Pharmacological studies of effort-related decision making using mouse touchscreen procedures: effects of dopamine antagonism do not resemble reinforcer devaluation by removal of food restriction

Rationale Effort-based decision-making tasks offer animals choices between preferred reinforcers that require high effort to obtain vs. low effort/low reward options. The neural mechanisms of effort-based choice are widely studied in rats, and evidence indicates that mesolimbic dopamine (DA) and rel...

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Bibliographic Details
Published in:	Psychopharmacology Vol. 237; no. 1; pp. 33 - 43
Main Authors:	Yang, Jen-Hau, Presby, Rose E., Jarvie, Adam A., Rotolo, Renee A., Fitch, R. Holly, Correa, Mercè, Salamone, John D.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 2020 Springer Springer Nature B.V
Subjects:	Analysis Animals Biomedical and Life Sciences Biomedicine Carbohydrates Choice Behavior - drug effects Decision making Decision Making - drug effects Dopamine Dopamine - pharmacology Dopamine Antagonists - pharmacology Dopamine D2 receptors Feeding Behavior - drug effects Food Food availability Food intake Food preferences Haloperidol Haloperidol - pharmacology Interactive computer systems Male Mesolimbic system Mice Motivation Neurosciences Operant conditioning Original Investigation Pellets Pharmacology/Toxicology Phenols Psychiatry Reinforcement Strawberries Panel pressing Schizophrenia Dopamine Motivation Preference test Bussey-Saksida chambers
Online Access:	Get full text
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