Ablation of sensory nerves favours melanoma progression

The tumour mass is composed not only of heterogeneous neoplastic cells, but also a variety of other components that may affect cancer cells behaviour. The lack of detailed knowledge about all the constituents of the tumour microenvironment restricts the design of effective treatments. Nerves have be...

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Bibliographic Details
Published in:	Journal of cellular and molecular medicine Vol. 24; no. 17; pp. 9574 - 9589
Main Authors:	Prazeres, Pedro H. D. M., Leonel, Caroline, Silva, Walison N., Rocha, Beatriz G. S., Santos, Gabryella S. P., Costa, Alinne C., Picoli, Caroline C., Sena, Isadora F. G., Gonçalves, William A., Vieira, Mariana S., Costa, Pedro A. C., Campos, Leda M. C. C., Lopes, Miriam T. P., Costa, Marcos R., Resende, Rodrigo R., Cunha, Thiago M., Mintz, Akiva, Birbrair, Alexander
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01-09-2020 John Wiley and Sons Inc
Subjects:	Ablation Animals Cancer Cell Communication - physiology Cell culture Cell Line, Tumor Confocal microscopy Denervation Disease Progression Experiments genetic depletion Humans Melanoma Melanoma - pathology Mice Mice, Inbred C57BL Nervous system Original Retrospective Studies sensory nerves Sensory neurons Sensory Receptor Cells - pathology Skin Neoplasms - pathology Tumor Microenvironment Tumors tumour microenvironment Fiji genetic depletion melanoma tumour microenvironment sensory nerves
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