Breast cancer bone metastases: pathogenesis and therapeutic targets
Breast cancer is the most common cancer affecting women worldwide, with bone metastases presenting as the most common site of disease recurrence. Bone metastases secondary to breast cancer negatively impacts patient survival, mobility, and quality of life. Furthermore, the clinical complications of...
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| Published in: | The international journal of biochemistry & cell biology Vol. 96; pp. 63 - 78 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
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Elsevier Ltd
01-03-2018
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| Abstract | Breast cancer is the most common cancer affecting women worldwide, with bone metastases presenting as the most common site of disease recurrence. Bone metastases secondary to breast cancer negatively impacts patient survival, mobility, and quality of life. Furthermore, the clinical complications of breast cancer bone metastases are associated with significant financial burden to the individual and society. The molecular mechanisms involved in the metastasis, colonisation, and proliferation of breast cancer cells in bone are complex and involve crosstalk between breast cancer cells and the bone microenvironment. The ability of metastatic breast cancer cells to hijack normal biological processes involved in bone remodelling is a key driver of osteolytic and osteoblastic bone lesions. As such, our understanding of how breast cancer cells manipulate normal bone remodelling pathways is essential for the development of new therapeutic agents to improve patient outcomes. In this review, we discuss bone remodelling under normal physiological conditions and explore key pathways dysregulated in breast cancer metastasis to bone. We provide an overview of systemic therapies currently recommended for the treatment of breast cancer bone metastases and highlight emerging therapeutic targets. |
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| AbstractList | Breast cancer is the most common cancer affecting women worldwide, with bone metastases presenting as the most common site of disease recurrence. Bone metastases secondary to breast cancer negatively impacts patient survival, mobility, and quality of life. Furthermore, the clinical complications of breast cancer bone metastases are associated with significant financial burden to the individual and society. The molecular mechanisms involved in the metastasis, colonisation, and proliferation of breast cancer cells in bone are complex and involve crosstalk between breast cancer cells and the bone microenvironment. The ability of metastatic breast cancer cells to hijack normal biological processes involved in bone remodelling is a key driver of osteolytic and osteoblastic bone lesions. As such, our understanding of how breast cancer cells manipulate normal bone remodelling pathways is essential for the development of new therapeutic agents to improve patient outcomes. In this review, we discuss bone remodelling under normal physiological conditions and explore key pathways dysregulated in breast cancer metastasis to bone. We provide an overview of systemic therapies currently recommended for the treatment of breast cancer bone metastases and highlight emerging therapeutic targets. |
| Author | Dass, Crispin R. Dharmarajan, Arun Brook, Naomi Brook, Emily Chan, Arlene |
| Author_xml | – sequence: 1 givenname: Naomi surname: Brook fullname: Brook, Naomi organization: School of Pharmacy and Biomedical Science, Curtin University, Bentley 6102, Australia – sequence: 2 givenname: Emily surname: Brook fullname: Brook, Emily organization: School of Pharmacy and Biomedical Science, Curtin University, Bentley 6102, Australia – sequence: 3 givenname: Arun surname: Dharmarajan fullname: Dharmarajan, Arun organization: School of Pharmacy and Biomedical Science, Curtin University, Bentley 6102, Australia – sequence: 4 givenname: Crispin R. surname: Dass fullname: Dass, Crispin R. organization: School of Pharmacy and Biomedical Science, Curtin University, Bentley 6102, Australia – sequence: 5 givenname: Arlene surname: Chan fullname: Chan, Arlene email: arlenechan@me.com organization: School of Medicine, Curtin University, Bentley 6102, Australia |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29309917$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.cmet.2006.05.012 10.1124/mol.61.5.1255 10.1038/nm.1979 10.1084/jem.190.12.1741 10.1371/journal.pone.0062936 10.1210/endo.140.10.7034 10.1038/nm.1943 10.1002/jbmr.2485 10.1080/01635581.2016.1213868 10.1158/0008-5472.CAN-09-3251 10.1158/0008-5472.CAN-08-1078 10.1016/S0959-8049(00)00363-4 10.1038/345442a0 10.1158/1078-0432.306.11.1 10.1096/fasebj.4.12.2168326 10.1371/journal.pone.0006896 10.1186/1471-2407-11-29 10.1056/NEJM199004193221603 10.1038/nm1096-1132 10.1046/j.1523-1755.2003.00071.x 10.1172/JCI28568 10.1007/PL00008242 10.1002/(SICI)1097-0142(20000301)88:5<1082::AID-CNCR20>3.0.CO;2-Z 10.1359/jbmr.070401 10.1371/journal.pone.0037624 10.18632/oncotarget.14048 10.18632/oncotarget.15803 10.1016/j.jsbmb.2010.03.048 10.1200/JCO.2005.05.116 10.1038/36593 10.3111/13696998.2014.890937 10.1016/j.cmet.2010.05.005 10.1002/cncr.20308 10.1038/35065016 10.1083/jcb.200409115 10.1158/1541-7786.MCR-16-0081 10.1002/(SICI)1097-4644(19990201)72:2<251::AID-JCB9>3.0.CO;2-W 10.1158/0008-5472.CAN-06-2490 10.1016/S0092-8674(00)80257-3 10.1172/JCI0215234 10.1038/nm.2793 10.1002/ijc.23625 10.1016/S1534-5807(02)00369-6 10.1074/jbc.M111.292946 10.2353/ajpath.2009.080906 10.1016/S8756-3282(98)00138-0 10.1016/j.jbo.2013.09.001 10.1158/0008-5472.CAN-05-1631 10.1158/0008-5472.CAN-09-2758 10.1073/pnas.0805133106 10.1681/ASN.V1261164 10.1073/pnas.95.7.3597 10.1016/j.gene.2004.08.009 10.1023/A:1026404227624 10.1210/me.2006-0346 10.1038/onc.2010.543 10.1111/cas.12309 10.1371/journal.pone.0002942 10.1006/dbio.1998.9197 10.1128/MCB.25.19.8581-8591.2005 10.1002/jbmr.1820 10.1002/(SICI)1097-0142(19971015)80:8+<1572::AID-CNCR7>3.0.CO;2-M 10.1371/journal.pone.0029862 10.3892/ol.2016.5236 10.1242/jcs.110.15.1767 10.1158/0008-5472.CAN-06-4499 10.1371/journal.pone.0066752 10.1093/jn/125.suppl_7.2028S 10.1074/jbc.271.4.2126 10.1016/S0092-8674(01)00622-5 10.1002/jbmr.5650100416 10.1359/jbmr.060714 10.1200/JCO.2010.29.7101 10.1016/j.bone.2005.10.003 10.1359/jbmr.1998.13.4.581 10.1056/NEJM199610033351403 10.1002/ijc.29210 10.1074/jbc.M611781200 10.1016/j.joms.2005.07.010 10.1056/NEJM199612123352401 10.1210/me.2007-0363 10.1200/JCO.1998.16.6.2038 10.1186/s13058-014-0458-y 10.1158/0008-5472.CAN-06-3940 10.1006/bbrc.1998.9788 10.1126/science.1074935 10.3816/CBC.2010.n.059 10.1053/ctrv.2000.0210 10.1073/pnas.1830978100 10.1172/JCI46134 10.1007/s10549-008-9900-0 10.1074/jbc.M302436200 10.1074/jbc.M202561200 10.1038/386081a0 10.1016/j.bone.2010.10.044 10.1158/1541-7786.MCR-07-0119 10.1186/bcr3047 10.1158/0008-5472.CAN-11-3061 10.1083/jcb.99.6.1901 10.1359/jbmr.060820 10.1242/jcs.02655 10.1007/s00520-014-2525-4 10.4248/BR201301003 10.1371/journal.pone.0039871 10.1046/j.1469-7580.1997.19110039.x 10.1111/j.1469-7580.2009.01158.x 10.1083/jcb.41.1.59 10.1158/0008-5472.CAN-05-3565 10.18632/oncotarget.12939 10.1016/S0006-291X(02)02937-6 10.1016/0169-6009(89)90048-2 10.1002/jcp.1072 10.1016/j.devcel.2005.03.016 10.1158/0008-5472.CAN-09-3194 10.3389/fphys.2016.00280 10.2353/ajpath.2008.080243 10.1016/j.bone.2011.06.014 10.1371/journal.pone.0027090 10.1530/ERC-13-0158 10.1371/journal.pone.0003537 10.1111/j.1600-0463.2011.02864.x 10.1210/endo.140.10.7037 10.1359/jbmr.080706 10.1200/JCO.2010.32.5209 10.1242/dev.128.8.1253 10.1023/A:1022943127689 10.1016/j.febslet.2009.06.047 10.1359/jbmr.2001.16.8.1486 10.1359/JBMR.040305 10.1073/pnas.0401602101 10.1016/j.cell.2006.05.012 10.1016/S0021-9258(18)47310-3 10.1172/JCI11296 10.1172/JCI3212 10.1158/0008-5472.CAN-09-4092 10.3892/ol.2011.487 10.1002/jcb.10567 10.3892/ijo.33.1.17 10.1016/j.bbrc.2009.07.029 10.1038/332411a0 10.1016/j.yexcr.2008.02.006 10.1016/S0092-8674(00)80258-5 10.1016/j.bbamcr.2013.12.015 10.1200/JCO.2007.11.8604 10.1158/0008-5472.CAN-07-1046 10.1002/jcb.22211 10.1038/nm.2489 10.1158/1078-0432.CCR-15-2845 10.1677/erc.1.01307 10.1038/nature07713 10.1046/j.1468-1331.1998.560587.x 10.1172/JCI3523 10.1016/j.gene.2005.12.012 10.1007/s00441-010-1086-1 10.4143/crt.2011.43.2.89 10.1084/jem.190.2.293 10.1042/bj3030303 10.1016/j.ccr.2009.05.017 10.1002/cncr.11129 10.1172/JCI26772 10.1016/S0140-6736(15)60995-3 10.1172/JCI118947 10.1158/1535-7163.MCT-14-0253 10.1016/j.canep.2014.05.005 10.1073/pnas.67.3.1513 10.1172/JCI19872 10.1016/j.yexcr.2009.03.003 10.1172/JCI40568 10.1038/sj.bjc.6601397 10.1002/ijc.21865 10.1359/JBMR.051204 10.1002/jcp.1041570312 10.1002/(SICI)1097-0142(19971015)80:8+<1588::AID-CNCR9>3.0.CO;2-G 10.1177/0022034510397196 10.1038/bjc.1998.52 10.1007/s10549-016-3911-z 10.1016/j.bone.2007.02.024 10.3892/mmr.2016.5374 10.1016/j.cell.2013.07.036 10.1186/ar2391 10.1074/jbc.M114.621219 10.1074/jbc.M111.294595 10.1172/JCI117370 10.1124/jpet.106.102004 10.18632/oncotarget.12593 10.1111/cas.13081 10.1016/j.bbrc.2013.12.036 10.1016/S8756-3282(02)00847-5 10.1016/S0140-6736(15)60908-4 10.1186/s13058-015-0537-8 10.1073/pnas.130200197 10.1074/jbc.M111.244236 10.1006/excr.1995.1005 10.1084/jem.156.6.1604 10.1038/sj.onc.1209552 10.1210/edrv.23.3.0465 10.1016/S0092-8674(01)00206-9 10.1016/S1470-2045(14)70302-X 10.1016/S1535-6108(03)00132-6 10.1200/JCO.2008.19.2146 10.1210/endo-119-4-1776 10.1210/me.2007-0237 10.1186/bcr3616 10.1002/ijc.24780 10.1038/leu.2012.17 10.1007/BF02556671 10.1056/NEJM199508103330607 10.1158/0008-5472.CAN-15-2614 10.1038/sj.onc.1210154 10.1093/annonc/mdg367 10.1007/s12094-014-1247-x 10.1016/j.bbrc.2005.07.092 10.1038/sj.bjc.6602417 10.1007/s00520-016-3154-x 10.1186/s12967-017-1192-x 10.1084/jem.20101474 10.1038/srep32804 10.1186/bcr2781 10.1126/science.8079170 10.1093/emboj/17.15.4456 10.1200/JCO.2008.20.0725 10.1038/sj.emboj.7601430 10.1186/2193-1801-3-328 |
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| References | Sternlicht, Glezerman (bib0980) 2015; 11 Atkins (bib0080) 2007; 40 Barasch (bib0100) 2011; 90 Käkönen (bib0480) 2002; 277 Singh (bib0965) 2007; 26 Lotinun (bib0660) 2013; 123 Lynch (bib0670) 1995; 216 Podgorski (bib0830) 2009; 175 Holland (bib0405) 2006; 66 Jung (bib0475) 2006; 38 DeKoter, Walsh, Singh (bib0275) 1998; 17 Sims (bib0960) 2004; 113 Crotti (bib0255) 2006; 372 De Groen (bib0270) 1996; 335 Minemura (bib0710) 2016; 107 Lee (bib0590) 2009; 387 Lipton (bib0640) 2007; 25 Zhang (bib1205) 2012; 3 Dunford (bib0295) 2001; 296 Ooi (bib0800) 2010; 70 Jayaraman, Doucet, Kominsky (bib0450) 2017; 8 Rucci (bib0885) 2006; 318 Yin (bib1175) 2003; 100 Takayanagi (bib1000) 2002; 3 Hiraga (bib0395) 2012; 72 Zhi (bib1240) 2011; 30 Anderson (bib0035) 1997; 390 Adami (bib0010) 1987; 41 Sutton (bib0990) 2008; 22 BORD (bib0085) 1997; 191 Müller (bib0680) 2001; 410 Chen (bib0200) 2011; 286 Song (bib0970) 2009; 583 Pivetta (bib0825) 2011; 13 Ni (bib0765) 2014; 105 Rose (bib0875) 2007; 5 Anon (bib0055) 2017 Hagiwara, Delea, Chung (bib0380) 2014; 17 Richert (bib0860) 2009; 21 Kornak (bib0530) 2001; 104 Thomas (bib1035) 1999; 140 Yagi (bib1130) 2007; 22 Fang (bib0325) 2012 Kim (bib0500) 2016; 76 Saidak (bib0900) 2009; 315 Shi (bib0945) 2004; 343 Kogawa (bib0515) 2010; 121 Miyama (bib0720) 1999; 208 Bu (bib0150) 2008; 123 Ucer (bib1055) 2015; 30 Markowitz (bib0695) 2003; 64 Lipton (bib0635) 2000; 88 Nannuru (bib0750) 2010; 70 Yin, Li (bib1165) 2006; 116 Yoneda (bib1180) 2001; 16 Chaudhri (bib0190) 2012; 287 Dunn (bib0300) 2009; 4 Jensen (bib0455) 2001; 15 Van Poznak (bib1060) 2011; 29 Gordon (bib0355) 2009; 107 Li (bib0630) 2015; 17 Tamura (bib1010) 2008 Chiu (bib0205) 2017; 15 Coleman (bib0245) 2001; 27 Hortobagyi (bib0410) 1996; 335 Levin (bib0615) 1995; 333 Hofbauer (bib0400) 1999; 140 Cleeland (bib0215) 2016; 24 Keller (bib0490) 2014 Montessuit, Bonjour, Caverzasio (bib0725) 1995; 10 Kohno (bib0520) 2005; 23 Rosen (bib0880) 2004; 100 Shevde (bib0940) 2000; 97 Thiolloy (bib1030) 2012; 7 Zhang (bib1190) 2004; 24 Riggs, Khosla, Melton (bib0865) 2002; 23 Shalhoub (bib0935) 1999; 72 Kousteni (bib0545) 2002; 298 Duivenvoorden, Hirte, Singh (bib0290) 1999; 17 Brömme (bib0135) 1996; 271 Baldock (bib0090) 2006; 21 Nicolaidou (bib0770) 2012; 7 Yee (bib1155) 1993; 157 Barnes (bib0105) 2003; 63 Guise (bib0375) 1997; 80 Littlewood-Evans (bib0645) 1997; 57 Pederson (bib0815) 2008; 105 Xu (bib1125) 2012; 7 Brault (bib0145) 2001; 128 Kuchuk (bib0550) 2013; 2 Zhao (bib1225) 2006; 4 Sanchez-Fernandez (bib0915) 2008; 3 Marx (bib0705) 2005; 63 Clines (bib0220) 2007; 21 Walker (bib1075) 2010; 120 Sasano (bib0920) 2000; 202 Takyar (bib1005) 2013; 28 Kitten, Andrews (bib0510) 2001; 187 Peng (bib0820) 2009; 113 Rogers (bib0870) 1994; 303 Maes (bib0685) 2006; 116 Dobreva (bib0280) 2006; 125 Huebner (bib0425) 2006; 21 Toyomura (bib1045) 2003; 278 Yanagisawa (bib1140) 1988; 332 Anon (bib0050) 2016 Ishii (bib0440) 2010; 207 Anon (bib0045) 2015 Llombart (bib0655) 2011 Zhao (bib1230) 2007; 67 Li (bib0620) 2007; 282 Duong (bib0310) 2014; 13 Ferlay (bib0330) 2015; 136 Martínez-Herrero (bib0700) 2016; 7 Winkler (bib1095) 2012; 26 Ali, Sajdera, Anderson (bib0030) 1970; 67 Gnant (bib0345) 2015; 386 Wilmanski (bib1085) 2016; 68 Kwon (bib0555) 2005; 335 Palokangas, Mulari, Vaananen (bib0805) 1997; 110 Arsenault (bib0075) 1989; 6 Body (bib0130) 2003; 14 Negishi-Koga (bib0755) 2011; 17 Patrick (bib0810) 2015; 23 Yi (bib1160) 2002; 62 Ryu (bib0895) 2006; 25 Bundred, Walls, Ratcliffe (bib0160) 1996; 78 Burger, Van der Meer, Nijweide (bib0170) 1984; 99 Chen, Sosnoski, Mastro (bib0195) 2010; 12 Guise, Yin, Mohammad (bib0370) 2003; 97 Tondravi (bib1040) 1997; 386 Huang (bib0420) 1994; 94 Simonson, Dunn (bib0955) 1990; 4 Bandyopadhyay (bib0095) 2006; 66 Rucci (bib0890) 2010; 70 Samee (bib0910) 2008; 173 Harries (bib0385) 2014; 38 Markowitz (bib0690) 2001; 12 Oehler (bib0790) 2003; 89 Zheng (bib1235) 2007; 67 Kitazawa (bib0505) 2003; 89 Muraoka (bib0730) 2002; 109 Komori (bib0525) 1997; 89 Lee (bib0585) 2005; 169 O'Brien (bib0785) 2008; 3 Fowlkes (bib0340) 1994; 269 Tang (bib1025) 2011; 286 Chou (bib0210) 2006; 25 Taipaleenmäki (bib0995) 2016; 7 Tang (bib1020) 2009; 15 Biswas (bib0125) 2011; 6 E.B.C.T.C. Group (bib0315) 2015; 386 Day (bib0265) 2005; 8 Xu, Teitelbaum (bib1120) 2013; 1 Neve, Corrado, Cantatore (bib0760) 2011; 343 Lee (bib0595) 2011; 43 Walker (bib1070) 2008; 23 Arai (bib0070) 1999; 190 Campbell (bib0185) 1992; 130 Myoui (bib0735) 2003; 63 Anon (bib0065) 2017 Goss (bib0360) 2013; 31 Pratap (bib0845) 2008; 68 Hughes (bib0430) 1996; 2 Niida (bib0775) 1999; 190 Buijs (bib0155) 2007; 67 Nakagawa (bib0740) 1998; 253 Fizazi (bib0335) 2009; 27 Luckman (bib0665) 1998; 13 Burtis (bib0175) 1990; 322 Mócsai (bib0675) 2004; 101 Lüftner (bib0560) 2014; 3 Scott (bib0930) 1994; 265 Stern (bib0975) 1995; 125 Mitri (bib0715) 2016; 22 Bekker (bib0110) 2004; 19 Kousteni (bib0540) 2001; 104 Rauch (bib0855) 2010; 11 Le Gall (bib0575) 2007; 67 Bendinelli (bib0115) 2014; 1843 Jayaraman (bib0445) 2016; 14 Brama (bib0140) 2007; 14 Aklilu (bib0020) 2011; 48 Lau (bib0570) 2013; 8 Kang (bib0485) 2003; 3 Abdelmagid (bib0005) 2008; 314 Nakashima (bib0745) 2002; 108 Lev (bib0610) 2005; 11 Wang (bib1080) 2013; 8 Fang, Xu (bib0320) 2015; 17 Zhang (bib1200) 2009; 16 Helweg-Larsen, Laursen (bib0390) 1998; 5 Ohshiba, Miyaura, Ito (bib0795) 2003; 300 Duong (bib0305) 1998; 102 Calvi (bib0180) 2001; 107 Vukmirovic-Popovic (bib1065) 2002; 31 Anon (bib0060) 2017 Coleman (bib0235) 2014; 15 Zhang (bib1195) 2008; 10 Tan (bib1015) 2016; 7 Li (bib0625) 2011; 121 Coenegrachts (bib0225) 2010; 70 Kim (bib0495) 2008; 22 Coleman (bib0240) 1997; 80 Guise (bib0365) 1996; 98 Coltrera (bib0250) 1995; 55 Jensen (bib0465) 2011; 11 Leung (bib0605) 2011; 49 Anderson (bib0040) 1969; 41 Jensen (bib0470) 2014; 443 Wong, Stockler, Pavlakis (bib1100) 2012 Xian (bib1110) 2012; 18 Lau (bib0565) 2010; 126 Yamaza (bib1135) 1998; 23 Stopeck (bib0985) 2010; 28 Hortobagyi (bib0415) 1998; 16 Coleman, Smith, Rubens (bib0230) 1998; 77 Yin (bib1170) 1999; 103 Zhao, Väänänen (bib1220) 2006; 21 Burger (bib0165) 1982; 156 Saidak (bib0905) 2015; 290 Nutter (bib0780) 2014; 21 Xin (bib1115) 2016; 6 Korpal (bib0535) 2009; 15 Rachner (bib0850) 2014; 16 Lehenkari (bib0600) 2002; 61 Yoshida (bib1185) 1990; 345 Aklilu (bib0015) 2011; 48 Aldridge (bib0025) 2005; 92 Jensen (bib0460) 2010; 10 Ducy (bib0285) 1997; 89 Yasuda (bib1150) 1998; 95 Liu (bib0650) 2016; 14 Siclari (bib0950) 2014; 16 Zhang (bib1210) 2012; 120 Goodwin (bib0350) 2009; 27 Pratap (bib0840) 2005; 25 Yaroslavskiy (bib1145) 2005; 118 Trivedi (bib1050) 2017; 8 Cruzoé-Souza, Sasso-Cerri, Cerri (bib0260) 2009; 215 Pohlodek (bib0835) 2016; 12 Winding (bib1090) 2003; 78 Beresford, Gallagher, Russell (bib0120) 1986; 119 Ishii (bib0435) 2009; 458 Lee (bib0580) 2001; 37 Schott (bib0925) 2016; 159 Wu (bib1105) 2006; 119 Zhang (bib1215) 2013; 154 Clines (10.1016/j.biocel.2018.01.003_bib0220) 2007; 21 Biswas (10.1016/j.biocel.2018.01.003_bib0125) 2011; 6 Zheng (10.1016/j.biocel.2018.01.003_bib1235) 2007; 67 Guise (10.1016/j.biocel.2018.01.003_bib0370) 2003; 97 Myoui (10.1016/j.biocel.2018.01.003_bib0735) 2003; 63 Huebner (10.1016/j.biocel.2018.01.003_bib0425) 2006; 21 Käkönen (10.1016/j.biocel.2018.01.003_bib0480) 2002; 277 Sternlicht (10.1016/j.biocel.2018.01.003_bib0980) 2015; 11 Li (10.1016/j.biocel.2018.01.003_bib0625) 2011; 121 Maes (10.1016/j.biocel.2018.01.003_bib0685) 2006; 116 Montessuit (10.1016/j.biocel.2018.01.003_bib0725) 1995; 10 Zhang (10.1016/j.biocel.2018.01.003_bib1195) 2008; 10 Simonson (10.1016/j.biocel.2018.01.003_bib0955) 1990; 4 Jung (10.1016/j.biocel.2018.01.003_bib0475) 2006; 38 Holland (10.1016/j.biocel.2018.01.003_bib0405) 2006; 66 O'Brien (10.1016/j.biocel.2018.01.003_bib0785) 2008; 3 Barnes (10.1016/j.biocel.2018.01.003_bib0105) 2003; 63 Ooi (10.1016/j.biocel.2018.01.003_bib0800) 2010; 70 Rucci (10.1016/j.biocel.2018.01.003_bib0890) 2010; 70 Winkler (10.1016/j.biocel.2018.01.003_bib1095) 2012; 26 Keller (10.1016/j.biocel.2018.01.003_bib0490) 2014 Thomas (10.1016/j.biocel.2018.01.003_bib1035) 1999; 140 Luckman (10.1016/j.biocel.2018.01.003_bib0665) 1998; 13 Tondravi (10.1016/j.biocel.2018.01.003_bib1040) 1997; 386 Kuchuk (10.1016/j.biocel.2018.01.003_bib0550) 2013; 2 Zhang (10.1016/j.biocel.2018.01.003_bib1210) 2012; 120 Niida (10.1016/j.biocel.2018.01.003_bib0775) 1999; 190 Chiu (10.1016/j.biocel.2018.01.003_bib0205) 2017; 15 Lynch (10.1016/j.biocel.2018.01.003_bib0670) 1995; 216 Marx (10.1016/j.biocel.2018.01.003_bib0705) 2005; 63 Coenegrachts (10.1016/j.biocel.2018.01.003_bib0225) 2010; 70 Podgorski (10.1016/j.biocel.2018.01.003_bib0830) 2009; 175 Xu (10.1016/j.biocel.2018.01.003_bib1125) 2012; 7 Thiolloy (10.1016/j.biocel.2018.01.003_bib1030) 2012; 7 Wong (10.1016/j.biocel.2018.01.003_bib1100) 2012 Aldridge (10.1016/j.biocel.2018.01.003_bib0025) 2005; 