Assessment of hepatobiliary function in vivo and ex vivo in the rat

Many xenobiotics cause hepatobiliary toxicity and cholestasis in the rat. Initial assessment of hepatobiliary damage in rats can be accomplished by measuring serum concentrations of bile acids and bilirubin, serum activities of liver-associated enzymes such as 5'-nucleotidase, alkaline phosphat...

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Bibliographic Details
Published in:Journal of pharmacological and toxicological methods Vol. 31; no. 1; p. 11
Main Authors: Handler, J A, Kossor, D C, Goldstein, R S
Format: Journal Article
Language:English
Published: United States 01-02-1994
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