Atherosclerotic lesion development in hypercholesterolemic Japanese quail following probucol treatment: a biochemical and morphologic evaluation

Probucol, a cholesterol-lowering agent which possesses antioxidant properties, was evaluated in hypercholesterolemic Japanese quail in order to assess the significance of antioxidant therapy on the development of atherosclerosis. Forty quail were fed a 0.5% cholesterol diet containing 0, 100, 200 or...

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Bibliographic Details
Published in:	Pharmacological research Vol. 29; no. 1; p. 65
Main Authors:	Bocan, T M, Mazur, M J, Mueller, S B, Charlton, G, Kieft, K A, Krause, B R
Format:	Journal Article
Language:	English
Published:	Netherlands 01-01-1994
Subjects:	Animals Aorta - pathology Arteriosclerosis - drug therapy Arteriosclerosis - etiology Arteriosclerosis - pathology Cholesterol - blood Cholesterol Esters - blood Cholesterol Esters - metabolism Cholesterol, Dietary - administration & dosage Coturnix - metabolism Diet, Atherogenic Histocytochemistry Hypercholesterolemia - blood Hypercholesterolemia - complications Hypercholesterolemia - metabolism Lipoproteins - blood Liver - metabolism Male Probucol - blood Probucol - therapeutic use
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