92 Kwon (10.1016/j.biocel.2018.01.003_bib0555) 2005; 335 Nakashima (10.1016/j.biocel.2018.01.003_bib0745) 2002; 108 Stern (10.1016/j.biocel.2018.01.003_bib0975) 1995; 125 Gnant (10.1016/j.biocel.2018.01.003_bib0345) 2015; 386 Anon (10.1016/j.biocel.2018.01.003_bib0050) 2016 Yin (10.1016/j.biocel.2018.01.003_bib1170) 1999; 103 Aklilu (10.1016/j.biocel.2018.01.003_bib0020) 2011; 48 Duong (10.1016/j.biocel.2018.01.003_bib0310) 2014; 13 Fang (10.1016/j.biocel.2018.01.003_bib0325) 2012 Littlewood-Evans (10.1016/j.biocel.2018.01.003_bib0645) 1997; 57 Yanagisawa (10.1016/j.biocel.2018.01.003_bib1140) 1988; 332 Taipaleenmäki (10.1016/j.biocel.2018.01.003_bib0995) 2016; 7 Ducy (10.1016/j.biocel.2018.01.003_bib0285) 1997; 89 Zhao (10.1016/j.biocel.2018.01.003_bib1225) 2006; 4 Müller (10.1016/j.biocel.2018.01.003_bib0680) 2001; 410 Sims (10.1016/j.biocel.2018.01.003_bib0960) 2004; 113 Aklilu (10.1016/j.biocel.2018.01.003_bib0015) 2011; 48 Hofbauer (10.1016/j.biocel.2018.01.003_bib0400) 1999; 140 Wu (10.1016/j.biocel.2018.01.003_bib1105) 2006; 119 Oehler (10.1016/j.biocel.2018.01.003_bib0790) 2003; 89 Cruzoé-Souza (10.1016/j.biocel.2018.01.003_bib0260) 2009; 215 Pederson (10.1016/j.biocel.2018.01.003_bib0815) 2008; 105 Yaroslavskiy (10.1016/j.biocel.2018.01.003_bib1145) 2005; 118 Buijs (10.1016/j.biocel.2018.01.003_bib0155) 2007; 67 Dunn (10.1016/j.biocel.2018.01.003_bib0300) 2009; 4 Lau (10.1016/j.biocel.2018.01.003_bib0570) 2013; 8 Coleman (10.1016/j.biocel.2018.01.003_bib0240) 1997; 80 Ryu (10.1016/j.biocel.2018.01.003_bib0895) 2006; 25 Chen (10.1016/j.biocel.2018.01.003_bib0200) 2011; 286 Jensen (10.1016/j.biocel.2018.01.003_bib0455) 2001; 15 Duong (10.1016/j.biocel.2018.01.003_bib0305) 1998; 102 Levin (10.1016/j.biocel.2018.01.003_bib0615) 1995; 333 Yamaza (10.1016/j.biocel.2018.01.003_bib1135) 1998; 23 BORD (10.1016/j.biocel.2018.01.003_bib0085) 1997; 191 Goss (10.1016/j.biocel.2018.01.003_bib0360) 2013; 31 Guise (10.1016/j.biocel.2018.01.003_bib0375) 1997; 80 Le Gall (10.1016/j.biocel.2018.01.003_bib0575) 2007; 67 Tan (10.1016/j.biocel.2018.01.003_bib1015) 2016; 7 Baldock (10.1016/j.biocel.2018.01.003_bib0090) 2006; 21 Brömme (10.1016/j.biocel.2018.01.003_bib0135) 1996; 271 Takyar (10.1016/j.biocel.2018.01.003_bib1005) 2013; 28 Kitazawa (10.1016/j.biocel.2018.01.003_bib0505) 2003; 89 E.B.C.T.C. Group (10.1016/j.biocel.2018.01.003_bib0315) 2015; 386 Lipton (10.1016/j.biocel.2018.01.003_bib0640) 2007; 25 Saidak (10.1016/j.biocel.2018.01.003_bib0900) 2009; 315 Lee (10.1016/j.biocel.2018.01.003_bib0585) 2005; 169 Guise (10.1016/j.biocel.2018.01.003_bib0365) 1996; 98 Zhang (10.1016/j.biocel.2018.01.003_bib1215) 2013; 154 Abdelmagid (10.1016/j.biocel.2018.01.003_bib0005) 2008; 314 Kohno (10.1016/j.biocel.2018.01.003_bib0520) 2005; 23 Korpal (10.1016/j.biocel.2018.01.003_bib0535) 2009; 15 Body (10.1016/j.biocel.2018.01.003_bib0130) 2003; 14 Fizazi (10.1016/j.biocel.2018.01.003_bib0335) 2009; 27 Shevde (10.1016/j.biocel.2018.01.003_bib0940) 2000; 97 Song (10.1016/j.biocel.2018.01.003_bib0970) 2009; 583 Brault (10.1016/j.biocel.2018.01.003_bib0145) 2001; 128 Rachner (10.1016/j.biocel.2018.01.003_bib0850) 2014; 16 Rosen (10.1016/j.biocel.2018.01.003_bib0880) 2004; 100 DeKoter (10.1016/j.biocel.2018.01.003_bib0275) 1998; 17 Walker (10.1016/j.biocel.2018.01.003_bib1070) 2008; 23 Nakagawa (10.1016/j.biocel.2018.01.003_bib0740) 1998; 253 Nutter (10.1016/j.biocel.2018.01.003_bib0780) 2014; 21 Lotinun (10.1016/j.biocel.2018.01.003_bib0660) 2013; 123 Yin (10.1016/j.biocel.2018.01.003_bib1165) 2006; 116 Anon (10.1016/j.biocel.2018.01.003_bib0065) 2017 Llombart (10.1016/j.biocel.2018.01.003_bib0655) 2011 Tamura (10.1016/j.biocel.2018.01.003_bib1010) 2008 Helweg-Larsen (10.1016/j.biocel.2018.01.003_bib0390) 1998; 5 Patrick (10.1016/j.biocel.2018.01.003_bib0810) 2015; 23 Yin (10.1016/j.biocel.2018.01.003_bib1175) 2003; 100 Martínez-Herrero (10.1016/j.biocel.2018.01.003_bib0700) 2016; 7 Bekker (10.1016/j.biocel.2018.01.003_bib0110) 2004; 19 Sanchez-Fernandez (10.1016/j.biocel.2018.01.003_bib0915) 2008; 3 Chou (10.1016/j.biocel.2018.01.003_bib0210) 2006; 25 Ferlay (10.1016/j.biocel.2018.01.003_bib0330) 2015; 136 Ishii (10.1016/j.biocel.2018.01.003_bib0435) 2009; 458 Hiraga (10.1016/j.biocel.2018.01.003_bib0395) 2012; 72 Wang (10.1016/j.biocel.2018.01.003_bib1080) 2013; 8 Kogawa (10.1016/j.biocel.2018.01.003_bib0515) 2010; 121 Chen (10.1016/j.biocel.2018.01.003_bib0195) 2010; 12 Chaudhri (10.1016/j.biocel.2018.01.003_bib0190) 2012; 287 Dobreva (10.1016/j.biocel.2018.01.003_bib0280) 2006; 125 Komori (10.1016/j.biocel.2018.01.003_bib0525) 1997; 89 Zhang (10.1016/j.biocel.2018.01.003_bib1205) 2012; 3 Burger (10.1016/j.biocel.2018.01.003_bib0165) 1982; 156 Sasano (10.1016/j.biocel.2018.01.003_bib0920) 2000; 202 Stopeck (10.1016/j.biocel.2018.01.003_bib0985) 2010; 28 Mócsai (10.1016/j.biocel.2018.01.003_bib0675) 2004; 101 Yoneda (10.1016/j.biocel.2018.01.003_bib1180) 2001; 16 Schott (10.1016/j.biocel.2018.01.003_bib0925) 2016; 159 Coleman (10.1016/j.biocel.2018.01.003_bib0245) 2001; 27 Bandyopadhyay (10.1016/j.biocel.2018.01.003_bib0095) 2006; 66 Kornak (10.1016/j.biocel.2018.01.003_bib0530) 2001; 104 Minemura (10.1016/j.biocel.2018.01.003_bib0710) 2016; 107 Zhang (10.1016/j.biocel.2018.01.003_bib1200) 2009; 16 Campbell (10.1016/j.biocel.2018.01.003_bib0185) 1992; 130 Muraoka (10.1016/j.biocel.2018.01.003_bib0730) 2002; 109 Peng (10.1016/j.biocel.2018.01.003_bib0820) 2009; 113 Anon (10.1016/j.biocel.2018.01.003_bib0060) 2017 Ucer (10.1016/j.biocel.2018.01.003_bib1055) 2015; 30 Leung (10.1016/j.biocel.2018.01.003_bib0605) 2011; 49 Toyomura (10.1016/j.biocel.2018.01.003_bib1045) 2003; 278 Fowlkes (10.1016/j.biocel.2018.01.003_bib0340) 1994; 269 Pohlodek (10.1016/j.biocel.2018.01.003_bib0835) 2016; 12 Burger (10.1016/j.biocel.2018.01.003_bib0170) 1984; 99 Kim (10.1016/j.biocel.2018.01.003_bib0500) 2016; 76 Rose (10.1016/j.biocel.2018.01.003_bib0875) 2007; 5 Yee (10.1016/j.biocel.2018.01.003_bib1155) 1993; 157 Kim (10.1016/j.biocel.2018.01.003_bib0495) 2008; 22 Kitten (10.1016/j.biocel.2018.01.003_bib0510) 2001; 187 Burtis (10.1016/j.biocel.2018.01.003_bib0175) 1990; 322 Tang (10.1016/j.biocel.2018.01.003_bib1020) 2009; 15 Zhi (10.1016/j.biocel.2018.01.003_bib1240) 2011; 30 Coleman (10.1016/j.biocel.2018.01.003_bib0230) 1998; 77 Pratap (10.1016/j.biocel.2018.01.003_bib0845) 2008; 68 Huang (10.1016/j.biocel.2018.01.003_bib0420) 1994; 94 Jayaraman (10.1016/j.biocel.2018.01.003_bib0450) 2017; 8 Vukmirovic-Popovic (10.1016/j.biocel.2018.01.003_bib1065) 2002; 31 Markowitz (10.1016/j.biocel.2018.01.003_bib0690) 2001; 12 Shi (10.1016/j.biocel.2018.01.003_bib0945) 2004; 343 Pivetta (10.1016/j.biocel.2018.01.003_bib0825) 2011; 13 Trivedi (10.1016/j.biocel.2018.01.003_bib1050) 2017; 8 Walker (10.1016/j.biocel.2018.01.003_bib1075) 2010; 120 Shalhoub (10.1016/j.biocel.2018.01.003_bib0935) 1999; 72 Hortobagyi (10.1016/j.biocel.2018.01.003_bib0415) 1998; 16 Day (10.1016/j.biocel.2018.01.003_bib0265) 2005; 8 Coltrera (10.1016/j.biocel.2018.01.003_bib0250) 1995; 55 Anon (10.1016/j.biocel.2018.01.003_bib0045) 2015 Sutton (10.1016/j.biocel.2018.01.003_bib0990) 2008; 22 Samee (10.1016/j.biocel.2018.01.003_bib0910) 2008; 173 Barasch (10.1016/j.biocel.2018.01.003_bib0100) 2011; 90 Rauch (10.1016/j.biocel.2018.01.003_bib0855) 2010; 11 Lau (10.1016/j.biocel.2018.01.003_bib0565) 2010; 126 Kousteni (10.1016/j.biocel.2018.01.003_bib0545) 2002; 298 Hortobagyi (10.1016/j.biocel.2018.01.003_bib0410) 1996; 335 Lee (10.1016/j.biocel.2018.01.003_bib0580) 2001; 37 Zhang (10.1016/j.biocel.2018.01.003_bib1190) 2004; 24 Li (10.1016/j.biocel.2018.01.003_bib0630) 2015; 17 Zhao (10.1016/j.biocel.2018.01.003_bib1230) 2007; 67 Wilmanski (10.1016/j.biocel.2018.01.003_bib1085) 2016; 68 Hagiwara (10.1016/j.biocel.2018.01.003_bib0380) 2014; 17 Lüftner (10.1016/j.biocel.2018.01.003_bib0560) 2014; 3 Neve (10.1016/j.biocel.2018.01.003_bib0760) 2011; 343 Xu (10.1016/j.biocel.2018.01.003_bib1120) 2013; 1 Negishi-Koga (10.1016/j.biocel.2018.01.003_bib0755) 2011; 17 Crotti (10.1016/j.biocel.2018.01.003_bib0255) 2006; 372 Lehenkari (10.1016/j.biocel.2018.01.003_bib0600) 2002; 61 Nannuru (10.1016/j.biocel.2018.01.003_bib0750) 2010; 70 Xian (10. |
| References_xml | – volume: 286 start-page: 32995 year: 2011 end-page: 33002 ident: bib1025 article-title: Osteoblast-specific transcription factor Osterix (Osx) is an upstream regulator of Satb2 during bone formation publication-title: J. Biol. Chem. contributor: fullname: Tang – volume: 80 start-page: 1572 year: 1997 end-page: 1580 ident: bib0375 article-title: Parathyroid hormone-related protein and bone metastases publication-title: Cancer contributor: fullname: Guise – volume: 31 year: 2013 ident: bib0360 article-title: Denosumab versus placebo as adjuvant treatment for women with early-stage breast cancer at high risk of disease recurrence (D-CARE): an international, placebo-controlled, randomized, double-blind phase III clinical trial publication-title: J. Clin. Oncol. contributor: fullname: Goss – year: 2011 ident: bib0655 article-title: PD01-02: Randomized Phase II Study of Dasatinib Vs Placebo in Addition to Exemestane in Advanced ER/PR-Positive Breast Cancer [BMS CA180-261 Study] contributor: fullname: Llombart – volume: 8 start-page: 6169 year: 2017 ident: bib0450 article-title: Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA publication-title: Oncotarget contributor: fullname: Kominsky – volume: 11 start-page: 1779 year: 2015 ident: bib0980 article-title: Hypercalcemia of malignancy and new treatment options publication-title: Ther. Clin. Risk Manage. contributor: fullname: Glezerman – volume: 4 start-page: 2989 year: 1990 end-page: 3000 ident: bib0955 article-title: Cellular signaling by peptides of the endothelin gene family publication-title: FASEB J. contributor: fullname: Dunn – volume: 63 start-page: 5028 year: 2003 end-page: 5033 ident: bib0735 article-title: C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis publication-title: Cancer Res. contributor: fullname: Myoui – volume: 13 start-page: R105 year: 2011 ident: bib0825 article-title: MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases publication-title: Breast Cancer Res. contributor: fullname: Pivetta – volume: 21 start-page: 456 year: 2006 end-page: 465 ident: bib1220 article-title: Pharmacological sequestration of intracellular cholesterol in late endosomes disrupts ruffled border formation in osteoclasts publication-title: J. Bone Miner. Res. contributor: fullname: Väänänen – volume: 7 start-page: e39871 year: 2012 ident: bib0770 article-title: Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation publication-title: PLoS One contributor: fullname: Nicolaidou – volume: 7 start-page: e29862 year: 2012 ident: bib1030 article-title: An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment publication-title: PLoS One contributor: fullname: Thiolloy – volume: 386 start-page: 433 year: 2015 end-page: 443 ident: bib0345 article-title: Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial publication-title: Lancet contributor: fullname: Gnant – volume: 92 start-page: 1531 year: 2005 end-page: 1537 ident: bib0025 article-title: Vascular endothelial growth factor acts as an osteolytic factor in breast cancer metastases to bone publication-title: Br. J. Cancer contributor: fullname: Aldridge – volume: 70 start-page: 3494 year: 2010 end-page: 3504 ident: bib0750 article-title: Matrix metalloproteinase (MMP)-13 regulates mammary Tumor–induced osteolysis by activating MMP9 and transforming growth factor-β signaling at the tumor-bone interface publication-title: Cancer Res. contributor: fullname: Nannuru – volume: 290 start-page: 6903 year: 2015 end-page: 6912 ident: bib0905 article-title: Wnt/β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cells publication-title: J. Biol. Chem. contributor: fullname: Saidak – volume: 37 start-page: 106 year: 2001 end-page: 113 ident: bib0580 article-title: A matrix metalloproteinase inhibitor: batimastat, retards the development of osteolytic bone metastases by MDA-MB-231 human breast cancer cells in Balb C nu/nu mice publication-title: Eur. J. Cancer contributor: fullname: Lee – volume: 80 start-page: 1588 year: 1997 end-page: 1594 ident: bib0240 article-title: Skeletal complications of malignancy publication-title: Cancer contributor: fullname: Coleman – volume: 49 start-page: 623 year: 2011 end-page: 635 ident: bib0605 article-title: The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking publication-title: Bone contributor: fullname: Leung – volume: 12 start-page: 1164 year: 2001 end-page: 1172 ident: bib0690 article-title: Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate publication-title: J. Am. Soc. Nephrol. contributor: fullname: Markowitz – volume: 21 start-page: 1924 year: 2006 end-page: 1934 ident: bib0425 article-title: Calcitonin deficiency in mice progressively results in high bone turnover publication-title: J. Bone Miner. Res. contributor: fullname: Huebner – volume: 99 start-page: 1901 year: 1984 end-page: 1906 ident: bib0170 article-title: Osteoclast formation from mononuclear phagocytes: role of bone-forming cells publication-title: J. Cell Biol. contributor: fullname: Nijweide – volume: 17 start-page: 1473 year: 2011 end-page: 1480 ident: bib0755 article-title: Suppression of bone formation by osteoclastic expression of semaphorin 4D publication-title: Nat. Med. contributor: fullname: Negishi-Koga – volume: 23 start-page: 2025 year: 2008 end-page: 2032 ident: bib1070 article-title: Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling publication-title: J. Bone Miner. Res. contributor: fullname: Walker – volume: 116 start-page: 1195 year: 2006 ident: bib1165 article-title: The stem cell niches in bone publication-title: J. Clin. Invest. contributor: fullname: Li – volume: 102 start-page: 881 year: 1998 ident: bib0305 article-title: PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha (v) beta3 integrin, and phosphorylated by src kinase publication-title: J. Clin. Invest. contributor: fullname: Duong – volume: 123 start-page: 1034 year: 2008 end-page: 1042 ident: bib0150 article-title: Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases publication-title: Int. J. Cancer contributor: fullname: Bu – volume: 6 start-page: 32804 year: 2016 ident: bib1115 article-title: CD147/EMMPRIN overexpression and prognosis in cancer: a systematic review and meta-analysis publication-title: Sci. Rep. contributor: fullname: Xin – volume: 100 start-page: 10954 year: 2003 end-page: 10959 ident: bib1175 article-title: A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases publication-title: Proc. Natl. Acad. Sci. contributor: fullname: Yin – volume: 443 start-page: 694 year: 2014 end-page: 699 ident: bib0470 article-title: A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Jensen – start-page: djs485 year: 2012 ident: bib0325 article-title: Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1 publication-title: J. Natl. Cancer Inst. contributor: fullname: Fang – volume: 28 start-page: 912 year: 2013 end-page: 925 ident: bib1005 article-title: EphrinB2/EphB4 inhibition in the osteoblast lineage modifies the anabolic response to parathyroid hormone publication-title: J. Bone Miner. Res. contributor: fullname: Takyar – volume: 343 start-page: 117 year: 2004 end-page: 126 ident: bib0945 article-title: YY1 is involved in RANKL-induced transcription of the tartrate-resistant acid phosphatase gene in osteoclast differentiation publication-title: Gene contributor: fullname: Shi – volume: 253 start-page: 395 year: 1998 end-page: 400 ident: bib0740 article-title: RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Nakagawa – volume: 105 start-page: 18 year: 2014 end-page: 25 ident: bib0765 article-title: Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2 publication-title: Cancer Sci. contributor: fullname: Ni – volume: 335 start-page: 1785 year: 1996 end-page: 1792 ident: bib0410 article-title: Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases publication-title: New Engl. J. Med. contributor: fullname: Hortobagyi – volume: 27 start-page: 1564 year: 2009 end-page: 1571 ident: bib0335 article-title: Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer: breast cancer, or other neoplasms after intravenous bisphosphonates publication-title: J. Clin. Oncol. contributor: fullname: Fizazi – volume: 345 start-page: 442 year: 1990 ident: bib1185 article-title: The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene publication-title: Nature contributor: fullname: Yoshida – volume: 67 start-page: 1513 year: 1970 end-page: 1520 ident: bib0030 article-title: Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage publication-title: Proc. Natl. Acad. Sci. contributor: fullname: Anderson – volume: 41 start-page: 59 year: 1969 end-page: 72 ident: bib0040 article-title: Vesicles associated with calcification in the matrix of epiphyseal cartilage publication-title: J. Cell Biol. contributor: fullname: Anderson – volume: 105 start-page: 20764 year: 2008 end-page: 20769 ident: bib0815 article-title: Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate publication-title: Proc. Natl. Acad. Sci. contributor: fullname: Pederson – volume: 14 start-page: 1099 year: 2016 end-page: 1106 ident: bib0650 article-title: Immunolocalization of MMP9 and MMP2 in osteolytic metastasis originating from MDA-MB-231 human breast cancer cells publication-title: Mol. Med. Rep. contributor: fullname: Liu – volume: 66 start-page: 6714 year: 2006 end-page: 6721 ident: bib0095 article-title: Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-β type I receptor kinase inhibitor publication-title: Cancer Res. contributor: fullname: Bandyopadhyay – volume: 103 start-page: 197 year: 1999 end-page: 206 ident: bib1170 article-title: TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development publication-title: J. Clin. Invest. contributor: fullname: Yin – volume: 157 start-page: 528 year: 1993 end-page: 534 ident: bib1155 article-title: Plasminogen-dependent activation of latent transforming growth factor beta (TGFβ) by growing cultures of osteoblast-like cells publication-title: J. Cell. Physiol. contributor: fullname: Yee – volume: 322 start-page: 1106 year: 1990 end-page: 1112 ident: bib0175 article-title: Immunochemical characterization of circulating parathyroid hormone–related protein in patients with humoral hypercalcemia of cancer publication-title: New Engl. J. Med. contributor: fullname: Burtis – volume: 107 start-page: 1118 year: 2009 end-page: 1128 ident: bib0355 article-title: Bone sialoprotein stimulates focal adhesion-related signaling pathways: role in migration and survival of breast and prostate cancer cells publication-title: J. Cell. Biochem. contributor: fullname: Gordon – volume: 67 start-page: 8742 year: 2007 end-page: 8751 ident: bib0155 article-title: Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer