Oligo(Lactic Acid)8-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer

Docetaxel (DTX) is among the most frequently prescribed chemotherapy drugs and has recently been shown to extend survival in advanced prostate cancer patients. However, the poor water solubility of DTX prevents full exploitation of this potent anticancer drug. The current marketed formulation, Taxot...

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Bibliographic Details
Published in:	Nanomaterials (Basel, Switzerland) Vol. 11; no. 10; p. 2745
Main Authors:	Repp, Lauren, Unterberger, Christopher J., Ye, Zhengqing, Feltenberger, John B., Swanson, Steven M., Marker, Paul C., Kwon, Glen S.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 17-10-2021 MDPI
Subjects:	Acids Antibodies Antitumor agents Aqueous solutions Biocompatibility Cancer therapies Cell cycle Chemotherapy Degradation docetaxel Drug carriers Drug delivery Esterase In vivo methods and tests Intravenous administration Micelles NMR Nuclear magnetic resonance Polyethylene glycol Polylactic acid polymeric micelle prodrug Prodrugs Prostate cancer Stability Taxotere Tumors United States > US
Online Access:	Get full text
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