Radiation-induced epigenetic alterations after low and high LET irradiations

Epigenetics, including DNA methylation and microRNA (miRNA) expression, could be the missing link in understanding radiation-induced genomic instability (RIGI). This study tests the hypothesis that irradiation induces epigenetic aberrations, which could eventually lead to RIGI, and that the epigenet...

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Bibliographic Details

Published in:	Mutation research Vol. 707; no. 1-2; p. 24
Main Authors:	Aypar, Umut, Morgan, William F, Baulch, Janet E
Format:	Journal Article
Language:	English
Published:	Netherlands 10-02-2011
Subjects:	Animals Cell Line Cell Survival - radiation effects Cricetinae DNA Damage - radiation effects DNA Methylation - radiation effects Dose-Response Relationship, Radiation Epigenesis, Genetic - radiation effects Genomic Instability - radiation effects Humans Ions Iron Linear Energy Transfer MicroRNAs - radiation effects X-Rays
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