Effect of Trigonella foenum-graecum and Ammi majus on calcium oxalate urolithiasis in rats

The present study was undertaken to investigate the effect of Trigonella foenum-graecum seed and Ammi majus fruit on experimentally-induced kidney stones. Oxalate urolithiasis in male rats was produced by the addition of 3% glycolic acid to their diet. After 4 weeks, highly significant deposition in...

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Bibliographic Details
Published in:	Journal of ethnopharmacology Vol. 26; no. 3; p. 249
Main Authors:	Ahsan, S K, Tariq, M, Ageel, A M, al-Yahya, M A, Shah, A H
Format:	Journal Article
Language:	English
Published:	Ireland 01-10-1989
Subjects:	Animals Calcium Oxalate - analysis Glycolates Male Medicine, Traditional Plants, Medicinal Rats Rats, Inbred Strains Urinary Calculi - analysis Urinary Calculi - chemically induced Urinary Calculi - prevention & control
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Summary:	The present study was undertaken to investigate the effect of Trigonella foenum-graecum seed and Ammi majus fruit on experimentally-induced kidney stones. Oxalate urolithiasis in male rats was produced by the addition of 3% glycolic acid to their diet. After 4 weeks, highly significant deposition in the kidneys was noticed and changes in water intake and body weight recorded. Daily oral treatment with T. foenum-graecum significantly decreased the quantity of calcium oxalate deposited in the kidneys thus supporting its use in Saudi folk medicine. The effects obtained by A. majus were, however, not significant.
ISSN:	0378-8741
DOI:	10.1016/0378-8741(89)90097-4