Induction of metallothionein synthesis by zinc in cadmium pretreated rats

The ability of zinc (Zn) salts to induce the synthesis of metallothionein (MT) in liver, kidney and pancreas of rats pretreated with cadmium (Cd) salts was investigated. Twenty-four hours after either CdCl2 (2.0 mg Cd/kg, s.c.) or saline pretreatment, rats were injected with saline, CdCl2 (2.0 mg Cd...

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Bibliographic Details
Published in:	Toxicology (Amsterdam) Vol. 63; no. 3; p. 273
Main Authors:	Suzuki, C A, Ohta, H, Albores, A, Koropatnick, J, Cherian, M G
Format:	Journal Article
Language:	English
Published:	Ireland 01-09-1990
Subjects:	Animals Blotting, Northern Cadmium - administration & dosage Cadmium - metabolism Cytosol - metabolism Drug Administration Schedule Gene Expression - drug effects Kidney - metabolism Liver - metabolism Male Metallothionein - biosynthesis Metallothionein - genetics Pancreas - metabolism Rats Rats, Inbred Strains RNA, Messenger - genetics Zinc - administration & dosage Zinc - metabolism
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