Colonic Schwannoma: A Case Study and Literature Review of a Rare Entity and Diagnostic Dilemma

An asymptomatic 73-year-old woman was found to have a submucosal mass in the descending colon on routine colonoscopy. A CT scan revealed a 31 × 28 × 31 mm lesion in the same location. Previous biopsy proved to be nondiagnostic, and the patient underwent a laparoscopic descending colon resection. His...

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Bibliographic Details
Published in:The American surgeon Vol. 82; no. 12; p. 1183
Main Authors: Uhr, Alex, Singh, Awinder P, Munoz, Jose, Aka, Allison, Sion, Melanie, Jiang, Wei, Goldstein, Scott D, Rosato, Ernest L
Format: Journal Article
Language:English
Published: United States 01-12-2016
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Summary:An asymptomatic 73-year-old woman was found to have a submucosal mass in the descending colon on routine colonoscopy. A CT scan revealed a 31 × 28 × 31 mm lesion in the same location. Previous biopsy proved to be nondiagnostic, and the patient underwent a laparoscopic descending colon resection. Histologic evaluation of the tumor revealed a low grade spindle cell neoplasm with strong, diffuse positivity for S-100 protein by immunohistochemistry, leading to the diagnosis of schwannoma. A review of the literature revealed intestinal schwannoma to be a rare disease entity, with only about 50 cases previously reported.
ISSN:1555-9823
DOI:10.1177/000313481608201224