Effects of dietary tryptophan variations on extracellular serotonin in the dorsal hippocampus of rats

There is evidence to suggest that the efficacy of selective serotonin reuptake inhibitors (SSRIs) in depression is dependent on the availability of serotonin (5-HT) in the brain. Moreover, there is circumstantial evidence suggesting that plasma tryptophan (TRP) levels can predict response to SSRIs....

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Bibliographic Details
Published in:	Psychopharmacologia Vol. 172; no. 2; pp. 137 - 144
Main Authors:	VAN DER STELT, Hiske M, BROERSEN, Laus M, OLIVIER, Berend, WESTENBERG, Herman G. M
Format:	Journal Article
Language:	English
Published:	Berlin Springer 01-03-2004 Springer Nature B.V
Subjects:	Animals Biological and medical sciences Diet Dose-Response Relationship, Drug Experiments Extracellular Fluid - drug effects Extracellular Fluid - metabolism Fundamental and applied biological sciences. Psychology Hippocampus - drug effects Hippocampus - metabolism Hippocampus - secretion Laboratory animals Male Medical sciences Mental depression Neuropharmacology Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopharmacology Rats Rats, Sprague-Dawley Serotonin Serotonin - metabolism Serotonin - secretion Serotonin Uptake Inhibitors - pharmacology Tryptophan - administration & dosage Netherlands Rat Serotonin Psychotropic Rodentia Tryptophan Rats Hypnotic Extracellular DRL-72 s Vertebrata Mammalia Microdialysis Diet Aminoacid Animal Neurotransmitter Hippocampus Tryptophan Diet
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