hoxa1a -Null Zebrafish as a Model for Studying HOXA1 -Associated Heart Malformation in Bosley-Salih-Alorainy Syndrome

Mutations in can lead to diseases such as Bosley-Salih-Alorainy syndrome, involving severe cardiovascular malformations. However, the role of in cardiac morphogenesis remains unclear. is a homologous gene to human in zebrafish. We used CRISPR to make -null zebrafish that exhibited multiple heart mal...

Full description

Saved in:

Bibliographic Details
Published in:	Biology (Basel, Switzerland) Vol. 12; no. 7; p. 899
Main Authors:	Wang, Hongjie, He, Jingwei, Han, Xuemei, Wu, Xiuzhi, Ye, Xuebin, Lv, Wenchao, Zu, Yao
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 23-06-2023 MDPI
Subjects:	Bosley–Salih–Alorainy syndrome Cardiovascular diseases Cartilage Cell adhesion & migration Congenital defects Coronary artery disease CRISPR Danio rerio EKG Embryos Ethanol Genes Genomes Heart Heart diseases heart malformation HOX gene HOXA1 protein hoxa1a Hybridization Morphogenesis Morphology Mutation Myocardium Photography Physiology Ventricle Vertebrates Zebrafish United States > US CRISPR zebrafish hoxa1a Bosley–Salih–Alorainy syndrome heart malformation
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!