Glenoid cartilage mechanical properties decrease after rotator cuff tears in a rat model

• Published in: Journal of orthopaedic research Vol. 30; no. 9; pp. 1435 - 1439
• Main Authors: Reuther, Katherine E., Sarver, Joseph J., Schultz, Susan M., Lee, Chang Soo, Sehgal, Chandra M., Glaser, David L., Soslowsky, Louis J.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01-09-2012
• Subjects: animal model; Animals; Cartilage, Articular - physiopathology; Disease Models, Animal; Elastic Modulus; glenohumeral arthritis; glenoid cartilage; Male; Rats; Rats, Sprague-Dawley; rotator cuff; Rotator Cuff Injuries; Tendon Injuries - physiopathology
• ISSN: 0736-0266; 1554-527X
• DOI: 10.1002/jor.22100

Rotator cuff repairs are commonly performed to reduce pain and restore function. Tears are also treated successfully without surgical intervention; however, the effect that a torn tendon has on the glenohumeral cartilage remains unknown. Clinically, a correlation between massive rotator cuff tears and glenohumeral arthritis has often been observed. This may be due to a disruption in the balance of forces at the shoulder, resulting in migration of the humeral head and subsequently, abnormal loading of the glenoid. Our lab previously demonstrated changes in ambulation and intact tendon mechanical properties following supraspinatus and infraspinatus rotator cuff tendon tears in a rat model. Therefore, the purpose of this study was to investigate the effects of supraspinatus and infraspinatus rotator cuff tears on the glenoid cartilage. Nine rats underwent unilateral detachment of the supraspinatus and infraspinatus tendons and were sacrificed after 4 weeks. Cartilage thickness significantly decreased in the antero‐inferior region of injured shoulders. In addition, equilibrium elastic modulus significantly decreased in the center, antero‐superior, antero‐inferior, and superior regions. These results suggest that altered loading after rotator cuff injury may lead to damage to the joint with significant pain and dysfunction. Clinically, understanding the mechanical processes involved with joint damage will allow physicians to better advise patients. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 30:1435–1439, 2012