Workflow for comparison of chemical and biological metrics of filter collected PM2.5

• Published in: Atmospheric environment (1994) Vol. 226; p. 117379
• Main Authors: Roper, Courtney, Perez, Allison, Barrett, Damien, Hystad, Perry, Massey Simonich, Staci L., Tanguay, Robyn L.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-04-2020
• Subjects: Household air pollution; Indoor PM2.5; Oxidative potential; PAH diagnostic ratios; PM2.5 composition; Zebrafish; PM2.5 composition; Zebrafish; Oxidative potential; PAH diagnostic ratios; Household air pollution; Indoor PM2.5
• ISSN: 1352-2310; 1873-2844
• DOI: 10.1016/j.atmosenv.2020.117379

There is limited understanding of adverse health effect associations with chemical constituents of fine particulate matter (PM2.5) as well as the underlying mechanisms. We outlined a workflow to assess metrics, beyond concentration, using household and personal PM2.5 filter samples collected in India as a proof of concept for future large-scale studies. Oxidative potential, chemical composition (polycyclic aromatic hydrocarbons and elements), and bioactivity (developmental exposures in zebrafish) were determined. Significant differences were observed in all metrics between personal and household PM2.5 samples. This work established methods to characterize multiple metrics of PM2.5 to ultimately support the identification of more health-relevant metrics than concentration.
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•PM2.5 concentrations are frequently used for regulatory guidelines.•More health-relevant metrics for PM2.5 exposures must be explored.•Workflow for robust characterization of PM2.5 was developed.•Differences between personal and stationary PM2.5 monitors.