Dual natural infection with bovine viral diarrhea virus -1 and -2 in a stillborn calf: tissue distribution and molecular characterization

• Published in: Open veterinary journal (Tripoli, Libya) Vol. 8; no. 4; pp. 493 - 497
• Main Authors: Spetter, Maximiliano J., Uriarte, Enrique L. Louge, Altamiranda, Erika A. González, Leunda, María R., Pereyra, Susana B., Verna, Andrea E., Odeón, Anselmo C.
• Format: Journal Article
• Language: English
• Published: Tripoli, Libya Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology 01-01-2018; Tripoli University
• Subjects: Bovine viral diarrhea virus; Co-infection; Phylogenetic analysis; Short Communication
• ISSN: 2226-4485; 2218-6050; 2218-6050
• DOI: 10.4314/ovj.v8i4.23

Dual infections with both bovine viral diarrhea virus (BVDV)-1 and -2 seem to be unusual. The aim of this study was to describe an infection with both BVDV genotypes in a stillborn calf. Virus isolation and phylogenetic analyses of the 5´UTR and NS5B regions confirmed the presence of BVDV-1b and -2b in spleen and lung, whereas BVDV-2b was also detected in brain, heart, liver, kidney and, fluid of cavities. These results confirm that dual infections with both BVDV-1 and BVDV-2 species can occur naturally and their tissue distribution can be different.