publication-title: Cancer Res. contributor: fullname: Buijs – volume: 190 start-page: 1741 year: 1999 end-page: 1754 ident: bib0070 article-title: Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor κB (RANK) receptors publication-title: J. Exp. Med. contributor: fullname: Arai – volume: 21 start-page: 761 year: 2009 ident: bib0860 article-title: Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone publication-title: Oncol. Rep. contributor: fullname: Richert – volume: 21 start-page: 1618 year: 2006 end-page: 1626 ident: bib0090 article-title: Vitamin D action and regulation of bone remodeling: suppression of osteoclastogenesis by the mature osteoblast publication-title: J. Bone Miner. Res. contributor: fullname: Baldock – volume: 265 start-page: 1573 year: 1994 end-page: 1578 ident: bib0930 article-title: Requirement of transcription factor PU: 1 in the development of multiple hematopoietic lineages publication-title: Science contributor: fullname: Scott – volume: 78 start-page: 205 year: 2003 end-page: 216 ident: bib1090 article-title: Estradiol enhances osteolytic lesions in mice inoculated with human estrogen receptor-negative MDA-231 breast cancer cells in vivo publication-title: Breast Cancer Res. Treat. contributor: fullname: Winding – volume: 21 start-page: 486 year: 2007 end-page: 498 ident: bib0220 article-title: Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation publication-title: Mol. Endocrinol. contributor: fullname: Clines – volume: 68 start-page: 7795 year: 2008 end-page: 7802 ident: bib0845 article-title: Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells publication-title: Cancer Res. contributor: fullname: Pratap – volume: 97 start-page: 7829 year: 2000 end-page: 7834 ident: bib0940 article-title: Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression publication-title: Proc. Natl. Acad. Sci. contributor: fullname: Shevde – volume: 68 start-page: 1202 year: 2016 end-page: 1209 ident: bib1085 article-title: 1α: 25-Dihydroxyvitamin D inhibits the metastatic capability of MCF10CA1a and MDA-MB-231cells in an in vitro model of breast to bone metastasis publication-title: Nutr. Cancer contributor: fullname: Wilmanski – volume: 70 start-page: 6150 year: 2010 end-page: 6160 ident: bib0890 article-title: Receptor activator of NF-κB ligand enhances breast cancer–induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147 publication-title: Cancer Res. contributor: fullname: Rucci – volume: 17 start-page: 4456 year: 1998 end-page: 4468 ident: bib0275 article-title: PU. 1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors publication-title: EMBO J. contributor: fullname: Singh – volume: 140 start-page: 4451 year: 1999 end-page: 4458 ident: bib1035 article-title: Breast cancer cells interact with osteoblasts to support osteoclast formation 1 publication-title: Endocrinology contributor: fullname: Thomas – volume: 95 start-page: 3597 year: 1998 end-page: 3602 ident: bib1150 article-title: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL publication-title: Proc. Natl. Acad. Sci. contributor: fullname: Yasuda – volume: 3 start-page: 537 year: 2003 end-page: 549 ident: bib0485 article-title: A multigenic program mediating breast cancer metastasis to bone publication-title: Cancer Cell contributor: fullname: Kang – volume: 123 start-page: 666 year: 2013 end-page: 681 ident: bib0660 article-title: Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation publication-title: J. Clin. Invest. contributor: fullname: Lotinun – volume: 277 start-page: 24571 year: 2002 end-page: 24578 ident: bib0480 article-title: Transforming growth factor-β stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways publication-title: J. Biol. Chem. contributor: fullname: Käkönen – volume: 67 start-page: 9894 year: 2007 end-page: 9902 ident: bib0575 article-title: A Cathepsin K inhibitor reduces breast cancer–induced osteolysis and skeletal tumor burden publication-title: Cancer Res. contributor: fullname: Le Gall – volume: 314 start-page: 2334 year: 2008 end-page: 2351 ident: bib0005 article-title: Osteoactivin: an anabolic factor that regulates osteoblast differentiation and function publication-title: Exp. Cell Res. contributor: fullname: Abdelmagid – volume: 16 start-page: 458 year: 2014 ident: bib0950 article-title: Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis publication-title: Breast Cancer Res.: BCR contributor: fullname: Siclari – volume: 108 start-page: 17 year: 2002 end-page: 29 ident: bib0745 article-title: The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation publication-title: Cell contributor: fullname: Nakashima – volume: 410 start-page: 50 year: 2001 end-page: 56 ident: bib0680 article-title: Involvement of chemokine receptors in breast cancer metastasis publication-title: Nature contributor: fullname: Müller – volume: 11 start-page: 306 year: 2005 end-page: 314 ident: bib0610 article-title: Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice publication-title: Clin. Cancer Res. contributor: fullname: Lev – volume: 8 start-page: 26687 year: 2017 ident: bib1050 article-title: The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm publication-title: Oncotarget contributor: fullname: Trivedi – volume: 118 start-page: 5479 year: 2005 end-page: 5487 ident: bib1145 article-title: NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP publication-title: J. Cell Sci. contributor: fullname: Yaroslavskiy – volume: 48 start-page: S17 year: 2011 ident: bib0015 article-title: A phase II, randomized, open-label, pilot study to evaluate the safety and the effects on bone resorption of saracatinib (AZD0530) in patients with prostate cancer or breast cancer with metastatic bone disease publication-title: Bone contributor: fullname: Aklilu – volume: 17 start-page: 173 year: 2015 end-page: 179 ident: bib0320 article-title: Differences of osteoblastic bone metastases and osteolytic bone metastases in clinical features and molecular characteristics publication-title: Clin. Trans. Oncol. contributor: fullname: Xu – volume: 28 start-page: 5132 year: 2010 end-page: 5139 ident: bib0985 article-title: Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study publication-title: J. Clin. Oncol. contributor: fullname: Stopeck – volume: 191 start-page: 39 year: 1997 end-page: 48 ident: bib0085 article-title: Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone publication-title: J. Anat. contributor: fullname: BORD – volume: 282 start-page: 33098 year: 2007 end-page: 33106 ident: bib0620 article-title: Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts publication-title: J. Biol. Chem. contributor: fullname: Li – year: 2017 ident: bib0065 article-title: Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast Cancer contributor: fullname: Anon – volume: 2 start-page: 137 year: 2013 end-page: 144 ident: bib0550 article-title: Incidence: consequences and treatment of bone metastases in breast cancer patients–experience from a single cancer centre publication-title: Journal of Bone Oncology contributor: fullname: Kuchuk – volume: 17 start-page: 223 year: 2014 end-page: 230 ident: bib0380 article-title: Healthcare costs associated with skeletal-related events in breast cancer patients with bone metastases publication-title: J. Med. Econ. contributor: fullname: Chung – volume: 25 start-page: 8581 year: 2005 end-page: 8591 ident: bib0840 article-title: The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion publication-title: Mol. Cell. Biol. contributor: fullname: Pratap – volume: 38 start-page: 427 year: 2014 end-page: 434 ident: bib0385 article-title: Incidence of bone metastases and survival after a diagnosis of bone metastases in breast cancer patients publication-title: Cancer Epidemiol. contributor: fullname: Harries – volume: 63 start-page: 1567 year: 2005 end-page: 1575 ident: bib0705 article-title: Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment publication-title: J. Oral Maxillofac. Surg. contributor: fullname: Marx – volume: 7 start-page: 280 year: 2016 ident: bib0700 article-title: Prevention of bone loss in a model of postmenopausal osteoporosis through adrenomedullin inhibition publication-title: Front. Physiol. contributor: fullname: Martínez-Herrero – volume: 12 start-page: 215 year: 2010 ident: bib0195 article-title: Breast cancer metastasis to the bone: mechanisms of bone loss publication-title: Breast Cancer Res. contributor: fullname: Mastro – volume: 386 start-page: 81 year: 1997 ident: bib1040 article-title: Osteopetrosis in mice lacking haematopoietic transcription factor PU . 1 publication-title: Nature contributor: fullname: Tondravi – volume: 67 start-page: 9542 year: 2007 end-page: 9548 ident: bib1235 article-title: Accelerated bone resorption: due to dietary calcium deficiency, promotes breast cancer tumor growth in bone publication-title: Cancer Res. contributor: fullname: Zheng – volume: 64 start-page: 281 year: 2003 end-page: 289 ident: bib0695 article-title: Toxic acute tubular necrosis following treatment with zoledronate (Zometa) publication-title: Kidney Int. contributor: fullname: Markowitz – volume: 125 start-page: 971 year: 2006 end-page: 986 ident: bib0280 article-title: SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation publication-title: Cell contributor: fullname: Dobreva – volume: 72 start-page: 251 year: 1999 end-page: 261 ident: bib0935 article-title: Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors publication-title: J. Cell. Biochem. contributor: fullname: Shalhoub – volume: 104 start-page: 205 year: 2001 end-page: 215 ident: bib0530 article-title: Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man publication-title: Cell contributor: fullname: Kornak – volume: 38 start-page: 497 year: 2006 end-page: 508 ident: bib0475 article-title: Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing publication-title: Bone contributor: fullname: Jung – volume: 89 start-page: 1927 year: 2003 end-page: 1933 ident: bib0790 article-title: Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer publication-title: Br. J. Cancer contributor: fullname: Oehler – volume: 107 start-page: 1898 year: 2016 end-page: 1908 ident: bib0710 article-title: CITED2 in breast carcinoma as a potent prognostic predictor associated with proliferation: migration and chemoresistance publication-title: Cancer Sci. contributor: fullname: Minemura – volume: 10 start-page: 625 year: 1995 end-page: 631 ident: bib0725 article-title: Expression and regulation of Na-Dependent pi transport in matrix vesicles produced by osteoblast-like cells publication-title: J. Bone Miner. Res. contributor: fullname: Caverzasio – volume: 26 start-page: 3789 year: 2007 ident: bib0965 article-title: COX-2 involvement in breast cancer metastasis to bone publication-title: Oncogene contributor: fullname: Singh – volume: 335 start-page: 1016 year: 1996 end-page: 1021 ident: bib0270 article-title: Esophagitis associated with the use of alendronate publication-title: New Engl. J. Med. contributor: fullname: De Groen – volume: 27 start-page: 3757 year: 2009 end-page: 3763 ident: bib0350 article-title: Prognostic effects of 25-hydroxyvitamin D levels in early breast cancer publication-title: J. Clin. Oncol. contributor: fullname: Goodwin – volume: 23 start-page: 1157 year: 2015 end-page: 1168 ident: bib0810 article-title: Pain outcomes in patients with bone metastases from advanced cancer: assessment and management with bone-targeting agents publication-title: Support. Care Cancer contributor: fullname: Patrick – volume: 120 start-page: 582 year: 2010 end-page: 592 ident: bib1075 article-title: Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice publication-title: J. Clin. Invest. contributor: fullname: Walker – year: 2012 ident: bib1100 article-title: Bisphosphonates and Other Bone Agents for Breast Cancer contributor: fullname: Pavlakis – volume: 23 start-page: 3314 year: 2005 end-page: 3321 ident: bib0520 article-title: Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: a randomized, placebo-controlled trial publication-title: J. Clin. Oncol. contributor: fullname: Kohno – volume: 116 start-page: 1230 year: 2006 end-page: 1242 ident: bib0685 article-title: Placental growth factor mediates mesenchymal cell development: cartilage turnover, and bone remodeling during fracture repair publication-title: J. Clin. Invest. contributor: fullname: Maes – volume: 372 start-page: 92 year: 2006 end-page: 102 ident: bib0255 article-title: NFATc1 regulation of the human β3 integrin promoter in osteoclast differentiation publication-title: Gene contributor: fullname: Crotti – volume: 10 start-page: 452 year: 2010 end-page: 458 ident: bib0460 article-title: The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial publication-title: Clin. Breast Cancer contributor: fullname: Jensen – volume: 287 start-page: 7169 year: 2012 end-page: 7181 ident: bib0190 article-title: Membrane estrogen signaling enhances tumorigenesis and metastatic potential of breast cancer cells via estrogen receptor-α36 αER(36) publication-title: J. Biol. Chem. contributor: fullname: Chaudhri – volume: 89 start-page: 771 year: 2003 end-page: 777 ident: bib0505 article-title: Vitamin D3 supports osteoclastogenesis via functional vitamin D response element of human RANKL gene promoter publication-title: J. Cell. Biochem. contributor: fullname: Kitazawa – volume: 16 start-page: 1486 year: 2001 end-page: 1495 ident: bib1180 article-title: A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro publication-title: J. Bone Miner. Res. contributor: fullname: Yoneda – volume: 98 start-page: 1544 year: 1996 ident: bib0365 article-title: Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis publication-title: J. Clin. Invest. contributor: fullname: Guise – volume: 175 start-page: 1255 year: 2009 end-page: 1269 ident: bib0830 article-title: Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis publication-title: Am. J. Pathol. contributor: fullname: Podgorski – volume: 15 start-page: 757 year: 2009 end-page: 765 ident: bib1020 article-title: TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation publication-title: Nat. Med. contributor: fullname: Tang – volume: 296 start-page: 235 year: 2001 end-page: 242 ident: bib0295 article-title: Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates publication-title: J. Pharmacol. Exp. Ther. contributor: fullname: Dunford – volume: 121 start-page: 277 year: 2010 end-page: 280 ident: bib0515 article-title: The metabolism of 25-(OH) vitamin D 3 by osteoclasts and their precursors regulates the differentiation of osteoclasts publication-title: J. Steroid Biochem. Mol. Biol. contributor: fullname: Kogawa – volume: 583 start-page: 2435 year: 2009 end-page: 2440 ident: bib0970 article-title: Regulatory mechanism of NFATc1 in RANKL‐induced osteoclast activation publication-title: FEBS Lett. contributor: fullname: Song – volume: 101 start-page: 6158 year: 2004 end-page: 6163 ident: bib0675 article-title: The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase publication-title: Proc. Natl. Acad. Sci. U. S. A. contributor: fullname: Mócsai – volume: 6 start-page: e27090 year: 2011 ident: bib0125 article-title: Anti-transforming growth factor ss antibody treatment rescues bone loss and prevents breast cancer metastasis to bone publication-title: PLoS One contributor: fullname: Biswas – volume: 216 start-page: 35 year: 1995 end-page: 45 ident: bib0670 article-title: The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization publication-title: Exp. Cell Res. contributor: fullname: Lynch – volume: 23 start-page: 499 year: 1998 end-page: 509 ident: bib1135 article-title: Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur publication-title: Bone contributor: fullname: Yamaza – volume: 104 start-page: 719 year: 2001 end-page: 730 ident: bib0540 article-title: Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity publication-title: Cell contributor: fullname: Kousteni – volume: 89 start-page: 755 year: 1997 end-page: 764 ident: bib0525 article-title: Targeted disruption of Cbfa1results in a complete lack of bone formation owing to maturational arrest of osteoblasts publication-title: Cell contributor: fullname: Komori – volume: 190 start-page: 293 year: 1999 end-page: 298 ident: bib0775 article-title: Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption publication-title: J. Exp. Med. contributor: fullname: Niida – volume: 14 start-page: 730 year: 2016 end-page: 739 ident: bib0445 article-title: CITED2 modulates breast cancer metastatic ability through effects on IKKα publication-title: Mol. Cancer Res. contributor: fullname: Jayaraman – volume: 8 start-page: 739 year: 2005 end-page: 750 ident: bib0265 article-title: Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis publication-title: Dev. Cell contributor: fullname: Day – volume: 30 start-page: 1138 year: 2015 end-page: 1149 ident: bib1055 article-title: The effects of androgens on murine cortical bone do not require AR or ERα signaling in osteoblasts and osteoclasts publication-title: J. Bone Miner. Res. contributor: fullname: Ucer – volume: 286 start-page: 42575 year: 2011 end-page: 42584 ident: bib0200 article-title: Regulation of breast cancer-induced bone lesions by β-catenin protein signaling publication-title: J. Biol. Chem. contributor: fullname: Chen – volume: 22 start-page: 1370 year: 2008 end-page: 1381 ident: bib0990 article-title: Semaphorin 3B is a 1: 25-Dihydroxyvitamin D3-induced gene in osteoblasts that promotes osteoclastogenesis and induces osteopenia in mice publication-title: Mol. Endocrinol. contributor: fullname: Sutton – volume: 125 start-page: 2028S year: 1995 ident: bib0975 article-title: Endothelin receptors, second messengers, and actions in bone publication-title: J. Nutr. contributor: fullname: Stern – volume: 120 start-page: 549 year: 2012 end-page: 557 ident: bib1210 article-title: c-Src expression is predictive of poor prognosis in breast cancer patients with bone metastasis: but not in patients with visceral metastasis publication-title: APMIS contributor: fullname: Zhang – volume: 119 start-page: 1776 year: 1986 end-page: 1785 ident: bib0120 article-title: 1, 25-Dihydroxyvitamin D3 and human bone-derived cells in vitro: effects on alkaline phosphatase, type I collagen and proliferation publication-title: Endocrinology contributor: fullname: Russell – volume: 72 start-page: 4238 year: 2012 end-page: 4249 ident: bib0395 article-title: Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases publication-title: Cancer Res. contributor: fullname: Hiraga – volume: 19 start-page: 1059 year: 2004 end-page: 1066 ident: bib0110 article-title: A single-dose placebo-controlled study of AMG 162: a fully human monoclonal antibody to RANKL, in postmenopausal women publication-title: J. Bone Miner. Res. contributor: fullname: Bekker – volume: 140 start-page: 4382 year: 1999 end-page: 4389 ident: bib0400 