Multiple-dose pharmacokinetics and excretion balance of gatifloxacin, a new fluoroquinolone antibiotic, following oral administration to healthy Caucasian volunteers

The multiple-dose pharmacokinetics and excretion balance of gatifloxacin were evaluated in 42 healthy Caucasian volunteers. Following multiple oral doses of 400 and 600 mg, the pharmacokinetics of gatifloxacin were similar on days 1 and 15, suggesting no therapeutically relevant time-dependent chang...

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Bibliographic Details

Published in:	Chemotherapy (Basel) Vol. 48; no. 3; p. 116
Main Authors:	Mignot, Alain, Guillaume, Michel, Brault, Muriel, Gualano, Virginie, Millérioux, Laurette, Göhler, Karin, Stahlberg, Hans-Jüergen
Format:	Journal Article
Language:	English
Published:	Switzerland 01-07-2002
Subjects:	Administration, Oral Adult Anti-Infective Agents - administration & dosage Anti-Infective Agents - pharmacokinetics Anti-Infective Agents - urine Drug Administration Schedule European Continental Ancestry Group Feces - chemistry Fluoroquinolones Half-Life Humans Male
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