Variability of Outer Membrane Protein P1 and Its Evaluation as a Vaccine Candidate against Experimental Otitis Media due to Nontypeable Haemophilus influenzae: an Unambiguous, Multifaceted Approach

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Published in:	Infection and Immunity Vol. 68; no. 8; pp. 4505 - 4517
Main Authors:	BOLDUC, G. R, BOUCHET, V, JIANG, R.-Z, GEISSELSODER, J, TRUONG-BOLDUC, Q. C, RICE, P. A, PELTON, S. I, GOLDSTEIN, R
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-08-2000
Subjects:	Amino Acid Sequence Animals Antigenic Variation AP1 protein Bacterial Outer Membrane Proteins - genetics Bacterial Outer Membrane Proteins - therapeutic use Bacteriology Biological and medical sciences Chinchilla Drug Design Ear, Middle - microbiology Fundamental and applied biological sciences. Psychology Haemophilus influenzae Haemophilus influenzae - classification Haemophilus Vaccines - therapeutic use Microbial Immunity and Vaccines Microbiology Molecular Sequence Data Mutagenesis, Insertional Otitis Media - prevention & control Recombinant Proteins - immunology Sequence Homology, Amino Acid Transformation, Bacterial Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Membrane protein Genetic variability Middle ear disease Vaccine External membrane Haemophilus influenzae Infection Pasteurellaceae Experimental disease Gene Bacteriosis Bacteria ENT disease Otitis media
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Summary:	Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue IAI About IAI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy Connect to IAI IAI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0019-9567 Online ISSN: 1098-5522 Copyright © 2014 by the American Society for Microbiology. For an alternate route to IAI .asm.org, visit: IAI
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 Present address: Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071, People's Republic of China. Corresponding author. Mailing address: Section of Molecular Genetics, Division of Pediatric Infectious Diseases, Maxwell Finland Laboratory for Infectious Diseases, Boston University School of Medicine, 774 Albany St., Boston, MA 02118. Phone: (617) 638-5328. Fax: (617) 414-7222. E-mail: genetics@bu.edu. Present address: Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
ISSN:	0019-9567 1098-5522
DOI:	10.1128/IAI.68.8.4505-4517.2000