article-title: Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis 1 publication-title: Endocrinology contributor: fullname: Hofbauer – volume: 100 start-page: 2613 year: 2004 end-page: 2621 ident: bib0880 article-title: Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors publication-title: Cancer contributor: fullname: Rosen – volume: 66 start-page: 4117 year: 2006 end-page: 4124 ident: bib0405 article-title: Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells publication-title: Cancer Res. contributor: fullname: Holland – volume: 27 start-page: 165 year: 2001 end-page: 176 ident: bib0245 article-title: Metastatic bone disease: clinical features, pathophysiology and treatment strategies publication-title: Cancer Treatment Rev. contributor: fullname: Coleman – volume: 94 start-page: 560 year: 1994 ident: bib0420 article-title: Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta publication-title: J. Clin. Invest. contributor: fullname: Huang – volume: 88 start-page: 1082 year: 2000 end-page: 1090 ident: bib0635 article-title: Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases publication-title: Cancer contributor: fullname: Lipton – volume: 7 start-page: 79688 year: 2016 ident: bib1015 article-title: Breast cancer cells obtain an osteomimetic feature via epithelial-mesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction publication-title: Oncotarget contributor: fullname: Tan – volume: 23 start-page: 279 year: 2002 end-page: 302 ident: bib0865 article-title: Sex steroids and the construction and conservation of the adult skeleton publication-title: Endocr. Rev. contributor: fullname: Melton – volume: 110 start-page: 1767 year: 1997 end-page: 1780 ident: bib0805 article-title: Endocytic pathway from the basal plasma membrane to the ruffled border membrane in bone-resorbing osteoclasts publication-title: J. Cell Sci. contributor: fullname: Vaananen – volume: 40 start-page: 1517 year: 2007 end-page: 1528 ident: bib0080 article-title: Metabolism of vitamin D 3 in human osteoblasts: evidence for autocrine and paracrine activities of 1α, 25-dihydroxyvitamin D 3 publication-title: Bone contributor: fullname: Atkins – year: 2008 ident: bib1010 article-title: Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone publication-title: Int. J. Oncol. contributor: fullname: Tamura – volume: 78 start-page: 354 year: 1996 ident: bib0160 article-title: Parathyroid hormone-related protein, bone metastases and hypercalcaemia of malignancy publication-title: Ann. R. Coll. Surg. Engl. contributor: fullname: Ratcliffe – volume: 22 start-page: 992 year: 2007 end-page: 1001 ident: bib1130 article-title: Induction of DC‐STAMP by alternative activation and downstream signaling mechanisms publication-title: J. Bone Miner. Res. contributor: fullname: Yagi – volume: 67 start-page: 5821 year: 2007 end-page: 5830 ident: bib1230 article-title: Tumor αvβ3 integrin is a therapeutic target for breast cancer bone metastases publication-title: Cancer Res. contributor: fullname: Zhao – volume: 15 start-page: 997 year: 2014 end-page: 1006 ident: bib0235 article-title: Adjuvant zoledronic acid in patients with early breast cancer: final efficacy analysis of the AZURE (BIG 01/04) randomised open-label phase 3 trial publication-title: Lancet Oncol. contributor: fullname: Coleman – volume: 207 start-page: 2793 year: 2010 end-page: 2798 ident: bib0440 article-title: Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo publication-title: J. Exp. Med. contributor: fullname: Ishii – volume: 70 start-page: 1835 year: 2010 end-page: 1844 ident: bib0800 article-title: Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis publication-title: Cancer Res. contributor: fullname: Ooi – volume: 318 start-page: 161 year: 2006 end-page: 172 ident: bib0885 article-title: Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy publication-title: J. Pharmacol. Exp. Ther. contributor: fullname: Rucci – volume: 11 start-page: 517 year: 2010 end-page: 531 ident: bib0855 article-title: Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor publication-title: Cell Metab. contributor: fullname: Rauch – volume: 13 start-page: 2898 year: 2014 end-page: 2909 ident: bib0310 article-title: Efficacy of a cathepsin K inhibitor in a preclinical model for prevention and treatment of breast cancer bone metastasis publication-title: Mol. Cancer Ther. contributor: fullname: Duong – volume: 62 start-page: 917 year: 2002 end-page: 923 ident: bib1160 article-title: Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer publication-title: Cancer Res. contributor: fullname: Yi – volume: 12 start-page: 4393 year: 2016 end-page: 4398 ident: bib0835 article-title: Cadherin-11 expression is upregulated in invasive human breast cancer publication-title: Oncol. Lett. contributor: fullname: Pohlodek – volume: 63 start-page: 2631 year: 2003 end-page: 2637 ident: bib0105 article-title: Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells publication-title: Cancer Res. contributor: fullname: Barnes – volume: 128 start-page: 1253 year: 2001 end-page: 1264 ident: bib0145 article-title: Inactivation of the (β)-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development publication-title: Development contributor: fullname: Brault – volume: 126 start-page: 876 year: 2010 end-page: 884 ident: bib0565 article-title: Identification of prospective factors promoting osteotropism in breast cancer: a potential role for CITED2 publication-title: Int. J. Cancer contributor: fullname: Lau – volume: 15 start-page: 97 year: 2017 ident: bib0205 article-title: Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers publication-title: J. Transl. Med. contributor: fullname: Chiu – volume: 4 start-page: e6896 year: 2009 ident: bib0300 article-title: Hypoxia and TGF-β drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment publication-title: PLoS One contributor: fullname: Dunn – volume: 156 start-page: 1604 year: 1982 end-page: 1614 ident: bib0165 article-title: In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes publication-title: J. Exp. Med. contributor: fullname: Burger – year: 2016 ident: bib0050 article-title: Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis contributor: fullname: Anon – volume: 390 start-page: 175 year: 1997 end-page: 179 ident: bib0035 article-title: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function publication-title: Nature contributor: fullname: Anderson – volume: 22 start-page: 176 year: 2008 end-page: 185 ident: bib0495 article-title: NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP) publication-title: Mol. Endocrinol. contributor: fullname: Kim – volume: 5 start-page: 587 year: 1998 end-page: 592 ident: bib0390 article-title: Clinical and autopsy findings in spinal cord compression due to metastatic disease publication-title: Eur. J. Neurol. contributor: fullname: Laursen – volume: 130 start-page: 1401 year: 1992 end-page: 1412 ident: bib0185 article-title: Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex publication-title: Endocrinology contributor: fullname: Campbell – volume: 303 start-page: 303 year: 1994 end-page: 311 ident: bib0870 article-title: Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum publication-title: Biochem. J contributor: fullname: Rogers – volume: 22 start-page: 5706 year: 2016 end-page: 5712 ident: bib0715 article-title: TBCRC-010: phase I/II study of dasatinib in combination with zoledronic acid for the treatment of Breast cancer bone metastasis publication-title: Clin. Cancer Res. contributor: fullname: Mitri – volume: 208 start-page: 123 year: 1999 end-page: 133 ident: bib0720 article-title: A BMP-inducible gene: dlx5, regulates osteoblast differentiation and mesoderm induction publication-title: Dev. Biol. contributor: fullname: Miyama – volume: 343 start-page: 289 year: 2011 end-page: 302 ident: bib0760 article-title: Osteoblast physiology in normal and pathological conditions publication-title: Cell Tissue Res. contributor: fullname: Cantatore – volume: 18 start-page: 1095 year: 2012 end-page: 1101 ident: bib1110 article-title: Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells publication-title: Nat. Med. contributor: fullname: Xian – volume: 136 year: 2015 ident: bib0330 article-title: Cancer incidence and mortality worldwide: sources methods and major patterns in GLOBOCAN 2012 publication-title: Int. J. Cancer contributor: fullname: Ferlay – volume: 43 start-page: 89 year: 2011 end-page: 95 ident: bib0595 article-title: Implications of bone-only metastases in breast cancer: favorable preference with excellent outcomes of hormone receptor positive breast cancer publication-title: Cancer Research and Treatment contributor: fullname: Lee – volume: 57 start-page: 5386 year: 1997 end-page: 5390 ident: bib0645 article-title: The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma publication-title: Cancer Res. contributor: fullname: Littlewood-Evans – year: 2017 ident: bib0055 article-title: S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer contributor: fullname: Anon – volume: 187 start-page: 218 year: 2001 end-page: 225 ident: bib0510 article-title: Endothelin-1 expression in long-term cultures of fetal rat calvarial osteoblasts: regulation by BMP-7 publication-title: Journal of Cellular Physiology contributor: fullname: Andrews – volume: 269 start-page: 25742 year: 1994 end-page: 25746 ident: bib0340 article-title: Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures publication-title: J. Biol. Chem. contributor: fullname: Fowlkes – volume: 15 start-page: 1370 year: 2001 end-page: 1380 ident: bib0455 article-title: Inhibitory effects of 1α: 25-dihydroxyvitamin D3 on the G1–S phase-controlling machinery publication-title: Mol. Endocrinol. contributor: fullname: Jensen – volume: 31 start-page: 529 year: 2002 end-page: 535 ident: bib1065 article-title: Morphological: histomorphometric, and microstructural alterations in human bone metastasis from breast carcinoma publication-title: Bone contributor: fullname: Vukmirovic-Popovic – volume: 77 start-page: 336 year: 1998 ident: bib0230 article-title: Clinical course and prognostic factors following bone recurrence from breast cancer publication-title: Br. J. Cancer contributor: fullname: Rubens – volume: 5 start-page: 1001 year: 2007 end-page: 1014 ident: bib0875 article-title: Osteoactivin promotes breast cancer metastasis to bone publication-title: Mol. Cancer Res. contributor: fullname: Rose – volume: 202 start-page: 31 year: 2000 end-page: 37 ident: bib0920 article-title: Expression of major bone extracellular matrix proteins during embryonic osteogenesis in rat mandibles publication-title: Anat. Embryol. (Berl.) contributor: fullname: Sasano – volume: 25 start-page: 5840 year: 2006 end-page: 5851 ident: bib0895 article-title: Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast–osteoblast coupling publication-title: EMBO J. contributor: fullname: Ryu – volume: 300 start-page: 957 year: 2003 end-page: 964 ident: bib0795 article-title: Role of prostaglandin E produced by osteoblasts in osteolysis due to bone metastasis publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Ito – volume: 8 start-page: e66752 year: 2013 ident: bib0570 article-title: Enpp1: a potential facilitator of breast cancer bone metastasis publication-title: PLoS One contributor: fullname: Lau – volume: 26 start-page: 1594 year: 2012 end-page: 1601 ident: bib1095 article-title: Hematopoietic stem cell mobilizing agents G-CSF: cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation publication-title: Leukemia contributor: fullname: Winkler – volume: 4 start-page: 111 year: 2006 end-page: 121 ident: bib1225 article-title: Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis publication-title: Cell Metab. contributor: fullname: Zhao – volume: 3 start-page: 328 year: 2014 ident: bib0560 article-title: Health resource utilization associated with skeletal-related events in patients with advanced breast cancer: results from a prospective, multinational observational study publication-title: SpringerPlus contributor: fullname: Lüftner – volume: 386 start-page: 1353 year: 2015 end-page: 1361 ident: bib0315 article-title: Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials publication-title: Lancet contributor: fullname: E.B.C.T.C. Group – volume: 16 start-page: 2038 year: 1998 end-page: 2044 ident: bib0415 article-title: Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate: publication-title: J. Clin. Oncol. contributor: fullname: Hortobagyi – volume: 333 start-page: 356 year: 1995 end-page: 363 ident: bib0615 article-title: Endothelins publication-title: New Engl. J. Med. contributor: fullname: Levin – volume: 298 start-page: 843 year: 2002 end-page: 846 ident: bib0545 article-title: Reversal of bone loss in mice by nongenotropic signaling of sex steroids publication-title: Science contributor: fullname: Kousteni – volume: 25 start-page: 4431 year: 2007 end-page: 4437 ident: bib0640 article-title: Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases publication-title: J. Clin. Oncol. contributor: fullname: Lipton – volume: 1843 start-page: 815 year: 2014 end-page: 826 ident: bib0115 article-title: Microenvironmental stimuli affect Endothelin-1 signaling responsible for invasiveness and osteomimicry of bone metastasis from breast cancer publication-title: Biochim. et Biophys. Acta (BBA)-Mol. Cell Res. contributor: fullname: Bendinelli – volume: 1 start-page: 11 year: 2013 ident: bib1120 article-title: Osteoclasts: new insights publication-title: Bone. Res. contributor: fullname: Teitelbaum – volume: 278 start-page: 22023 year: 2003 end-page: 22030 ident: bib1045 article-title: From lysosomes to the plasma membrane localization of vacuolar type H+−ATPase with the a3 isoform during osteoclast differentiation publication-title: J. Biol. Chem. contributor: fullname: Toyomura – volume: 3 start-page: 395 year: 2012 end-page: 400 ident: bib1205 article-title: C-Src-mediated RANKL-induced breast cancer cell migration by activation of the ERK and Akt pathway publication-title: Oncology Letters contributor: fullname: Zhang – volume: 7 start-page: e37624 year: 2012 ident: bib1125 article-title: Expression of dickkopf-1 and beta-catenin related to the prognosis of breast cancer patients with triple negative phenotype publication-title: PLoS One contributor: fullname: Xu – volume: 29 start-page: 1221 year: 2011 end-page: 1227 ident: bib1060 article-title: American Society of Clinical Oncology executive summary of the clinical practice guideline update on the role of bone-modifying agents in metastatic breast cancer publication-title: J. Clin. Oncol. contributor: fullname: Van Poznak – volume: 458 start-page: 524 year: 2009 end-page: 528 ident: bib0435 article-title: Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis publication-title: Nature contributor: fullname: Ishii – volume: 21 start-page: 327 year: 2014 end-page: 341 ident: bib0780 article-title: Different molecular profiles are associated with breast cancer cell homing compared with colonisation of bone: evidence using a novel bone-seeking cell line publication-title: Endocr. Relat. Cancer contributor: fullname: Nutter – volume: 3 start-page: e3537 year: 2008 ident: bib0915 article-title: Osteoclasts control osteoblast chemotaxis via PDGF-BB/PDGF receptor beta signaling publication-title: PLoS One contributor: fullname: Sanchez-Fernandez – volume: 48 start-page: S17 year: 2011 ident: bib0020 article-title: A phase II, randomized, open-label, pilot study to evaluate the safety and the effects on bone resorption of saracatinib (AZD0530) in patients with prostate cancer or breast cancer with metastatic bone disease publication-title: Bone contributor: fullname: Aklilu – volume: 70 start-page: 6537 year: 2010 end-page: 6547 ident: bib0225 article-title: Anti–placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation publication-title: Cancer Res. contributor: fullname: Coenegrachts – volume: 17 start-page: 33 year: 1999 end-page: 42 ident: bib0290 article-title: Transforming growth factor β1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells publication-title: Clin. Exp. Metastasis contributor: fullname: Singh – volume: 3 start-page: 889 year: 2002 end-page: 901 ident: bib1000 article-title: Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts publication-title: Dev. Cell contributor: fullname: Takayanagi – volume: 24 start-page: 3557 year: 2016 end-page: 3565 ident: bib0215 article-title: Burden of symptoms associated with development of metastatic bone disease in patients with breast cancer publication-title: Support. Care Cancer contributor: fullname: Cleeland – volume: 119 start-page: 1519 year: 2006 end-page: 1529 ident: bib1105 article-title: The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma publication-title: Int. J. Cancer contributor: fullname: Wu – volume: 335 start-page: 437 year: 2005 end-page: 446 ident: bib0555 article-title: The hematopoietic transcription factor PU: 1 regulates RANK gene expression in myeloid progenitors publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Kwon – volume: 24 start-page: 1361 year: 2004 ident: bib1190 article-title: Bone sialoprotein promotes bone metastasis of a non-bone-seeking clone of human breast cancer cells publication-title: Anticancer Res. contributor: fullname: Zhang – volume: 2 start-page: 1132 year: 1996 end-page: 1136 ident: bib0430 article-title: Estrogen promotes apoptosis of murine osteoclasts mediated by TGF–β publication-title: Nat. Med. contributor: fullname: Hughes – volume: 90 start-page: 439 year: 2011 end-page: 444 ident: bib0100 article-title: Risk factors for osteonecrosis of the jaws: a case-control study from the CONDOR dental PBRN publication-title: J. Dent. Res. contributor: fullname: Barasch – volume: 16 start-page: 67 year: 2009 end-page: 78 ident: bib1200 article-title: Latent bone metastasis in breast cancer tied to Src-dependent survival signals publication-title: Cancer Cell contributor: fullname: Zhang – volume: 41 start-page: 326 year: 1987 end-page: 331 ident: bib0010 article-title: The acute-phase response after bisphosphonate administration publication-title: Calcif. Tissue Int. contributor: fullname: Adami – volume: 30 start-page: 1706 year: 2011 ident: bib1240 article-title: PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization publication-title: Oncogene contributor: fullname: Zhi – volume: 89 start-page: 747 year: 1997 end-page: 754 ident: bib0285 article-title: Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation publication-title: Cell contributor: fullname: Ducy – volume: 332 start-page: 411 year: 1988 end-page: 415 ident: bib1140 article-title: A novel potent vasoconstrictor peptide produced by vascular endothelial cells publication-title: Nature contributor: fullname: Yanagisawa – volume: 16 start-page: 3376 year: 2014 ident: bib0850 article-title: Dickkopf-1 is regulated by the