Depressive symptoms associated with dabigatran: a case report

• Published in: Psychogeriatrics Vol. 15; no. 3; pp. 209 - 211
• Main Authors: Eryilmaz, Gul, Enez Darcin, Asli, Saglam, Esra, Gogcegoz Gul, Isil
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01-09-2015
• Subjects: antidepressants; Antithrombins - adverse effects; Antithrombins - therapeutic use; Atrial Fibrillation - drug therapy; Cardiac arrhythmia; Citalopram - therapeutic use; dabigatran; Dabigatran - adverse effects; Dabigatran - therapeutic use; depression; Depression - chemically induced; Depression - drug therapy; drug interaction; Drug Interactions; Humans; Male; Physicians; Sleep Wake Disorders - etiology; Sleep Wake Disorders - psychology; Social Isolation - psychology; Treatment Outcome; dabigatran; antidepressants; depression; drug interaction
• ISSN: 1346-3500; 1479-8301
• DOI: 10.1111/psyg.12099

Several studies have reported that depression and anxiety are very common in atrial fibrillation due to impaired quality of life. Dabigatran is an anti‐aggregation agent used for the treatment of atrial fibrillation. In terms of drug interactions during treatment with dabigatran, patients suffering from minor depression are reported to be a population at risk. This report is about a 68‐year‐old man whose depressive symptoms were aggravated after taking dabigatran for atrial fibrillation. The case is discussed in terms of his aggravated depressive symptoms and the interaction between his prescription medications.