Expression of Nuclear Antigen Ki-67 in Prostate Cancer Needle Biopsy and Radical Prostatectomy Specimens

• Published in: JNCI : Journal of the National Cancer Institute Vol. 92; no. 23; pp. 1941 - 1942
• Main Authors: Mucci, Neil R., Rubin, Mark A., Strawderman, Myla S., Montie, James E., Smith, David C., Pienta, Kenneth J.
• Format: Journal Article
• Language: English
• Published: Cary, NC Oxford University Press 06-12-2000; Oxford Publishing Limited (England)
• Subjects: Biological and medical sciences; Biomarkers, Tumor - analysis; Biopsy; Biopsy, Needle; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen - analysis; Male; Medical sciences; Mitotic Index; Nephrology. Urinary tract diseases; Prostate cancer; Prostatectomy; Prostatic Neoplasms - immunology; Prostatic Neoplasms - pathology; Prostatic Neoplasms - surgery; Tumors of the urinary system; Urinary tract. Prostate gland; Adenocarcinoma; Human; Cell proliferation; Postoperative; Urinary system disease; Prostate disease; Biological marker; Malignant tumor; Pathology; Biopsy; Needle; Ki67 antigen; Preoperative; Male genital diseases; Prostate
• ISSN: 0027-8874; 1460-2105; 1460-2105
• DOI: 10.1093/jnci/92.23.1941

The histopathologic characteristics of the RP specimens are reported in Table 1 and are representative of the current types of prostate cancers seen at our institution. The biopsy samples of 45 patients were analyzed for expression of Ki-67 nuclear antigen. Thirty-eight of 45 patients had matching postsurgical biopsy and RP histology specimens available for comparative analysis. Sample dropout was due to inadequate staining of available material.