COVID-19 Inflammatory Syndrome: Lessons from TNFRI and CRP about the Risk of Death in Severe Disease

: Cytokine storm in severe COVID-19 is responsible for irreversible tissue damage and death. Soluble mediators from the TNF superfamily, their correlation with clinical outcome, and the use of TNF receptors as a potent predictor for clinical outcome were evaluated. : Severe COVID-19 patients had the...

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Bibliographic Details
Published in:	Biomedicines Vol. 12; no. 9; p. 2138
Main Authors:	Farnesi-de-Assunção, Thaís Soares, Oliveira-Scussel, Ana Carolina de Morais, Rodrigues, Wellington Francisco, Matos, Beatriz Sodré, da Silva, Djalma Alexandre Alves, de Andrade E Silva, Leonardo Eurípedes, Mundim, Fabiano Vilela, Helmo, Fernanda Rodrigues, Bernardes E Borges, Anna Victória, Desidério, Chamberttan Souza, Trevisan, Rafael Obata, Obata, Malu Mateus Santos, Barbosa, Laís Milagres, Lemes, Marcela Rezende, Costa-Madeira, Juliana Cristina, Barbosa, Rafaela Miranda, Cunha, Andrezza Cristina Cancian Hortolani, Pereira, Loren Queli, Tanaka, Sarah Cristina Sato Vaz, de Vito, Fernanda Bernadelli, Monteiro, Ivan Borges, Ferreira, Yulsef Moura, Machado, Guilherme Henrique, Moraes-Souza, Hélio, Rodrigues, Denise Bertulucci Rocha, de Oliveira, Carlo José Freire, da Silva, Marcos Vinicius, Júnior, Virmondes Rodrigues
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 20-09-2024 MDPI
Subjects:	Brazil clinical outcomes predictor Consent COVID-19 Cytokine storm Death Disease Diseases Erythrocytes Hematocrit Hemoglobin Hospitalization Infections inflammatory mediators Interleukins Leptin Leukocytes (neutrophilic) Lymphocytes Monocytes Regression analysis SARS-CoV-2 Serum levels Severe acute respiratory syndrome coronavirus 2 Software Statistical models TNF receptors TNF superfamily Tumor necrosis factor receptors γ-Interferon Brazil United States > US COVID-19 inflammatory mediators SARS-CoV-2 C-reactive protein TNF superfamily clinical outcomes predictor TNF receptors
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