Livedoid vasculopathy associated with peripheral neuropathy: a report of two cases

• Published in: Anais brasileiros de dermatología Vol. 88; no. 6 Suppl 1; pp. 227 - 229
• Main Authors: Tubone, Mariana Quirino, Escobar, Gabriela Fortes, Peruzzo, Juliano, Schestatsky, Pedro, Maldonado, Gabriela
• Format: Journal Article
• Language: English
• Published: Spain Sociedade Brasileira de Dermatologia 01-12-2013
• Subjects: Biopsy; Case Report; DERMATOLOGY; Diagnosis, Differential; Female; Humans; Livedo reticularis; Livedo Reticularis - complications; Livedo Reticularis - pathology; Middle Aged; Mononeuropathies; Peripheral Nervous System Diseases - complications; Peripheral Nervous System Diseases - pathology; Polyneuropathies; Skin diseases, vascular; Skin Ulcer - pathology; Skin diseases, vascular; Livedo reticular; Mononeuropathies; Polyneuropathies; Mononeuropatias; Livedo reticularis; Dermatopatias vasculares; Polineuropatias
• ISSN: 0365-0596; 1806-4841; 1806-4841; 0365-0596
• DOI: 10.1590/abd1806-4841.20132363

Livedoid vasculopathy (LV) is a chronic and recurrent disease consisting of livedo reticularis and symmetric ulcerations, primarily located on the lower extremities, which heal slowly and leave an atrophic white scar ("atrophie blanche"). Neurological involvment is rare and presumed to be secondary to the ischemia from vascular thrombosis of the vasa nervorum. Laboratory evaluation is needed to exclude secondary causes such as hyper-coagulable states, autoimmune disorders and neoplasms. We present two patients with a rare association of peripheral neuropathy and LV, thereby highlighting the importance of a multidisciplinary approach to reach the correct diagnosis.