Discovery of Long Non-Coding RNA MALAT1 Amplification in Precancerous Colorectal Lesions

A colorectal adenoma, an aberrantly growing tissue, arises from the intestinal epithelium and is considered as precursor of colorectal cancer (CRC). In this study, we investigated structural and numerical chromosomal aberrations in adenomas, hypothesizing that chromosomal instability (CIN) occurs ea...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 23; no. 14; p. 7656
Main Authors:	Siskova, Anna, Kral, Jan, Drabova, Jana, Cervena, Klara, Tomasova, Kristyna, Jungwirth, Jiri, Hucl, Tomas, Kohout, Pavel, Summerova, Sandra, Vodickova, Ludmila, Vodicka, Pavel, Vymetalkova, Veronika
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 11-07-2022 MDPI
Subjects:	Adenoma adenomas array comparative genomic hybridization Chromosome aberrations Chromosomes Collagen (type I) Colorectal cancer Colorectal carcinoma Epigenetics Epithelium Gene amplification Genomic instability Hybridization Karyotypes long non-coding RNA MALAT1 Metastases Mutation Non-coding RNA Tumors
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