mevalonate pathway in breast cancer publication-title: Breast Cancer Res. contributor: fullname: Rachner – volume: 121 start-page: 4655 year: 2011 ident: bib0625 article-title: PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target publication-title: J. Clin. Invest. contributor: fullname: Li – volume: 76 start-page: 5348 year: 2016 end-page: 5360 ident: bib0500 article-title: Calcium-Sensing receptor promotes breast cancer by stimulating intracrine actions of parathyroid Hormone–related protein publication-title: Cancer Res. contributor: fullname: Kim – volume: 215 start-page: 673 year: 2009 end-page: 681 ident: bib0260 article-title: Immunohistochemical detection of estrogen receptor β in alveolar bone cells of estradiol-treated female rats: possible direct action of estrogen on osteoclast life span publication-title: J. Anat. contributor: fullname: Cerri – volume: 10 start-page: R37 year: 2008 ident: bib1195 article-title: TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood publication-title: Arthritis. Res. Ther. contributor: fullname: Zhang – volume: 154 start-page: 1060 year: 2013 end-page: 1073 ident: bib1215 article-title: Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma publication-title: Cell contributor: fullname: Zhang – start-page: 5 year: 2014 ident: bib0490 article-title: Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts publication-title: Nat. Commun. contributor: fullname: Keller – volume: 387 start-page: 641 year: 2009 end-page: 645 ident: bib0590 article-title: Identification of CITED2 as a negative regulator of fracture healing publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Lee – volume: 17 start-page: 28 year: 2015 ident: bib0630 article-title: Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models publication-title: Breast Cancer Res. contributor: fullname: Li – volume: 8 start-page: e62936 year: 2013 ident: bib1080 article-title: BSP gene silencing inhibits migration, invasion, and bone metastasis of MDA-MB-231BO human breast cancer cells publication-title: PLoS One contributor: fullname: Wang – volume: 7 start-page: 79032 year: 2016 ident: bib0995 article-title: Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells publication-title: Oncotarget contributor: fullname: Taipaleenmäki – volume: 107 start-page: 277 year: 2001 end-page: 286 ident: bib0180 article-title: Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone publication-title: J. Clin. Invest. contributor: fullname: Calvi – volume: 11 start-page: 29 year: 2011 ident: bib0465 article-title: Incidence of bone metastases and skeletal-related events in breast cancer patients: a population-based cohort study in Denmark publication-title: BMC Cancer contributor: fullname: Jensen – volume: 3 start-page: e2942 year: 2008 ident: bib0785 article-title: Control of bone mass and remodeling by PTH receptor signaling in osteocytes publication-title: PLoS One contributor: fullname: O'Brien – volume: 271 start-page: 2126 year: 1996 end-page: 2132 ident: bib0135 article-title: Human cathepsin O2: a matrix protein-degrading cysteine protease expressed in osteoclasts functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme publication-title: J. Biol. Chem. contributor: fullname: Brömme – volume: 25 start-page: 5547 year: 2006 ident: bib0210 article-title: Cited2 modulates TGF-[beta]-mediated upregulation of MMP9 publication-title: Oncogene contributor: fullname: Chou – volume: 14 start-page: 61 year: 2007 end-page: 72 ident: bib0140 article-title: Osteoblast-conditioned medium promotes proliferation and sensitizes breast cancer cells to imatinib treatment publication-title: Endocr. Relat. Cancer contributor: fullname: Brama – year: 2015 ident: bib0045 article-title: A Study to Assess the Effects of MK0822 in Reducing the Risk of Bone Metastasis in Women With Breast Cancer (0822-029) Withdrawn contributor: fullname: Anon – volume: 55 start-page: 2703 year: 1995 end-page: 2708 ident: bib0250 article-title: Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor β subunit in human breast tissue and breast carcinoma publication-title: Cancer Res. contributor: fullname: Coltrera – volume: 109 start-page: 1551 year: 2002 end-page: 1559 ident: bib0730 article-title: Blockade of TGF-β inhibits mammary tumor cell viability: migration, and metastases publication-title: J. Clin. Invest. contributor: fullname: Muraoka – volume: 61 start-page: 1255 year: 2002 end-page: 1262 ident: bib0600 article-title: Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite publication-title: Mol. Pharmacol. contributor: fullname: Lehenkari – year: 2017 ident: bib0060 article-title: Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) contributor: fullname: Anon – volume: 15 start-page: 960 year: 2009 end-page: 966 ident: bib0535 article-title: Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis publication-title: Nat. Med. contributor: fullname: Korpal – volume: 169 start-page: 681 year: 2005 end-page: 691 ident: bib0585 article-title: Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors publication-title: J. Cell Biol. contributor: fullname: Lee – volume: 315 start-page: 2072 year: 2009 end-page: 2080 ident: bib0900 article-title: Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor publication-title: Exp. Cell Res. contributor: fullname: Saidak – volume: 13 start-page: 581 year: 1998 end-page: 589 ident: bib0665 article-title: Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins: including Ras publication-title: J. Bone Miner. Res. contributor: fullname: Luckman – volume: 97 start-page: 779 year: 2003 end-page: 784 ident: bib0370 article-title: Role of endothelin-1 in osteoblastic bone metastases publication-title: Cancer contributor: fullname: Mohammad – volume: 173 start-page: 773 year: 2008 end-page: 780 ident: bib0910 article-title: Dlx5: a positive regulator of osteoblastogenesis, is essential for osteoblast-osteoclast coupling publication-title: Am. J. Pathol. contributor: fullname: Samee – volume: 6 start-page: 165 year: 1989 end-page: 177 ident: bib0075 article-title: A comparative electron microscopic study of apatite crystals in collagen fibrils of rat bone: dentin and calcified turkey leg tendons publication-title: Bone Miner. contributor: fullname: Arsenault – volume: 113 start-page: 31 year: 2009 end-page: 41 ident: bib0820 article-title: 25-Hydroxyvitamin D3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture publication-title: Breast Cancer Res. Treat. contributor: fullname: Peng – volume: 159 start-page: 87 year: 2016 end-page: 95 ident: bib0925 article-title: Phase II studies of two different schedules of dasatinib in bone metastasis predominant metastatic breast cancer: SWOG S0622 publication-title: Breast Cancer Res. Treat. contributor: fullname: Schott – volume: 113 start-page: 379 year: 2004 end-page: 389 ident: bib0960 article-title: Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways publication-title: J. Clin. Invest. contributor: fullname: Sims – volume: 14 start-page: 1399 year: 2003 end-page: 1405 ident: bib0130 article-title: Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases publication-title: Ann. Oncol. contributor: fullname: Body – volume: 4 start-page: 111 issue: 2 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib1225 article-title: Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis publication-title: Cell Metab. doi: 10.1016/j.cmet.2006.05.012 contributor: fullname: Zhao – volume: 61 start-page: 1255 issue: 5 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib0600 article-title: Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite publication-title: Mol. Pharmacol. doi: 10.1124/mol.61.5.1255 contributor: fullname: Lehenkari – volume: 15 start-page: 757 issue: 7 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib1020 article-title: TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation publication-title: Nat. Med. doi: 10.1038/nm.1979 contributor: fullname: Tang – volume: 190 start-page: 1741 issue: 12 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib0070 article-title: Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor κB (RANK) receptors publication-title: J. Exp. Med. doi: 10.1084/jem.190.12.1741 contributor: fullname: Arai – volume: 8 start-page: e62936 issue: 5 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib1080 article-title: BSP gene silencing inhibits migration, invasion, and bone metastasis of MDA-MB-231BO human breast cancer cells publication-title: PLoS One doi: 10.1371/journal.pone.0062936 contributor: fullname: Wang – volume: 24 start-page: 1361 issue: 3a year: 2004 ident: 10.1016/j.biocel.2018.01.003_bib1190 article-title: Bone sialoprotein promotes bone metastasis of a non-bone-seeking clone of human breast cancer cells publication-title: Anticancer Res. contributor: fullname: Zhang – volume: 55 start-page: 2703 issue: 12 year: 1995 ident: 10.1016/j.biocel.2018.01.003_bib0250 article-title: Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor β subunit in human breast tissue and breast carcinoma publication-title: Cancer Res. contributor: fullname: Coltrera – volume: 140 start-page: 4382 issue: 10 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib0400 article-title: Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis 1 publication-title: Endocrinology doi: 10.1210/endo.140.10.7034 contributor: fullname: Hofbauer – volume: 15 start-page: 960 issue: 8 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0535 article-title: Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis publication-title: Nat. Med. doi: 10.1038/nm.1943 contributor: fullname: Korpal – volume: 30 start-page: 1138 issue: 7 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib1055 article-title: The effects of androgens on murine cortical bone do not require AR or ERα signaling in osteoblasts and osteoclasts publication-title: J. Bone Miner. Res. doi: 10.1002/jbmr.2485 contributor: fullname: Ucer – volume: 68 start-page: 1202 issue: 7 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib1085 article-title: 1α: 25-Dihydroxyvitamin D inhibits the metastatic capability of MCF10CA1a and MDA-MB-231cells in an in vitro model of breast to bone metastasis publication-title: Nutr. Cancer doi: 10.1080/01635581.2016.1213868 contributor: fullname: Wilmanski – volume: 70 start-page: 3494 issue: 9 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0750 article-title: Matrix metalloproteinase (MMP)-13 regulates mammary Tumor–induced osteolysis by activating MMP9 and transforming growth factor-β signaling at the tumor-bone interface publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-09-3251 contributor: fullname: Nannuru – volume: 68 start-page: 7795 issue: 19 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0845 article-title: Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-08-1078 contributor: fullname: Pratap – volume: 37 start-page: 106 issue: 1 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0580 article-title: A matrix metalloproteinase inhibitor: batimastat, retards the development of osteolytic bone metastases by MDA-MB-231 human breast cancer cells in Balb C nu/nu mice publication-title: Eur. J. Cancer doi: 10.1016/S0959-8049(00)00363-4 contributor: fullname: Lee – volume: 78 start-page: 354 issue: 4 year: 1996 ident: 10.1016/j.biocel.2018.01.003_bib0160 article-title: Parathyroid hormone-related protein, bone metastases and hypercalcaemia of malignancy publication-title: Ann. R. Coll. Surg. Engl. contributor: fullname: Bundred – volume: 345 start-page: 442 issue: 6274 year: 1990 ident: 10.1016/j.biocel.2018.01.003_bib1185 article-title: The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene publication-title: Nature doi: 10.1038/345442a0 contributor: fullname: Yoshida – volume: 11 start-page: 306 issue: 1 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0610 article-title: Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.306.11.1 contributor: fullname: Lev – volume: 4 start-page: 2989 issue: 12 year: 1990 ident: 10.1016/j.biocel.2018.01.003_bib0955 article-title: Cellular signaling by peptides of the endothelin gene family publication-title: FASEB J. doi: 10.1096/fasebj.4.12.2168326 contributor: fullname: Simonson – volume: 4 start-page: e6896 issue: 9 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0300 article-title: Hypoxia and TGF-β drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment publication-title: PLoS One doi: 10.1371/journal.pone.0006896 contributor: fullname: Dunn – volume: 11 start-page: 29 issue: 1 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0465 article-title: Incidence of bone metastases and skeletal-related events in breast cancer patients: a population-based cohort study in Denmark publication-title: BMC Cancer doi: 10.1186/1471-2407-11-29 contributor: fullname: Jensen – volume: 322 start-page: 1106 issue: 16 year: 1990 ident: 10.1016/j.biocel.2018.01.003_bib0175 article-title: Immunochemical characterization of circulating parathyroid hormone–related protein in patients with humoral hypercalcemia of cancer publication-title: New Engl. J. Med. doi: 10.1056/NEJM199004193221603 contributor: fullname: Burtis – volume: 2 start-page: 1132 issue: 10 year: 1996 ident: 10.1016/j.biocel.2018.01.003_bib0430 article-title: Estrogen promotes apoptosis of murine osteoclasts mediated by TGF–β publication-title: Nat. Med. doi: 10.1038/nm1096-1132 contributor: fullname: Hughes – volume: 64 start-page: 281 issue: 1 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0695 article-title: Toxic acute tubular necrosis following treatment with zoledronate (Zometa) publication-title: Kidney Int. doi: 10.1046/j.1523-1755.2003.00071.x contributor: fullname: Markowitz – volume: 15 start-page: 1370 issue: 8 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0455 article-title: Inhibitory effects of 1α: 25-dihydroxyvitamin D3 on the G1–S phase-controlling machinery publication-title: Mol. Endocrinol. contributor: fullname: Jensen – start-page: 5 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0490 article-title: Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts publication-title: Nat. Commun. contributor: fullname: Keller – volume: 116 start-page: 1195 issue: 5 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib1165 article-title: The stem cell niches in bone publication-title: J. Clin. Invest. doi: 10.1172/JCI28568 contributor: fullname: Yin – volume: 31 issue: 15 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib0360 article-title: Denosumab versus placebo as adjuvant treatment for women with early-stage breast cancer at high risk of disease recurrence (D-CARE): an international, placebo-controlled, randomized, double-blind phase III clinical trial publication-title: J. Clin. Oncol. contributor: fullname: Goss – volume: 202 start-page: 31 issue: 1 year: 2000 ident: 10.1016/j.biocel.2018.01.003_bib0920 article-title: Expression of major bone extracellular matrix proteins during embryonic osteogenesis in rat mandibles publication-title: Anat. Embryol. (Berl.) doi: 10.1007/PL00008242 contributor: fullname: Sasano – volume: 88 start-page: 1082 issue: 5 year: 2000 ident: 10.1016/j.biocel.2018.01.003_bib0635 article-title: Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases publication-title: Cancer doi: 10.1002/(SICI)1097-0142(20000301)88:5<1082::AID-CNCR20>3.0.CO;2-Z contributor: fullname: Lipton – volume: 22 start-page: 992 issue: 7 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib1130 article-title: Induction of DC‐STAMP by alternative activation and downstream signaling mechanisms publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.070401 contributor: fullname: Yagi – volume: 7 start-page: e37624 issue: 5 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1125 article-title: Expression of dickkopf-1 and beta-catenin related to the prognosis of breast cancer patients with triple negative phenotype publication-title: PLoS One doi: 10.1371/journal.pone.0037624 contributor: fullname: Xu – volume: 8 start-page: 6169 issue: 4 year: 2017 ident: 10.1016/j.biocel.2018.01.003_bib0450 article-title: Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA publication-title: Oncotarget doi: 10.18632/oncotarget.14048 contributor: fullname: Jayaraman – volume: 8 start-page: 26687 issue: 16 year: 2017 ident: 10.1016/j.biocel.2018.01.003_bib1050 article-title: The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm publication-title: Oncotarget doi: 10.18632/oncotarget.15803 contributor: fullname: Trivedi – volume: 121 start-page: 277 issue: 1 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0515 article-title: The metabolism of 25-(OH) vitamin D 3 by osteoclasts and their precursors regulates the differentiation of osteoclasts publication-title: J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2010.03.048 contributor: fullname: Kogawa – volume: 23 start-page: 3314 issue: 15 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0520 article-title: Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: a randomized, placebo-controlled trial publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2005.05.116 contributor: fullname: Kohno – volume: 390 start-page: 175 issue: 6656 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0035 article-title: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function publication-title: Nature doi: 10.1038/36593 contributor: fullname: Anderson – volume: 17 start-page: 223 issue: 3 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0380 article-title: Healthcare costs associated with skeletal-related events in breast cancer patients with bone metastases publication-title: J. Med. Econ. doi: 10.3111/13696998.2014.890937 contributor: fullname: Hagiwara – volume: 11 start-page: 517 issue: 6 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0855 article-title: Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor publication-title: Cell Metab. doi: 10.1016/j.cmet.2010.05.005 contributor: fullname: Rauch – volume: 100 start-page: 2613 issue: 12 year: 2004 ident: 10.1016/j.biocel.2018.01.003_bib0880 article-title: Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors publication-title: Cancer doi: 10.1002/cncr.20308 contributor: fullname: Rosen – volume: 410 start-page: 50 issue: 6824 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0680 article-title: Involvement of chemokine receptors in breast cancer metastasis publication-title: Nature doi: 10.1038/35065016 contributor: fullname: Müller – volume: 169 start-page: 681 issue: 4 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0585 article-title: Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors publication-title: J. Cell Biol. doi: 10.1083/jcb.200409115 contributor: fullname: Lee – volume: 14 start-page: 730 issue: 8 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0445 article-title: CITED2 modulates breast cancer metastatic ability through effects on IKKα