Identifying women with increased risk of breast cancer and implementing risk-reducing strategies and supplemental imaging
Breast cancer (BC) is the second most common cancer in women, affecting 1 in 8 women in the United States (12.5%) in their lifetime. However, some women have a higher lifetime risk of BC because of genetic and lifestyle factors, mammographic breast density, and reproductive and hormonal factors. Bec...
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| Published in: | Breast cancer (Tokyo, Japan) Vol. 29; no. 1; pp. 19 - 29 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
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Singapore
Springer Singapore
2022
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| Abstract | Breast cancer (BC) is the second most common cancer in women, affecting 1 in 8 women in the United States (12.5%) in their lifetime. However, some women have a higher lifetime risk of BC because of genetic and lifestyle factors, mammographic breast density, and reproductive and hormonal factors. Because BC risk is variable, screening and prevention strategies should be individualized after considering patient-specific risk factors. Thus, health care professionals need to be able to assess risk profiles, identify high-risk women, and individualize screening and prevention strategies through a shared decision-making process. In this article, we review the risk factors for BC, risk-assessment models that identify high-risk patients, and preventive medications and lifestyle modifications that may decrease risk. We also discuss the benefits and limitations of various supplemental screening methods. |
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| AbstractList | Breast cancer (BC) is the second most common cancer in women, affecting 1 in 8 women in the United States (12.5%) in their lifetime. However, some women have a higher lifetime risk of BC because of genetic and lifestyle factors, mammographic breast density, and reproductive and hormonal factors. Because BC risk is variable, screening and prevention strategies should be individualized after considering patient-specific risk factors. Thus, health care professionals need to be able to assess risk profiles, identify high-risk women, and individualize screening and prevention strategies through a shared decision-making process. In this article, we review the risk factors for BC, risk-assessment models that identify high-risk patients, and preventive medications and lifestyle modifications that may decrease risk. We also discuss the benefits and limitations of various supplemental screening methods. |
| Audience | Academic |
| Author | Pruthi, Sandhya Bhatt, Asha A. Vegunta, Suneela Choudhery, Sadia A. Kaur, Aparna S. |
| Author_xml | – sequence: 1 givenname: Suneela surname: Vegunta fullname: Vegunta, Suneela email: vegunta.suneela@mayo.edu organization: Division of Women’s Health Internal Medicine, Mayo Clinic – sequence: 2 givenname: Asha A. surname: Bhatt fullname: Bhatt, Asha A. organization: Department of Radiology, Mayo Clinic – sequence: 3 givenname: Sadia A. surname: Choudhery fullname: Choudhery, Sadia A. organization: Department of Radiology, Mayo Clinic – sequence: 4 givenname: Sandhya surname: Pruthi fullname: Pruthi, Sandhya organization: Division of General Internal Medicine, Breast Cancer Clinic, Mayo Clinic – sequence: 5 givenname: Aparna S. surname: Kaur fullname: Kaur, Aparna S. organization: Division of General Internal Medicine, Breast Cancer Clinic, Mayo Clinic |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34665436$$D View this record in MEDLINE/PubMed |
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| Keywords | BRCA Dense breast tissue Breast MRI Risk factors for breast cancer Risk-assessment models |
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| Title | Identifying women with increased risk of breast cancer and implementing risk-reducing strategies and supplemental imaging |
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