Repeated cocaine or methamphetamine treatment alters astrocytic CRF2 and GLAST expression in the ventral midbrain

Dopamine neurons in the substantia nigra (SN) and ventral tegmental area (VTA) play a central role in the reinforcing properties of abused drugs including methamphetamine and cocaine. Chronic effects of psychostimulants in the SN/VTA also involve non‐dopaminergic transmitters, including glutamate an...

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Bibliographic Details
Published in:	Addiction biology Vol. 27; no. 2; pp. e13120 - n/a
Main Authors:	Sharpe, Amanda L., Trzeciak, Marta, Eliason, Nicole L., Blankenship, Harris E., Byrd, Bre' Ana M., Douglas, Phillip D., Freeman, Willard M., Beckstead, Michael J.
Format:	Journal Article
Language:	English
Published:	United States John Wiley & Sons, Inc 01-03-2022
Subjects:	Amino Acid Transport System X-AG - metabolism Animals Astrocytes Astrocytes - metabolism Chronic effects Cocaine Cocaine - pharmacology Corticotropin-Releasing Hormone - metabolism Dopamine Dopamine receptors Drug abuse Hybridization Hydroxylase Immunofluorescence Labeling Localization Mesencephalon Methamphetamine Methamphetamine - pharmacology Mice Neurotransmission Neurotransmitter receptors NuTRAP psychostimulant S100β Substantia nigra Transcription Tyrosine 3-monooxygenase ventral tegmental area Ventral Tegmental Area - drug effects Ventral Tegmental Area - metabolism Ventral tegmentum substantia nigra ventral tegmental area S100β mice NuTRAP psychostimulant
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