Giant Condyloma Acuminatum

• Published in: Dermatologic surgery Vol. 29; no. 3; pp. 300 - 303
• Main Authors: Ergün, Selma Sönmez, Kural, Yasemin Balsever, Büyükbabani, Nesimi, Verim, Levent, Akbulut, Habib, Gürkan, Levent
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Inc 01-03-2003; by the American Society for Dermatologic Surgery, Inc; Blackwell
• Subjects: Biological and medical sciences; Condylomata Acuminata - pathology; Condylomata Acuminata - surgery; Genital Diseases, Male - pathology; Genital Diseases, Male - surgery; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Middle Aged; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the genital tract and mammary gland; Viral diseases; Viral diseases of the genital and urinary system; Human; Giant condyloma acuminatum of Buschke Lowenstein; Male; Genital diseases; Infection; Case study; Chemotherapy; Sexually transmitted disease; Radical resection; Treatment; Surgery; Viral disease; Adult; Diagnosis
• ISSN: 1076-0512; 1524-4725
• DOI: 10.1046/j.1524-4725.2003.29067.x

BACKGROUND Giant condyloma acuminatum is a warty lesion that is characterized by its large size and propensity to infiltrate into deeper tissues contrasting with its microscopically benign pattern. It is proposed that giant condyloma represents an intermediate lesion between condyloma acuminatum and verrucous carcinoma.
OBJECTIVE A primary therapeutic option of giant condyloma is radical surgery with or without adjunctive chemotherapy. Because of the tumor's large extent in this case, curative therapy would have been achieved by wide surgical excision.
METHOD We present a morphologically and histologically classic example of giant condyloma with respect to origin from common genital warts. The reason for extensive exophytic growth was due to delay in therapy because of the patient's self neglect but not due to immune deficiency. The patient was treated with wide surgical excision.
RESULTS The postoperative period was uneventful, allowing satisfactory functional and cosmetic results.
CONCLUSION This case is an interesting case because of its exceptionally huge size without any deep tissue involvement and tissue atypia. This suggests that giant condyloma is an intermediate condition that exhibits a continuous tendency for growth.