The Effect of Socioeconomic Factors on Quality of Life After Treatment in Patients With Head and Neck Cancer

• Published in: International journal of radiation oncology, biology, physics Vol. 70; no. 1; pp. 23 - 27
• Main Authors: Demiral, Ayşe Nur, M.D, Şen, Mehmet, M.D, Demiral, Yücel, M.D, Knay, Münir, M.D
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2008
• Subjects: Adult; Aged; CARCINOMAS; Educational Status; Female; HEAD; Head and neck cancer; Head and Neck Neoplasms - drug therapy; Head and Neck Neoplasms - radiotherapy; Head and Neck Neoplasms - surgery; Hematology, Oncology and Palliative Medicine; Humans; Male; Middle Aged; NECK; PATIENTS; Quality of Life; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; RADIOTHERAPY; Radiotherapy Dosage; REGRESSION ANALYSIS; SF-36; Social Security; Socioeconomic Factors; Socioeconomic status; Statistics, Nonparametric; SURGERY; Surveys and Questionnaires; Head and neck cancer; Socioeconomic status; Radiotherapy; Quality of life; SF-36
• ISSN: 0360-3016; 1879-355X
• DOI: 10.1016/j.ijrobp.2007.05.056

Purpose To determine the effect of socioeconomic factors on quality of life (QoL) after treatment in patients with head and neck carcinoma (HNC). Patients and Methods The study population included 50 HNC patients seen in their control examinations after radiotherapy during a 2-month interval and who were willing to complete the Short-Form 36 QoL questionnaire. Socioeconomic, demographic, and tumor- and treatment-related factors were analyzed for their effect on physical component summary score (PCS) and mental component summary score (MCS) using the Mann-Whitney U test. Results All patients received radiotherapy, and 33 patients (66%) underwent surgery for the primary tumor and/or neck disease. Chemotherapy was given in 9 patients (18%). Mean PCS and MCS were 47.9 (range, 24.8–59.3) and 46.7 (range, 22–63.3) for the whole patient population. There was no significant factor affecting PCS. Education level of “middle school or higher,” perceived economic status of “medium or higher,” social security status of not being “absent or minimally covered,” and unilateral type of neck surgery were found to increase MCS significantly. According to separate linear regression analyses performed for three socioeconomic variables, the most significant factor for MCS was social security status compared with education level and perceived economic status. It was the only parameter that retained its significance when all five parameters were combined in a linear regression model. Conclusion This study demonstrated that educational status, perceived economic status, and social security status showed a significant effect on the QoL of HNC patients after radiotherapy. When all variables were taken into account, only “social security status” remained significant.