The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation

The complement system plays an important role in host defense and is activated via three different activation pathways. We have previously reported that mannose-binding lectin-associated serine protease (MASP)-3, unlike its splicing variant MASP-1, circulates in an active form and is essential for t...

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Bibliographic Details

Published in:	Frontiers in immunology Vol. 13; p. 907023
Main Authors:	Kusakari, Kohei, Machida, Takeshi, Ishida, Yumi, Omori, Tomoko, Suzuki, Toshiyuki, Sekimata, Masayuki, Wada, Ikuo, Fujita, Teizo, Sekine, Hideharu
Format:	Journal Article
Language:	English
Published:	Frontiers Media S.A 16-08-2022
Subjects:	alternative pathway complement Immunology lectin pathway MASP-3 pattern recognition molecules
Online Access:	Get full text
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