TORE and the non-TORE group for patients’ profile, operating room time, hospital stay, and EWL. Neither group has experienced perioperative complications. All specimens were extracted readily and safely in the TORE group. Of the ten cases in the non-TORE group, four required extension of the trocar site. No trocar site complications were found in the TORE group, whereas the extended trocar site developed panniculitis in two cases of the non-TORE group; one required panniculectomy for refractory induration.
Conclusions
TORE can be safely and easily performed by surgeons with laparoscopic and endoscopic skill, and with commonly available instruments. While producing identical outcomes, our initial experience with the TORE technique demonstrates an advantage over traditional LSG, because it minimizes trocar site complications. Transgastric organ extraction is potentially applicable to other large-organ extractions in laparoscopic surgery without excessive risk or resources. Larger case volume and longer follow-up period is awaited.