Werner's Syndrome Associated with Cholangiocarcinoma

A 38-year-old Japanese man had cholangiocarcinoma in association with typical features of Werner's syndrome. Thereplicative capacity of fibroblasts in culture was characteristically reduced, and the in vitro natural killer cell activity was deficient. He died of massive G-I tract bleeding 8 mon...

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Bibliographic Details
Published in:	Japanese Journal of Medicine Vol. 25; no. 2; pp. 179 - 183
Main Authors:	OKAMURA, Hideki, YANAGI, Yusuke, IMARI, Yasuhisa, KUDO, Jiro, ISHIBASHI, Hiromi, USHIJIMA, Masahiro, IMAMURA, Takashi
Format:	Journal Article
Language:	English
Published:	Japan The Japanese Society of Internal Medicine 1986
Subjects:	Adenoma, Bile Duct - etiology Adult Aging Bile Duct Neoplasms - etiology Cells, Cultured Cholangiocarcinoma Fibroblasts - metabolism Humans Killer Cells, Natural - immunology Male Mutation Natural killer cells Premature aging Werner Syndrome - complications Werner Syndrome - genetics Werner's syndrome
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Summary:	A 38-year-old Japanese man had cholangiocarcinoma in association with typical features of Werner's syndrome. Thereplicative capacity of fibroblasts in culture was characteristically reduced, and the in vitro natural killer cell activity was deficient. He died of massive G-I tract bleeding 8 months after admission.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0021-5120 1881-123X
DOI:	10.2169/internalmedicine1962.25.179