Mixed Langerhans cell and interstitial/dermal dendritic cell subsets emanating from monocytes in Th2-mediated inflammatory conditions respond differently to proinflammatory stimuli

The skin harbors two dendritic cell (DC) subsets, Langerhans cells (LC) and interstitial/dermal DC (IDDC), which traffic to lymph nodes after inflammation and ultraviolet stress. To demonstrate that monocytes may act as DC precursors for skin DC in postinflammatory recolonization, we generated LC an...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 80; no. 1; pp. 45 - 58
Main Authors:	Bechetoille, Nicolas, André, Valérie, Valladeau, Jenny, Perrier, Eric, Dezutter‐Dambuyant, Colette
Format:	Journal Article
Language:	English
Published:	United States Society for Leukocyte Biology 01-07-2006
Subjects:	Animals Cell Differentiation - immunology Cells, Cultured Cytokines - immunology Dendritic Cells - immunology differentiation Granulocyte Colony-Stimulating Factor - immunology Humans Inflammation - immunology Langerhans Cells - immunology Lipopolysaccharide Receptors - immunology Macrophage Colony-Stimulating Factor - immunology maturation Mice Monocytes - immunology Phenotype skin Th2 Cells - immunology Tissue Culture Techniques Transforming Growth Factor beta - immunology Tumor Necrosis Factor-alpha - immunology
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