publication-title: Mol. Cancer Res. doi: 10.1158/1541-7786.MCR-16-0081 contributor: fullname: Jayaraman – volume: 72 start-page: 251 issue: 2 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib0935 article-title: Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors publication-title: J. Cell. Biochem. doi: 10.1002/(SICI)1097-4644(19990201)72:2<251::AID-JCB9>3.0.CO;2-W contributor: fullname: Shalhoub – volume: 67 start-page: 8742 issue: 18 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0155 article-title: Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-2490 contributor: fullname: Buijs – year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0045 contributor: fullname: Anon – volume: 89 start-page: 747 issue: 5 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0285 article-title: Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation publication-title: Cell doi: 10.1016/S0092-8674(00)80257-3 contributor: fullname: Ducy – volume: 109 start-page: 1551 issue: 12 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib0730 article-title: Blockade of TGF-β inhibits mammary tumor cell viability: migration, and metastases publication-title: J. Clin. Invest. doi: 10.1172/JCI0215234 contributor: fullname: Muraoka – volume: 18 start-page: 1095 issue: 7 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1110 article-title: Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells publication-title: Nat. Med. doi: 10.1038/nm.2793 contributor: fullname: Xian – volume: 123 start-page: 1034 issue: 5 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0150 article-title: Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases publication-title: Int. J. Cancer doi: 10.1002/ijc.23625 contributor: fullname: Bu – volume: 3 start-page: 889 issue: 6 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib1000 article-title: Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts publication-title: Dev. Cell doi: 10.1016/S1534-5807(02)00369-6 contributor: fullname: Takayanagi – volume: 287 start-page: 7169 issue: 10 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib0190 article-title: Membrane estrogen signaling enhances tumorigenesis and metastatic potential of breast cancer cells via estrogen receptor-α36 αER(36) publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.292946 contributor: fullname: Chaudhri – volume: 175 start-page: 1255 issue: 3 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0830 article-title: Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis publication-title: Am. J. Pathol. doi: 10.2353/ajpath.2009.080906 contributor: fullname: Podgorski – volume: 23 start-page: 499 issue: 6 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib1135 article-title: Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur publication-title: Bone doi: 10.1016/S8756-3282(98)00138-0 contributor: fullname: Yamaza – volume: 2 start-page: 137 issue: 4 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib0550 article-title: Incidence: consequences and treatment of bone metastases in breast cancer patients–experience from a single cancer centre publication-title: Journal of Bone Oncology doi: 10.1016/j.jbo.2013.09.001 contributor: fullname: Kuchuk – volume: 66 start-page: 4117 issue: 8 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0405 article-title: Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-05-1631 contributor: fullname: Holland – volume: 70 start-page: 6150 issue: 15 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0890 article-title: Receptor activator of NF-κB ligand enhances breast cancer–induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-09-2758 contributor: fullname: Rucci – volume: 105 start-page: 20764 issue: 52 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0815 article-title: Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.0805133106 contributor: fullname: Pederson – volume: 12 start-page: 1164 issue: 6 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0690 article-title: Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate publication-title: J. Am. Soc. Nephrol. doi: 10.1681/ASN.V1261164 contributor: fullname: Markowitz – year: 2017 ident: 10.1016/j.biocel.2018.01.003_bib0060 contributor: fullname: Anon – volume: 95 start-page: 3597 issue: 7 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib1150 article-title: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.95.7.3597 contributor: fullname: Yasuda – volume: 343 start-page: 117 issue: 1 year: 2004 ident: 10.1016/j.biocel.2018.01.003_bib0945 article-title: YY1 is involved in RANKL-induced transcription of the tartrate-resistant acid phosphatase gene in osteoclast differentiation publication-title: Gene doi: 10.1016/j.gene.2004.08.009 contributor: fullname: Shi – volume: 17 start-page: 33 issue: 1 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib0290 article-title: Transforming growth factor β1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells publication-title: Clin. Exp. Metastasis doi: 10.1023/A:1026404227624 contributor: fullname: Duivenvoorden – volume: 21 start-page: 486 issue: 2 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0220 article-title: Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation publication-title: Mol. Endocrinol. doi: 10.1210/me.2006-0346 contributor: fullname: Clines – volume: 30 start-page: 1706 issue: 14 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib1240 article-title: PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization publication-title: Oncogene doi: 10.1038/onc.2010.543 contributor: fullname: Zhi – volume: 105 start-page: 18 issue: 1 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0765 article-title: Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2 publication-title: Cancer Sci. doi: 10.1111/cas.12309 contributor: fullname: Ni – volume: 3 start-page: e2942 issue: 8 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0785 article-title: Control of bone mass and remodeling by PTH receptor signaling in osteocytes publication-title: PLoS One doi: 10.1371/journal.pone.0002942 contributor: fullname: O'Brien – volume: 208 start-page: 123 issue: 1 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib0720 article-title: A BMP-inducible gene: dlx5, regulates osteoblast differentiation and mesoderm induction publication-title: Dev. Biol. doi: 10.1006/dbio.1998.9197 contributor: fullname: Miyama – volume: 25 start-page: 8581 issue: 19 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0840 article-title: The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.25.19.8581-8591.2005 contributor: fullname: Pratap – volume: 28 start-page: 912 issue: 4 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib1005 article-title: EphrinB2/EphB4 inhibition in the osteoblast lineage modifies the anabolic response to parathyroid hormone publication-title: J. Bone Miner. Res. doi: 10.1002/jbmr.1820 contributor: fullname: Takyar – volume: 80 start-page: 1572 issue: S8 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0375 article-title: Parathyroid hormone-related protein and bone metastases publication-title: Cancer doi: 10.1002/(SICI)1097-0142(19971015)80:8+<1572::AID-CNCR7>3.0.CO;2-M contributor: fullname: Guise – volume: 7 start-page: e29862 issue: 1 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1030 article-title: An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment publication-title: PLoS One doi: 10.1371/journal.pone.0029862 contributor: fullname: Thiolloy – volume: 12 start-page: 4393 issue: 6 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0835 article-title: Cadherin-11 expression is upregulated in invasive human breast cancer publication-title: Oncol. Lett. doi: 10.3892/ol.2016.5236 contributor: fullname: Pohlodek – volume: 110 start-page: 1767 issue: 15 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0805 article-title: Endocytic pathway from the basal plasma membrane to the ruffled border membrane in bone-resorbing osteoclasts publication-title: J. Cell Sci. doi: 10.1242/jcs.110.15.1767 contributor: fullname: Palokangas – volume: 67 start-page: 5821 issue: 12 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib1230 article-title: Tumor αvβ3 integrin is a therapeutic target for breast cancer bone metastases publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-4499 contributor: fullname: Zhao – volume: 8 start-page: e66752 issue: 7 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib0570 article-title: Enpp1: a potential facilitator of breast cancer bone metastasis publication-title: PLoS One doi: 10.1371/journal.pone.0066752 contributor: fullname: Lau – volume: 125 start-page: 2028S issue: 7 year: 1995 ident: 10.1016/j.biocel.2018.01.003_bib0975 article-title: Endothelin receptors, second messengers, and actions in bone publication-title: J. Nutr. doi: 10.1093/jn/125.suppl_7.2028S contributor: fullname: Stern – volume: 271 start-page: 2126 issue: 4 year: 1996 ident: 10.1016/j.biocel.2018.01.003_bib0135 article-title: Human cathepsin O2: a matrix protein-degrading cysteine protease expressed in osteoclasts functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme publication-title: J. Biol. Chem. doi: 10.1074/jbc.271.4.2126 contributor: fullname: Brömme – volume: 108 start-page: 17 issue: 1 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib0745 article-title: The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation publication-title: Cell doi: 10.1016/S0092-8674(01)00622-5 contributor: fullname: Nakashima – year: 2017 ident: 10.1016/j.biocel.2018.01.003_bib0065 contributor: fullname: Anon – volume: 10 start-page: 625 issue: 4 year: 1995 ident: 10.1016/j.biocel.2018.01.003_bib0725 article-title: Expression and regulation of Na-Dependent pi transport in matrix vesicles produced by osteoblast-like cells publication-title: J. Bone Miner. Res. doi: 10.1002/jbmr.5650100416 contributor: fullname: Montessuit – volume: 21 start-page: 1618 issue: 10 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0090 article-title: Vitamin D action and regulation of bone remodeling: suppression of osteoclastogenesis by the mature osteoblast publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.060714 contributor: fullname: Baldock – volume: 28 start-page: 5132 issue: 35 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0985 article-title: Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2010.29.7101 contributor: fullname: Stopeck – volume: 38 start-page: 497 issue: 4 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0475 article-title: Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing publication-title: Bone doi: 10.1016/j.bone.2005.10.003 contributor: fullname: Jung – volume: 57 start-page: 5386 issue: 23 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0645 article-title: The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma publication-title: Cancer Res. contributor: fullname: Littlewood-Evans – volume: 13 start-page: 581 issue: 4 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0665 article-title: Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins: including Ras publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.1998.13.4.581 contributor: fullname: Luckman – volume: 21 start-page: 761 issue: 3 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0860 article-title: Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone publication-title: Oncol. Rep. contributor: fullname: Richert – volume: 335 start-page: 1016 issue: 14 year: 1996 ident: 10.1016/j.biocel.2018.01.003_bib0270 article-title: Esophagitis associated with the use of alendronate publication-title: New Engl. J. Med. doi: 10.1056/NEJM199610033351403 contributor: fullname: De Groen – volume: 136 issue: 5 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0330 article-title: Cancer incidence and mortality worldwide: sources methods and major patterns in GLOBOCAN 2012 publication-title: Int. J. Cancer doi: 10.1002/ijc.29210 contributor: fullname: Ferlay – volume: 282 start-page: 33098 issue: 45 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0620 article-title: Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts publication-title: J. Biol. Chem. doi: 10.1074/jbc.M611781200 contributor: fullname: Li – volume: 63 start-page: 1567 issue: 11 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0705 article-title: Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment publication-title: J. Oral Maxillofac. Surg. doi: 10.1016/j.joms.2005.07.010 contributor: fullname: Marx – volume: 335 start-page: 1785 issue: 24 year: 1996 ident: 10.1016/j.biocel.2018.01.003_bib0410 article-title: Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases publication-title: New Engl. J. Med. doi: 10.1056/NEJM199612123352401 contributor: fullname: Hortobagyi – volume: 22 start-page: 1370 issue: 6 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0990 article-title: Semaphorin 3B is a 1: 25-Dihydroxyvitamin D3-induced gene in osteoblasts that promotes osteoclastogenesis and induces osteopenia in mice publication-title: Mol. Endocrinol. doi: 10.1210/me.2007-0363 contributor: fullname: Sutton – volume: 16 start-page: 2038 issue: 6 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0415 article-title: Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate: Protocol 19 Aredia Breast Cancer Study Group publication-title: J. Clin. Oncol. doi: 10.1200/JCO.1998.16.6.2038 contributor: fullname: Hortobagyi – volume: 63 start-page: 5028 issue: 16 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0735 article-title: C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis publication-title: Cancer Res. contributor: fullname: Myoui – volume: 16 start-page: 458 issue: 6 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0950 article-title: Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis publication-title: Breast Cancer Res.: BCR doi: 10.1186/s13058-014-0458-y contributor: fullname: Siclari – volume: 67 start-page: 9894 issue: 20 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0575 article-title: A Cathepsin K inhibitor reduces breast cancer–induced osteolysis and skeletal tumor burden publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-3940 contributor: fullname: Le Gall – volume: 253 start-page: 395 issue: 2 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0740 article-title: RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis publication-title: Biochem. Biophys. Res. Commun. doi: 10.1006/bbrc.1998.9788 contributor: fullname: Nakagawa – volume: 298 start-page: 843 issue: 5594 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib0545 article-title: Reversal of bone loss in mice by nongenotropic signaling of sex steroids publication-title: Science doi: 10.1126/science.1074935 contributor: fullname: Kousteni – volume: 10 start-page: 452 issue: 6 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0460 article-title: The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial publication-title: Clin. Breast Cancer doi: 10.3816/CBC.2010.n.059 contributor: fullname: Jensen – volume: 62 start-page: 917 issue: 3 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib1160 article-title: Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer publication-title: Cancer Res. contributor: fullname: Yi – volume: 27 start-page: 165 issue: 3 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0245 article-title: Metastatic bone disease: clinical features, pathophysiology and treatment strategies publication-title: Cancer Treatment Rev. doi: 10.1053/ctrv.2000.0210 contributor: fullname: Coleman – volume: 100 start-page: 10954 issue: 19 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib1175 article-title: A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.1830978100 contributor: fullname: Yin – volume: 121 start-page: 4655 issue: 12 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0625 article-title: PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target publication-title: J. Clin. Invest. doi: 10.1172/JCI46134 contributor: fullname: Li – volume: 113 start-page: 31 issue: 1 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0820 article-title: 25-Hydroxyvitamin D3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture publication-title: Breast Cancer Res. Treat. doi: 10.1007/s10549-008-9900-0 contributor: fullname: Peng – volume: 278 start-page: 22023 issue: 24 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib1045 article-title: From lysosomes to the plasma membrane localization of vacuolar type H+−ATPase with the a3 isoform during osteoclast differentiation publication-title: J. Biol. Chem. doi: 10.1074/jbc.M302436200 contributor: fullname: Toyomura – volume: 277 start-page: 24571 issue: 27 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib0480 article-title: Transforming growth factor-β stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways publication-title: J. Biol. Chem. doi: 10.1074/jbc.M202561200 contributor: fullname: Käkönen – volume: 386 start-page: 81 issue: 6620 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib1040 article-title: Osteopetrosis in mice lacking haematopoietic transcription factor PU . 