The therapeutic effect of continuous intracisternal L-Arginine infusion on experimental cerebral vasospasm

Recent studies on the pathogenesis of cerebral vasospasm following subarachnoid haemorrhage (SAH) suggest a breakdown of the balance between the vasoconstrictor and vasodilator systems. A shortage of a major cerebral vasodilator, nitric oxide (NO), has been accused of causing this breakdown. We inve...

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Bibliographic Details
Published in:	Acta neurochirurgica Vol. 143; no. 3; pp. 277 - 285
Main Authors:	Göksel, H M, Ozüm, U, Oztoprak, I
Format:	Journal Article
Language:	English
Published:	Wien Springer 01-01-2001 New York, NY Springer Nature B.V
Subjects:	Aneurysms Animals Arginine - pharmacology Biological and medical sciences Blood Flow Velocity - drug effects Catheters, Indwelling Cisterna Magna - drug effects Female Male Medical sciences Neurology Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase - physiology Pathogenesis Rabbits Subarachnoid Hemorrhage - diagnostic imaging Tropical medicine Ultrasonography, Doppler, Transcranial Up-Regulation - drug effects Vascular diseases and vascular malformations of the nervous system Vasoconstriction - drug effects Vasospasm, Intracranial - diagnostic imaging Nervous system diseases Pathogenesis Intracisternal administration Rabbit Cardiovascular disease Lagomorpha Hemorrhage Cerebral disorder Vascular disease Vertebrata Mammalia Arginine Animal Nitric oxide Central nervous system disease Subarachnoid L stereoisomer Complication Vasospasm Biological effect Cerebrovascular disease
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