Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery

Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery

In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule...

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Bibliographic Details
Published in:Theranostics Vol. 3; no. 12; pp. 986 - 1003
Main Authors: Yen, Swee Kuan, Padmanabhan, Parasuraman, Selvan, Subramanian Tamil
Format: Journal Article
Language:English
Published: Australia Ivyspring International Publisher 01-01-2013
Subjects:
Drug Carriers
Ferric Compounds - therapeutic use
Humans
Macromolecular Substances - therapeutic use
Nanoparticles - therapeutic use
Review
gold
iron oxide
miRNA delivery
nanoparticles
MRI
contrast agents
optical imaging
theranostics
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Summary:In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule delivery such as micro ribonucleic acid (microRNA). This review intends to highlight the recent advances in the synthesis and application of multifunctional NPs (mainly iron oxide) in theranostics, an area used to combine therapeutics and diagnostics. The recent applications of NPs in miRNA delivery are also reviewed.
Bibliography:Competing Interests: The authors have declared that no competing interest exists.
ISSN:1838-7640
1838-7640
DOI:10.7150/thno.4827