Antimicrobial photodynamic therapy alone or in combination with antibiotic local administration against biofilms of Fusobacterium nucleatum and Porphyromonas gingivalis

Antimicrobial photodynamic therapy (aPDT) kills several planktonic pathogens. However, the susceptibility of biofilm-derived anaerobic bacteria to aPDT is poorly characterized. Here, we evaluated the effect of Photodithazine (PDZ)-mediated aPDT on Fusobacterium nucleatum and Porphyromonas gingivalis...

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Bibliographic Details
Published in:	Journal of photochemistry and photobiology. B, Biology Vol. 188; pp. 135 - 145
Main Authors:	Tavares, Lívia J., de Avila, Erica D., Klein, Marlise I., Panariello, Beatriz H.D., Spolidório, Denise M.P., Pavarina, Ana Cláudia
Format:	Journal Article
Language:	English
Published:	Switzerland Elsevier B.V 01-11-2018 Elsevier BV
Subjects:	Anaerobic bacteria Anaerobic conditions Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antibiotics Antiinfectives and antibacterials Bacteria Biofilms Biofilms - drug effects Biofilms - radiation effects Combined modality therapy Fusobacterium nucleatum Fusobacterium nucleatum - isolation & purification Fusobacterium nucleatum - physiology Glucosamine - analogs & derivatives Glucosamine - chemistry Humans Light Light emitting diodes Metronidazole Metronidazole - pharmacology Microbial Sensitivity Tests Microbial Viability - drug effects Minimum inhibitory concentration Photodynamic therapy Photosensitizing Agents - chemistry Photosensitizing Agents - pharmacology Polystyrene Polystyrene resins Porphyromonas gingivalis Porphyromonas gingivalis - isolation & purification Porphyromonas gingivalis - physiology Reduction Saliva - microbiology Species Viability Anaerobic bacteria Photodynamic therapy Metronidazole Combined modality therapy
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