Gastric Fluid Metabolomics Predicting the Need for Surfactant Replacement Therapy in Very Preterm Infants Results of a Case-Control Study

Respiratory distress syndrome (RDS) is a major morbidity of prematurity. In this case-control study, we prospectively evaluated whether untargeted metabolomic analysis (gas chromatography-mass spectrometry) of the gastric fluid could predict the need for surfactant in very preterm neonates. 43 infan...

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Bibliographic Details
Published in:	Metabolites Vol. 14; no. 4; p. 196
Main Authors:	Besiri, Konstantia, Begou, Olga, Lallas, Konstantinos, Kontou, Angeliki, Agakidou, Eleni, Deda, Olga, Gika, Helen, Verykouki, Eleni, Sarafidis, Kosmas
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01-04-2024
Subjects:	Apgar score Continuous positive airway pressure Drug therapy Gas chromatography gastric fluid GC-MS Gestational age Health aspects Hypertension Infants Infants (Premature) Intubation L-Serine Lung diseases Lung surfactant, Synthetic Mass spectroscopy Metabolites Metabolomics Metabonomic analysis Morbidity Neonates Newborn babies Pediatric research prediction Premature babies prematurity Prognosis Proline RDS Respiration Respiratory distress syndrome Steroids surfactant Surfactants Temperature Greece Germany GC-MS RDS gastric fluid prediction prematurity surfactant
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