Coronary Artery Wall Shear Stress Is Associated With Progression and Transformation of Atherosclerotic Plaque and Arterial Remodeling in Patients With Coronary Artery Disease

Experimental studies suggest that low wall shear stress (WSS) promotes plaque development and high WSS is associated with plaque destabilization. We hypothesized that low-WSS segments in patients with coronary artery disease develop plaque progression and high-WSS segments develop necrotic core prog...

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Bibliographic Details
Published in:	Circulation (New York, N.Y.) Vol. 124; no. 7; pp. 779 - 788
Main Authors:	SAMADY, Habib, ESHTEHARDI, Parham, MCDANIEL, Michael C, JIN SUO, DHAWAN, Saurabh S, MAYNARD, Charles, TIMMINS, Lucas H, QUYYUMI, Arshed A, GIDDENS, Don P
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Lippincott Williams & Wilkins 16-08-2011
Subjects:	Aged Biological and medical sciences Blood and lymphatic vessels Calcinosis - diagnostic imaging Calcinosis - pathology Calcinosis - physiopathology Cardiology. Vascular system Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - pathology Coronary Artery Disease - physiopathology Coronary heart disease Coronary Vessels - diagnostic imaging Coronary Vessels - pathology Coronary Vessels - physiopathology Disease Progression Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Fibrosis Heart Humans Hydrodynamics Male Medical sciences Middle Aged Necrosis Plaque, Atherosclerotic - diagnostic imaging Plaque, Atherosclerotic - pathology Plaque, Atherosclerotic - physiopathology Prospective Studies Stress, Mechanical Ultrasonography, Interventional - methods Human coronary artery disease intravascular ultrasonography Coronary artery Cardiovascular disease Coronary heart disease interventional Vascular disease Atherosclerotic plaque Atherosclerosis Echography wall shear stress Shear stress Hemodynamics
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