Use of the Quorum-Sensing Inhibitor RNAIII-Inhibiting Peptide to Prevent Biofilm Formation In Vivo by Drug-Resistant Staphylococcus epidermidis

Staphylococcus epidermidis is a frequent cause of infections associated with foreign bodies and indwelling medical devices. The bacteria are capable of surviving antibiotic treatment through encapsulation into biofilms. RNAIII-inhibiting peptide (RIP) is a heptapeptide that inhibits S. aureus pathog...

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Bibliographic Details
Published in:	The Journal of infectious diseases Vol. 187; no. 4; pp. 625 - 630
Main Authors:	Balaban, Naomi, Giacometti, Andrea, Cirioni, Oscar, Gov, Yael, Ghiselli, Roberto, Mocchegiani, Federico, Viticchi, Claudio, Del Prete, Maria Simona, Saba, Vittorio, Scalise, Giorgio, Dell’Acqua, Giorgio
Format:	Journal Article
Language:	English
Published:	Chicago, IL The University of Chicago Press 15-02-2003 University of Chicago Press Oxford University Press
Subjects:	Animal traps Animals Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria Bacterial Adhesion Bacterial Proteins Biofilms Biofilms - growth & development Biological and medical sciences Cell Line Drug Resistance Humans Infections Male Medical sciences Oligopeptides - pharmacology Pharmacology. Drug treatments Phosphoproteins - metabolism Phosphorylation - drug effects Rats Staphylococcal Infections - drug therapy Staphylococcus Staphylococcus aureus Staphylococcus epidermidis Staphylococcus epidermidis - drug effects Staphylococcus epidermidis - metabolism Tissue grafting Peptides Infection Prevention Resistance In vivo Antibiotic Staphylococcus epidermidis Bacteriosis Biofilm Bacteria Micrococcales Micrococcaceae Medical device Inhibitor Quorum sensing Antibacterial agent Staphylococcal infection
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