Protective effect of ω-3 polyunsaturated fatty acids (PUFAs) on sodium nitroprusside-induced nephrotoxicity and oxidative damage in rat kidney

Sodium nitroprusside (SNP) a nitric oxide (NO) donor has proven toxic effects. Dietary ω-3 polyunsaturated fatty acid (PUFA) has been shown to reduce the severity of numerous ailments. Present study examined whether intake of fish oil (FO)/flaxseed oil (FXO, Omega Nutrition, St Vancouver, Canada) wo...

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Bibliographic Details
Published in:	Human & experimental toxicology Vol. 31; no. 10; p. 1035
Main Authors:	Khan, M W, Priyamvada, S, Khan, S A, Khan, S, Naqshbandi, A, Yusufi, A N K
Format:	Journal Article
Language:	English
Published:	England 01-10-2012
Subjects:	Animals Antioxidants - metabolism Biomarkers - blood Biomarkers - urine Blood Urea Nitrogen Carbohydrate Metabolism - drug effects Creatinine - blood Creatinine - urine Cytoprotection Dietary Supplements Disease Models, Animal Enzymes - blood Fatty Acids, Omega-3 - pharmacology Fish Oils - pharmacology Kidney - drug effects Kidney - metabolism Kidney - pathology Kidney Diseases - chemically induced Kidney Diseases - metabolism Kidney Diseases - pathology Kidney Diseases - prevention & control Linseed Oil - pharmacology Lipid Peroxidation - drug effects Lysosomes - drug effects Lysosomes - metabolism Male Microvilli - drug effects Microvilli - metabolism Nitric Oxide - metabolism Nitroprusside Oxidative Stress - drug effects Phosphates - metabolism Rats Rats, Wistar Time Factors
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