A Critical Threshold of Meningococcal Factor H Binding Protein Expression Is Required for Increased Breadth of Protective Antibodies Elicited by Native Outer Membrane Vesicle Vaccines

• Published in: Clinical and Vaccine Immunology Vol. 18; no. 5; pp. 736 - 742
• Main Authors: Koeberling, Oliver, Delany, Isabel, Granoff, Dan M
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01-05-2011
• Subjects: Animals; Antibodies, Bacterial - blood; Antigens, Bacterial - immunology; Antigens, Bacterial - metabolism; Bacterial Proteins - immunology; Bacterial Proteins - metabolism; Blood Bactericidal Activity; Female; Gene Expression; Immunoglobulin G - blood; Meningococcal Vaccines - administration & dosage; Meningococcal Vaccines - genetics; Meningococcal Vaccines - immunology; Mice; Microbial Viability; Neisseria meningitidis; Neisseria meningitidis - immunology; Neisseria meningitidis - metabolism; Secretory Vesicles - immunology; Secretory Vesicles - metabolism; Vaccine Research
• ISSN: 1556-6811; 1556-679X; 1556-679X
• DOI: 10.1128/CVI.00542-10

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