1 publication-title: Nature doi: 10.1038/386081a0 contributor: fullname: Tondravi – volume: 48 start-page: S17 issue: 1 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0020 article-title: A phase II, randomized, open-label, pilot study to evaluate the safety and the effects on bone resorption of saracatinib (AZD0530) in patients with prostate cancer or breast cancer with metastatic bone disease publication-title: Bone doi: 10.1016/j.bone.2010.10.044 contributor: fullname: Aklilu – volume: 5 start-page: 1001 issue: 10 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0875 article-title: Osteoactivin promotes breast cancer metastasis to bone publication-title: Mol. Cancer Res. doi: 10.1158/1541-7786.MCR-07-0119 contributor: fullname: Rose – volume: 13 start-page: R105 issue: 5 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0825 article-title: MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases publication-title: Breast Cancer Res. doi: 10.1186/bcr3047 contributor: fullname: Pivetta – volume: 72 start-page: 4238 issue: 16 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib0395 article-title: Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-11-3061 contributor: fullname: Hiraga – volume: 99 start-page: 1901 issue: 6 year: 1984 ident: 10.1016/j.biocel.2018.01.003_bib0170 article-title: Osteoclast formation from mononuclear phagocytes: role of bone-forming cells publication-title: J. Cell Biol. doi: 10.1083/jcb.99.6.1901 contributor: fullname: Burger – volume: 21 start-page: 1924 issue: 12 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0425 article-title: Calcitonin deficiency in mice progressively results in high bone turnover publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.060820 contributor: fullname: Huebner – volume: 118 start-page: 5479 issue: 23 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib1145 article-title: NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP publication-title: J. Cell Sci. doi: 10.1242/jcs.02655 contributor: fullname: Yaroslavskiy – year: 2017 ident: 10.1016/j.biocel.2018.01.003_bib0055 contributor: fullname: Anon – volume: 23 start-page: 1157 issue: 4 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0810 article-title: Pain outcomes in patients with bone metastases from advanced cancer: assessment and management with bone-targeting agents publication-title: Support. Care Cancer doi: 10.1007/s00520-014-2525-4 contributor: fullname: Patrick – volume: 1 start-page: 11 issue: 1 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib1120 article-title: Osteoclasts: new insights publication-title: Bone. Res. doi: 10.4248/BR201301003 contributor: fullname: Xu – volume: 7 start-page: e39871 issue: 7 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib0770 article-title: Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation publication-title: PLoS One doi: 10.1371/journal.pone.0039871 contributor: fullname: Nicolaidou – volume: 191 start-page: 39 issue: 1 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0085 article-title: Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone publication-title: J. Anat. doi: 10.1046/j.1469-7580.1997.19110039.x contributor: fullname: BORD – volume: 215 start-page: 673 issue: 6 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0260 article-title: Immunohistochemical detection of estrogen receptor β in alveolar bone cells of estradiol-treated female rats: possible direct action of estrogen on osteoclast life span publication-title: J. Anat. doi: 10.1111/j.1469-7580.2009.01158.x contributor: fullname: Cruzoé-Souza – volume: 41 start-page: 59 issue: 1 year: 1969 ident: 10.1016/j.biocel.2018.01.003_bib0040 article-title: Vesicles associated with calcification in the matrix of epiphyseal cartilage publication-title: J. Cell Biol. doi: 10.1083/jcb.41.1.59 contributor: fullname: Anderson – volume: 66 start-page: 6714 issue: 13 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0095 article-title: Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-β type I receptor kinase inhibitor publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-05-3565 contributor: fullname: Bandyopadhyay – volume: 7 start-page: 79688 issue: 48 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib1015 article-title: Breast cancer cells obtain an osteomimetic feature via epithelial-mesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction publication-title: Oncotarget doi: 10.18632/oncotarget.12939 contributor: fullname: Tan – volume: 300 start-page: 957 issue: 4 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0795 article-title: Role of prostaglandin E produced by osteoblasts in osteolysis due to bone metastasis publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/S0006-291X(02)02937-6 contributor: fullname: Ohshiba – volume: 11 start-page: 1779 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0980 article-title: Hypercalcemia of malignancy and new treatment options publication-title: Ther. Clin. Risk Manage. contributor: fullname: Sternlicht – volume: 6 start-page: 165 issue: 2 year: 1989 ident: 10.1016/j.biocel.2018.01.003_bib0075 article-title: A comparative electron microscopic study of apatite crystals in collagen fibrils of rat bone: dentin and calcified turkey leg tendons publication-title: Bone Miner. doi: 10.1016/0169-6009(89)90048-2 contributor: fullname: Arsenault – volume: 187 start-page: 218 issue: 2 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0510 article-title: Endothelin-1 expression in long-term cultures of fetal rat calvarial osteoblasts: regulation by BMP-7 publication-title: Journal of Cellular Physiology doi: 10.1002/jcp.1072 contributor: fullname: Kitten – volume: 8 start-page: 739 issue: 5 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0265 article-title: Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis publication-title: Dev. Cell doi: 10.1016/j.devcel.2005.03.016 contributor: fullname: Day – volume: 70 start-page: 1835 issue: 5 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0800 article-title: Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-09-3194 contributor: fullname: Ooi – volume: 7 start-page: 280 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0700 article-title: Prevention of bone loss in a model of postmenopausal osteoporosis through adrenomedullin inhibition publication-title: Front. Physiol. doi: 10.3389/fphys.2016.00280 contributor: fullname: Martínez-Herrero – volume: 173 start-page: 773 issue: 3 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0910 article-title: Dlx5: a positive regulator of osteoblastogenesis, is essential for osteoblast-osteoclast coupling publication-title: Am. J. Pathol. doi: 10.2353/ajpath.2008.080243 contributor: fullname: Samee – volume: 49 start-page: 623 issue: 4 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0605 article-title: The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking publication-title: Bone doi: 10.1016/j.bone.2011.06.014 contributor: fullname: Leung – volume: 6 start-page: e27090 issue: 11 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0125 article-title: Anti-transforming growth factor ss antibody treatment rescues bone loss and prevents breast cancer metastasis to bone publication-title: PLoS One doi: 10.1371/journal.pone.0027090 contributor: fullname: Biswas – volume: 21 start-page: 327 issue: 2 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0780 article-title: Different molecular profiles are associated with breast cancer cell homing compared with colonisation of bone: evidence using a novel bone-seeking cell line publication-title: Endocr. Relat. Cancer doi: 10.1530/ERC-13-0158 contributor: fullname: Nutter – volume: 3 start-page: e3537 issue: 10 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0915 article-title: Osteoclasts control osteoblast chemotaxis via PDGF-BB/PDGF receptor beta signaling publication-title: PLoS One doi: 10.1371/journal.pone.0003537 contributor: fullname: Sanchez-Fernandez – volume: 120 start-page: 549 issue: 7 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1210 article-title: c-Src expression is predictive of poor prognosis in breast cancer patients with bone metastasis: but not in patients with visceral metastasis publication-title: APMIS doi: 10.1111/j.1600-0463.2011.02864.x contributor: fullname: Zhang – volume: 296 start-page: 235 issue: 2 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0295 article-title: Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates publication-title: J. Pharmacol. Exp. Ther. contributor: fullname: Dunford – volume: 140 start-page: 4451 issue: 10 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib1035 article-title: Breast cancer cells interact with osteoblasts to support osteoclast formation 1 publication-title: Endocrinology doi: 10.1210/endo.140.10.7037 contributor: fullname: Thomas – volume: 23 start-page: 2025 issue: 12 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib1070 article-title: Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.080706 contributor: fullname: Walker – volume: 29 start-page: 1221 issue: 9 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib1060 article-title: American Society of Clinical Oncology executive summary of the clinical practice guideline update on the role of bone-modifying agents in metastatic breast cancer publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2010.32.5209 contributor: fullname: Van Poznak – volume: 128 start-page: 1253 issue: 8 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0145 article-title: Inactivation of the (β)-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development publication-title: Development doi: 10.1242/dev.128.8.1253 contributor: fullname: Brault – volume: 78 start-page: 205 issue: 2 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib1090 article-title: Estradiol enhances osteolytic lesions in mice inoculated with human estrogen receptor-negative MDA-231 breast cancer cells in vivo publication-title: Breast Cancer Res. Treat. doi: 10.1023/A:1022943127689 contributor: fullname: Winding – volume: 63 start-page: 2631 issue: 10 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0105 article-title: Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells publication-title: Cancer Res. contributor: fullname: Barnes – volume: 583 start-page: 2435 issue: 14 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0970 article-title: Regulatory mechanism of NFATc1 in RANKL‐induced osteoclast activation publication-title: FEBS Lett. doi: 10.1016/j.febslet.2009.06.047 contributor: fullname: Song – volume: 16 start-page: 1486 issue: 8 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib1180 article-title: A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.2001.16.8.1486 contributor: fullname: Yoneda – volume: 130 start-page: 1401 issue: 3 year: 1992 ident: 10.1016/j.biocel.2018.01.003_bib0185 article-title: Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex publication-title: Endocrinology contributor: fullname: Campbell – volume: 19 start-page: 1059 issue: 7 year: 2004 ident: 10.1016/j.biocel.2018.01.003_bib0110 article-title: A single-dose placebo-controlled study of AMG 162: a fully human monoclonal antibody to RANKL, in postmenopausal women publication-title: J. Bone Miner. Res. doi: 10.1359/JBMR.040305 contributor: fullname: Bekker – volume: 101 start-page: 6158 issue: 16 year: 2004 ident: 10.1016/j.biocel.2018.01.003_bib0675 article-title: The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0401602101 contributor: fullname: Mócsai – volume: 125 start-page: 971 issue: 5 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0280 article-title: SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation publication-title: Cell doi: 10.1016/j.cell.2006.05.012 contributor: fullname: Dobreva – volume: 269 start-page: 25742 issue: 41 year: 1994 ident: 10.1016/j.biocel.2018.01.003_bib0340 article-title: Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(18)47310-3 contributor: fullname: Fowlkes – volume: 107 start-page: 277 issue: 3 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0180 article-title: Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone publication-title: J. Clin. Invest. doi: 10.1172/JCI11296 contributor: fullname: Calvi – volume: 102 start-page: 881 issue: 5 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0305 article-title: PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha (v) beta3 integrin, and phosphorylated by src kinase publication-title: J. Clin. Invest. doi: 10.1172/JCI3212 contributor: fullname: Duong – volume: 70 start-page: 6537 issue: 16 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0225 article-title: Anti–placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-09-4092 contributor: fullname: Coenegrachts – volume: 3 start-page: 395 issue: 2 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1205 article-title: C-Src-mediated RANKL-induced breast cancer cell migration by activation of the ERK and Akt pathway publication-title: Oncology Letters doi: 10.3892/ol.2011.487 contributor: fullname: Zhang – volume: 89 start-page: 771 issue: 4 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0505 article-title: Vitamin D3 supports osteoclastogenesis via functional vitamin D response element of human RANKL gene promoter publication-title: J. Cell. Biochem. doi: 10.1002/jcb.10567 contributor: fullname: Kitazawa – year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib1010 article-title: Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone publication-title: Int. J. Oncol. doi: 10.3892/ijo.33.1.17 contributor: fullname: Tamura – volume: 387 start-page: 641 issue: 4 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0590 article-title: Identification of CITED2 as a negative regulator of fracture healing publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2009.07.029 contributor: fullname: Lee – volume: 332 start-page: 411 issue: 6163 year: 1988 ident: 10.1016/j.biocel.2018.01.003_bib1140 article-title: A novel potent vasoconstrictor peptide produced by vascular endothelial cells publication-title: Nature doi: 10.1038/332411a0 contributor: fullname: Yanagisawa – volume: 314 start-page: 2334 issue: 13 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0005 article-title: Osteoactivin: an anabolic factor that regulates osteoblast differentiation and function publication-title: Exp. Cell Res. doi: 10.1016/j.yexcr.2008.02.006 contributor: fullname: Abdelmagid – volume: 89 start-page: 755 issue: 5 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0525 article-title: Targeted disruption of Cbfa1results in a complete lack of bone formation owing to maturational arrest of osteoblasts publication-title: Cell doi: 10.1016/S0092-8674(00)80258-5 contributor: fullname: Komori – volume: 1843 start-page: 815 issue: 4 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0115 article-title: Microenvironmental stimuli affect Endothelin-1 signaling responsible for invasiveness and osteomimicry of bone metastasis from breast cancer publication-title: Biochim. et Biophys. Acta (BBA)-Mol. Cell Res. doi: 10.1016/j.bbamcr.2013.12.015 contributor: fullname: Bendinelli – volume: 25 start-page: 4431 issue: 28 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0640 article-title: Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2007.11.8604 contributor: fullname: Lipton – volume: 67 start-page: 9542 issue: 19 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib1235 article-title: Accelerated bone resorption: due to dietary calcium deficiency, promotes breast cancer tumor growth in bone publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-07-1046 contributor: fullname: Zheng – volume: 107 start-page: 1118 issue: 6 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0355 article-title: Bone sialoprotein stimulates focal adhesion-related signaling pathways: role in migration and survival of breast and prostate cancer cells publication-title: J. Cell. Biochem. doi: 10.1002/jcb.22211 contributor: fullname: Gordon – volume: 17 start-page: 1473 issue: 11 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0755 article-title: Suppression of bone formation by osteoclastic expression of semaphorin 4D publication-title: Nat. Med. doi: 10.1038/nm.2489 contributor: fullname: Negishi-Koga – volume: 22 start-page: 5706 issue: 23 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0715 article-title: TBCRC-010: phase I/II study of dasatinib in combination with zoledronic acid for the treatment of Breast cancer bone metastasis publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-15-2845 contributor: fullname: Mitri – start-page: djs485 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib0325 article-title: Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1 publication-title: J. Natl. Cancer Inst. contributor: fullname: Fang – volume: 14 start-page: 61 issue: 1 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0140 article-title: Osteoblast-conditioned medium promotes proliferation and sensitizes breast cancer cells to imatinib treatment publication-title: Endocr. Relat. Cancer doi: 10.1677/erc.1.01307 contributor: fullname: Brama – volume: 458 start-page: 524 issue: 7237 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0435 article-title: Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis publication-title: Nature doi: 10.1038/nature07713 contributor: fullname: Ishii – volume: 5 start-page: 587 issue: 6 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0390 article-title: Clinical and autopsy findings in spinal cord compression due to metastatic disease publication-title: Eur. J. Neurol. doi: 10.1046/j.1468-1331.1998.560587.x contributor: fullname: Helweg-Larsen – volume: 103 start-page: 197 issue: 2 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib1170 article-title: TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development publication-title: J. Clin. Invest. doi: 10.1172/JCI3523 contributor: fullname: Yin – volume: 372 start-page: 92 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0255 article-title: NFATc1 regulation of the human β3 integrin promoter in osteoclast differentiation publication-title: Gene doi: 10.1016/j.gene.2005.12.012 contributor: fullname: Crotti – volume: 343 start-page: 289 issue: 2 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0760 article-title: Osteoblast physiology in normal and pathological conditions publication-title: Cell Tissue Res. doi: 10.1007/s00441-010-1086-1 contributor: fullname: Neve – volume: 43 start-page: 89 issue: 2 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0595 article-title: Implications of bone-only metastases in breast cancer: favorable preference with excellent outcomes of hormone receptor positive breast cancer publication-title: Cancer Research and Treatment doi: 10.4143/crt.2011.43.2.89 contributor: fullname: Lee – volume: 190 start-page: 293 issue: 2 year: 1999 ident: 10.1016/j.biocel.2018.01.003_bib0775 article-title: Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption publication-title: J. Exp. Med. doi: 10.1084/jem.190.2.293 contributor: fullname: Niida – volume: 303 start-page: 303 issue: 1 year: 1994 ident: 10.1016/j.biocel.2018.01.003_bib0870 article-title: Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum publication-title: Biochem. J doi: 10.1042/bj3030303 contributor: fullname: Rogers – volume: 16 start-page: 67 issue: 1 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib1200 article-title: Latent bone metastasis in breast cancer tied to Src-dependent survival signals publication-title: Cancer Cell doi: 10.1016/j.ccr.2009.05.017 contributor: fullname: Zhang – volume: 97 start-page: 779 issue: S3 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0370 article-title: Role of endothelin-1 in osteoblastic bone metastases publication-title: Cancer doi: 10.1002/cncr.11129 contributor: fullname: Guise – volume: 116 start-page: 1230 issue: 5 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0685 article-title: Placental growth factor mediates mesenchymal cell development: cartilage turnover, and bone remodeling during fracture repair publication-title: J. Clin. Invest. doi: 10.1172/JCI26772 contributor: fullname: Maes – volume: 386 start-page: 433 issue: 9992 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0345 article-title: Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(15)60995-3 contributor: fullname: Gnant – year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0655 contributor: fullname: Llombart – volume: 98 start-page: 1544 issue: 7 year: 1996 ident: 10.1016/j.biocel.2018.01.003_bib0365 