The regulation of the homeostasis and regeneration of peripheral nerve is distinct from the CNS and independent of a stem cell population

Peripheral nerves are highly regenerative, in contrast to the poor regenerative capabilities of the central nervous system (CNS). Here, we show that adult peripheral nerve is a more quiescent tissue than the CNS, yet all cell types within a peripheral nerve proliferate efficiently following injury....

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Bibliographic Details
Published in:	Development (Cambridge) Vol. 145; no. 24
Main Authors:	Stierli, Salome, Napoli, Ilaria, White, Ian J, Cattin, Anne-Laure, Monteza Cabrejos, Anthony, Garcia Calavia, Noelia, Malong, Liza, Ribeiro, Sara, Nihouarn, Julie, Williams, Richard, Young, Kaylene M, Richardson, William D, Lloyd, Alison C
Format:	Journal Article
Language:	English
Published:	England The Company of Biologists Ltd 14-12-2018
Subjects:	Animals Axons - metabolism Carcinogenesis - pathology Cell Proliferation Central Nervous System - physiology Extracellular Matrix Proteins - metabolism Homeostasis Mice, Inbred C57BL Mice, Transgenic Myelin Sheath - metabolism Nerve Regeneration - physiology Neural Stem Cells - cytology Neural Stem Cells - metabolism Neuronal Plasticity Peripheral Nerves - cytology Peripheral Nerves - physiology Peripheral Nerves - ultrastructure Schwann Cells - metabolism Stem Cells and Regeneration CNS Tissue homeostasis PNS Tissue regeneration Schwann cells Stem cells
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