Epitope Shaving Promotes Fungal Immune Evasion

The cell wall provides a major physical interface between fungal pathogens and their mammalian host. This extracellular armor is critical for fungal cell homeostasis and survival. Fungus-specific cell wall moieties, such as β-1,3-glucan, are recognized as pathogen-associated molecular patterns (PAMP...

Full description

Saved in:

Bibliographic Details
Published in:	mBio Vol. 11; no. 4
Main Authors:	Childers, Delma S, Avelar, Gabriela Mol, Bain, Judith M, Pradhan, Arnab, Larcombe, Daniel E, Netea, Mihai G, Erwig, Lars P, Gow, Neil A R, Brown, Alistair J P
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 07-07-2020
Subjects:	Anaerobiosis Animals Candida albicans Candida albicans - drug effects Candida albicans - enzymology Candida albicans - immunology castanospermine cell wall Cellulose 1,4-beta-Cellobiosidase - antagonists & inhibitors Cellulose 1,4-beta-Cellobiosidase - metabolism Epitopes - immunology Host-Microbe Biology Immune Evasion Lactic Acid - pharmacology Larva - microbiology Macrophages - microbiology Male Metabolic Networks and Pathways Mice Mice, Inbred C57BL Moths - microbiology Xog1 exoglucanase β-glucan shaving Candida albicans β-glucan shaving castanospermine immune evasion virulence Xog1 exoglucanase cell wall
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!