The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions

• Published in: Saudi journal of biological sciences Vol. 28; no. 4; pp. 2041 - 2048
• Main Authors: Imam, Faisal, Sharma, Manju, Obaid Al-Harbi, Naif, Rashid Khan, Mohammad, Qamar, Wajhul, Iqbal, Muzaffar, Daud Ali, Mohammad, Ali, Nemat, Khalid Anwar, Md
• Format: Journal Article
• Language: English
• Published: Saudi Arabia Elsevier B.V 01-04-2021; Elsevier
• Subjects: DOTS; Education; Income; Original; RNTCP; Socioeconomic Status; Tuberculosis; Socioeconomic Status; DOTS; Tuberculosis; Education; RNTCP; Income
• ISSN: 1319-562X; 2213-7106
• DOI: 10.1016/j.sjbs.2021.02.004

•Socio-economic status is very important in patient receiving DOT therapy.•Income influences disease occurrence as well as adverse events.•Occupation increases the risk of diseases and results increase risk of adverse events.•Low income results mal nutrition and increased risk of drug intolerance or adverse events.•DOTS is an effective treatment strategy for MTB patients.
First-line antituberculosis (anti-TB) compounds have been considered as proven components of the Directly Observed Treatment-Short course (DOTS). Drug therapy against tuberculosis has been categorized as I, II, or III following the Revised National Tuberculosis Control Program guidelines. Anti-TB are drugs are quite common and show limited adverse effects. However, first-line anti-TB compounds mediated DOTS therapy and were found with several complications. Thus, those drugs have been discontinued. Therefore, the present study was designed to find out the possible impact of socioeconomic, income, and educational status on the adverse effects of drugs and their therapeutic episodes in patients targeted with a combination of tuberculosis intervention. This study found that an increased incidence of tuberculosis was found in patients who have finished high school, contributing to a high percentage of adverse effects. Notably, adverse events were shown maximally in poor patients compared with rich- or high-income patients. On the contrary, a high prevalence of adverse events was shown to be increased in partially skilled workers compared with full-skilled workers. Consequently, adversely considerable events were implicated to be raised in patients associated with minimal socioeconomic class. Such interesting factors would help in monitoring such events in experimental patients.