article-title: Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis publication-title: J. Clin. Invest. doi: 10.1172/JCI118947 contributor: fullname: Guise – volume: 13 start-page: 2898 issue: 12 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0310 article-title: Efficacy of a cathepsin K inhibitor in a preclinical model for prevention and treatment of breast cancer bone metastasis publication-title: Mol. Cancer Ther. doi: 10.1158/1535-7163.MCT-14-0253 contributor: fullname: Duong – volume: 38 start-page: 427 issue: 4 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0385 article-title: Incidence of bone metastases and survival after a diagnosis of bone metastases in breast cancer patients publication-title: Cancer Epidemiol. doi: 10.1016/j.canep.2014.05.005 contributor: fullname: Harries – volume: 104 start-page: 719 issue: 5 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0540 article-title: Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity publication-title: Cell contributor: fullname: Kousteni – volume: 67 start-page: 1513 issue: 3 year: 1970 ident: 10.1016/j.biocel.2018.01.003_bib0030 article-title: Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.67.3.1513 contributor: fullname: Ali – volume: 113 start-page: 379 issue: 3 year: 2004 ident: 10.1016/j.biocel.2018.01.003_bib0960 article-title: Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways publication-title: J. Clin. Invest. doi: 10.1172/JCI19872 contributor: fullname: Sims – volume: 315 start-page: 2072 issue: 12 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0900 article-title: Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor publication-title: Exp. Cell Res. doi: 10.1016/j.yexcr.2009.03.003 contributor: fullname: Saidak – volume: 120 start-page: 582 issue: 2 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib1075 article-title: Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice publication-title: J. Clin. Invest. doi: 10.1172/JCI40568 contributor: fullname: Walker – year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0050 contributor: fullname: Anon – volume: 89 start-page: 1927 issue: 10 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0790 article-title: Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6601397 contributor: fullname: Oehler – volume: 119 start-page: 1519 issue: 7 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib1105 article-title: The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma publication-title: Int. J. Cancer doi: 10.1002/ijc.21865 contributor: fullname: Wu – volume: 21 start-page: 456 issue: 3 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib1220 article-title: Pharmacological sequestration of intracellular cholesterol in late endosomes disrupts ruffled border formation in osteoclasts publication-title: J. Bone Miner. Res. doi: 10.1359/JBMR.051204 contributor: fullname: Zhao – volume: 157 start-page: 528 issue: 3 year: 1993 ident: 10.1016/j.biocel.2018.01.003_bib1155 article-title: Plasminogen-dependent activation of latent transforming growth factor beta (TGFβ) by growing cultures of osteoblast-like cells publication-title: J. Cell. Physiol. doi: 10.1002/jcp.1041570312 contributor: fullname: Yee – volume: 80 start-page: 1588 issue: S8 year: 1997 ident: 10.1016/j.biocel.2018.01.003_bib0240 article-title: Skeletal complications of malignancy publication-title: Cancer doi: 10.1002/(SICI)1097-0142(19971015)80:8+<1588::AID-CNCR9>3.0.CO;2-G contributor: fullname: Coleman – volume: 90 start-page: 439 issue: 4 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0100 article-title: Risk factors for osteonecrosis of the jaws: a case-control study from the CONDOR dental PBRN publication-title: J. Dent. Res. doi: 10.1177/0022034510397196 contributor: fullname: Barasch – volume: 77 start-page: 336 issue: 2 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0230 article-title: Clinical course and prognostic factors following bone recurrence from breast cancer publication-title: Br. J. Cancer doi: 10.1038/bjc.1998.52 contributor: fullname: Coleman – volume: 159 start-page: 87 issue: 1 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0925 article-title: Phase II studies of two different schedules of dasatinib in bone metastasis predominant metastatic breast cancer: SWOG S0622 publication-title: Breast Cancer Res. Treat. doi: 10.1007/s10549-016-3911-z contributor: fullname: Schott – volume: 40 start-page: 1517 issue: 6 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0080 article-title: Metabolism of vitamin D 3 in human osteoblasts: evidence for autocrine and paracrine activities of 1α, 25-dihydroxyvitamin D 3 publication-title: Bone doi: 10.1016/j.bone.2007.02.024 contributor: fullname: Atkins – volume: 14 start-page: 1099 issue: 2 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0650 article-title: Immunolocalization of MMP9 and MMP2 in osteolytic metastasis originating from MDA-MB-231 human breast cancer cells publication-title: Mol. Med. Rep. doi: 10.3892/mmr.2016.5374 contributor: fullname: Liu – volume: 154 start-page: 1060 issue: 5 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib1215 article-title: Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma publication-title: Cell doi: 10.1016/j.cell.2013.07.036 contributor: fullname: Zhang – volume: 10 start-page: R37 issue: 2 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib1195 article-title: TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood publication-title: Arthritis. Res. Ther. doi: 10.1186/ar2391 contributor: fullname: Zhang – volume: 290 start-page: 6903 issue: 11 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0905 article-title: Wnt/β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cells publication-title: J. Biol. Chem. doi: 10.1074/jbc.M114.621219 contributor: fullname: Saidak – volume: 123 start-page: 666 issue: 2 year: 2013 ident: 10.1016/j.biocel.2018.01.003_bib0660 article-title: Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation publication-title: J. Clin. Invest. contributor: fullname: Lotinun – volume: 286 start-page: 42575 issue: 49 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0200 article-title: Regulation of breast cancer-induced bone lesions by β-catenin protein signaling publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.294595 contributor: fullname: Chen – year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1100 contributor: fullname: Wong – volume: 94 start-page: 560 issue: 2 year: 1994 ident: 10.1016/j.biocel.2018.01.003_bib0420 article-title: Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta publication-title: J. Clin. Invest. doi: 10.1172/JCI117370 contributor: fullname: Huang – volume: 318 start-page: 161 issue: 1 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0885 article-title: Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.106.102004 contributor: fullname: Rucci – volume: 7 start-page: 79032 issue: 48 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0995 article-title: Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells publication-title: Oncotarget doi: 10.18632/oncotarget.12593 contributor: fullname: Taipaleenmäki – volume: 107 start-page: 1898 issue: 12 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0710 article-title: CITED2 in breast carcinoma as a potent prognostic predictor associated with proliferation: migration and chemoresistance publication-title: Cancer Sci. doi: 10.1111/cas.13081 contributor: fullname: Minemura – volume: 443 start-page: 694 issue: 2 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0470 article-title: A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2013.12.036 contributor: fullname: Jensen – volume: 31 start-page: 529 issue: 4 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib1065 article-title: Morphological: histomorphometric, and microstructural alterations in human bone metastasis from breast carcinoma publication-title: Bone doi: 10.1016/S8756-3282(02)00847-5 contributor: fullname: Vukmirovic-Popovic – volume: 386 start-page: 1353 issue: 10001 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0315 article-title: Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(15)60908-4 contributor: fullname: E.B.C.T.C. Group – volume: 17 start-page: 28 issue: 1 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0630 article-title: Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models publication-title: Breast Cancer Res. doi: 10.1186/s13058-015-0537-8 contributor: fullname: Li – volume: 97 start-page: 7829 issue: 14 year: 2000 ident: 10.1016/j.biocel.2018.01.003_bib0940 article-title: Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.130200197 contributor: fullname: Shevde – volume: 286 start-page: 32995 issue: 38 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib1025 article-title: Osteoblast-specific transcription factor Osterix (Osx) is an upstream regulator of Satb2 during bone formation publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.244236 contributor: fullname: Tang – volume: 216 start-page: 35 issue: 1 year: 1995 ident: 10.1016/j.biocel.2018.01.003_bib0670 article-title: The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization publication-title: Exp. Cell Res. doi: 10.1006/excr.1995.1005 contributor: fullname: Lynch – volume: 156 start-page: 1604 issue: 6 year: 1982 ident: 10.1016/j.biocel.2018.01.003_bib0165 article-title: In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes publication-title: J. Exp. Med. doi: 10.1084/jem.156.6.1604 contributor: fullname: Burger – volume: 25 start-page: 5547 issue: 40 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0210 article-title: Cited2 modulates TGF-[beta]-mediated upregulation of MMP9 publication-title: Oncogene doi: 10.1038/sj.onc.1209552 contributor: fullname: Chou – volume: 23 start-page: 279 issue: 3 year: 2002 ident: 10.1016/j.biocel.2018.01.003_bib0865 article-title: Sex steroids and the construction and conservation of the adult skeleton publication-title: Endocr. Rev. doi: 10.1210/edrv.23.3.0465 contributor: fullname: Riggs – volume: 104 start-page: 205 issue: 2 year: 2001 ident: 10.1016/j.biocel.2018.01.003_bib0530 article-title: Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man publication-title: Cell doi: 10.1016/S0092-8674(01)00206-9 contributor: fullname: Kornak – volume: 15 start-page: 997 issue: 9 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0235 article-title: Adjuvant zoledronic acid in patients with early breast cancer: final efficacy analysis of the AZURE (BIG 01/04) randomised open-label phase 3 trial publication-title: Lancet Oncol. doi: 10.1016/S1470-2045(14)70302-X contributor: fullname: Coleman – volume: 3 start-page: 537 issue: 6 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0485 article-title: A multigenic program mediating breast cancer metastasis to bone publication-title: Cancer Cell doi: 10.1016/S1535-6108(03)00132-6 contributor: fullname: Kang – volume: 27 start-page: 1564 issue: 10 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0335 article-title: Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer: breast cancer, or other neoplasms after intravenous bisphosphonates publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2008.19.2146 contributor: fullname: Fizazi – volume: 119 start-page: 1776 issue: 4 year: 1986 ident: 10.1016/j.biocel.2018.01.003_bib0120 article-title: 1, 25-Dihydroxyvitamin D3 and human bone-derived cells in vitro: effects on alkaline phosphatase, type I collagen and proliferation publication-title: Endocrinology doi: 10.1210/endo-119-4-1776 contributor: fullname: Beresford – volume: 22 start-page: 176 issue: 1 year: 2008 ident: 10.1016/j.biocel.2018.01.003_bib0495 article-title: NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP) publication-title: Mol. Endocrinol. doi: 10.1210/me.2007-0237 contributor: fullname: Kim – volume: 16 start-page: 3376 issue: 1 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0850 article-title: Dickkopf-1 is regulated by the mevalonate pathway in breast cancer publication-title: Breast Cancer Res. doi: 10.1186/bcr3616 contributor: fullname: Rachner – volume: 126 start-page: 876 issue: 4 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0565 article-title: Identification of prospective factors promoting osteotropism in breast cancer: a potential role for CITED2 publication-title: Int. J. Cancer doi: 10.1002/ijc.24780 contributor: fullname: Lau – volume: 26 start-page: 1594 issue: 7 year: 2012 ident: 10.1016/j.biocel.2018.01.003_bib1095 article-title: Hematopoietic stem cell mobilizing agents G-CSF: cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation publication-title: Leukemia doi: 10.1038/leu.2012.17 contributor: fullname: Winkler – volume: 41 start-page: 326 issue: 6 year: 1987 ident: 10.1016/j.biocel.2018.01.003_bib0010 article-title: The acute-phase response after bisphosphonate administration publication-title: Calcif. Tissue Int. doi: 10.1007/BF02556671 contributor: fullname: Adami – volume: 333 start-page: 356 issue: 6 year: 1995 ident: 10.1016/j.biocel.2018.01.003_bib0615 article-title: Endothelins publication-title: New Engl. J. Med. doi: 10.1056/NEJM199508103330607 contributor: fullname: Levin – volume: 76 start-page: 5348 issue: 18 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0500 article-title: Calcium-Sensing receptor promotes breast cancer by stimulating intracrine actions of parathyroid Hormone–related protein publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-15-2614 contributor: fullname: Kim – volume: 26 start-page: 3789 issue: 26 year: 2007 ident: 10.1016/j.biocel.2018.01.003_bib0965 article-title: COX-2 involvement in breast cancer metastasis to bone publication-title: Oncogene doi: 10.1038/sj.onc.1210154 contributor: fullname: Singh – volume: 14 start-page: 1399 issue: 9 year: 2003 ident: 10.1016/j.biocel.2018.01.003_bib0130 article-title: Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases publication-title: Ann. Oncol. doi: 10.1093/annonc/mdg367 contributor: fullname: Body – volume: 17 start-page: 173 issue: 3 year: 2015 ident: 10.1016/j.biocel.2018.01.003_bib0320 article-title: Differences of osteoblastic bone metastases and osteolytic bone metastases in clinical features and molecular characteristics publication-title: Clin. Trans. Oncol. doi: 10.1007/s12094-014-1247-x contributor: fullname: Fang – volume: 335 start-page: 437 issue: 2 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0555 article-title: The hematopoietic transcription factor PU: 1 regulates RANK gene expression in myeloid progenitors publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2005.07.092 contributor: fullname: Kwon – volume: 92 start-page: 1531 issue: 8 year: 2005 ident: 10.1016/j.biocel.2018.01.003_bib0025 article-title: Vascular endothelial growth factor acts as an osteolytic factor in breast cancer metastases to bone publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6602417 contributor: fullname: Aldridge – volume: 24 start-page: 3557 issue: 8 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib0215 article-title: Burden of symptoms associated with development of metastatic bone disease in patients with breast cancer publication-title: Support. Care Cancer doi: 10.1007/s00520-016-3154-x contributor: fullname: Cleeland – volume: 48 start-page: S17 issue: 1 year: 2011 ident: 10.1016/j.biocel.2018.01.003_bib0015 article-title: A phase II, randomized, open-label, pilot study to evaluate the safety and the effects on bone resorption of saracatinib (AZD0530) in patients with prostate cancer or breast cancer with metastatic bone disease publication-title: Bone doi: 10.1016/j.bone.2010.10.044 contributor: fullname: Aklilu – volume: 15 start-page: 97 issue: 1 year: 2017 ident: 10.1016/j.biocel.2018.01.003_bib0205 article-title: Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers publication-title: J. Transl. Med. doi: 10.1186/s12967-017-1192-x contributor: fullname: Chiu – volume: 207 start-page: 2793 issue: 13 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0440 article-title: Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo publication-title: J. Exp. Med. doi: 10.1084/jem.20101474 contributor: fullname: Ishii – volume: 6 start-page: 32804 year: 2016 ident: 10.1016/j.biocel.2018.01.003_bib1115 article-title: CD147/EMMPRIN overexpression and prognosis in cancer: a systematic review and meta-analysis publication-title: Sci. Rep. doi: 10.1038/srep32804 contributor: fullname: Xin – volume: 12 start-page: 215 issue: 6 year: 2010 ident: 10.1016/j.biocel.2018.01.003_bib0195 article-title: Breast cancer metastasis to the bone: mechanisms of bone loss publication-title: Breast Cancer Res. doi: 10.1186/bcr2781 contributor: fullname: Chen – volume: 265 start-page: 1573 issue: 5178 year: 1994 ident: 10.1016/j.biocel.2018.01.003_bib0930 article-title: Requirement of transcription factor PU: 1 in the development of multiple hematopoietic lineages publication-title: Science doi: 10.1126/science.8079170 contributor: fullname: Scott – volume: 17 start-page: 4456 issue: 15 year: 1998 ident: 10.1016/j.biocel.2018.01.003_bib0275 article-title: PU. 1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors publication-title: EMBO J. doi: 10.1093/emboj/17.15.4456 contributor: fullname: DeKoter – volume: 27 start-page: 3757 issue: 23 year: 2009 ident: 10.1016/j.biocel.2018.01.003_bib0350 article-title: Prognostic effects of 25-hydroxyvitamin D levels in early breast cancer publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2008.20.0725 contributor: fullname: Goodwin – volume: 25 start-page: 5840 issue: 24 year: 2006 ident: 10.1016/j.biocel.2018.01.003_bib0895 article-title: Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast–osteoblast coupling publication-title: EMBO J. doi: 10.1038/sj.emboj.7601430 contributor: fullname: Ryu – volume: 3 start-page: 328 issue: 1 year: 2014 ident: 10.1016/j.biocel.2018.01.003_bib0560 article-title: Health resource utilization associated with skeletal-related events in patients with advanced breast cancer: results from a prospective, multinational observational study publication-title: SpringerPlus doi: 10.1186/2193-1801-3-328 contributor: fullname: Lüftner |
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| Snippet | Breast cancer is the most common cancer affecting women worldwide, with bone metastases presenting as the most common site of disease recurrence. Bone... |
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| SubjectTerms | Bone metastases Bone Neoplasms - metabolism Bone Neoplasms - pathology Bone Neoplasms - secondary Bone Neoplasms - therapy Bone Remodeling Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Breast Neoplasms - therapy Female Humans Neoplasm Metastasis Osteoblastic lesions Osteolysis Osteomimicry Targeted therapies |
| Title | Breast cancer bone metastases: pathogenesis and therapeutic targets |
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