Concise Asymmetric Syntheses of Streptazone A and Abikoviromycin

Streptazone A and abikoviromycin are alkaloids that both feature an unusual arrangement of reactive functionalities within a compact tricyclic ring system. Here, we report a highly concise asymmetric synthesis of both natural products. The route first constructs another family member, streptazone B1...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 60; no. 19; pp. 10521 - 10525
Main Authors:	Wørmer, Gustav J., Villadsen, Nikolaj L., Nørby, Peter, Poulsen, Thomas B.
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 03-05-2021
Edition:	International ed. in English
Subjects:	asymmetric catalysis Asymmetric synthesis Asymmetry Conjugation electrophile Enantiomers Epoxidation Iridium Natural products Rhodium Target recognition total synthesis transition metal catalysis electrophile natural products asymmetric catalysis total synthesis transition metal catalysis
Online Access:	Get full text
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