Exercise leukocyte profiles in healthy, type 1 diabetic, overweight, and asthmatic children

Leukocytosis contributes to exercise-induced immune modulation, which is a mechanism of cardiovascular protection. However, this process is poorly defined in children. We therefore measured leukocytes in 45 healthy, 18 overweight, 16 type 1 diabetic, and 8 asthmatic children at pre, end-, and 30-min...

Full description

Saved in:

Bibliographic Details
Published in:	Pediatric exercise science Vol. 21; no. 1; p. 19
Main Authors:	Rosa, Jaime S, Schwindt, Christina D, Oliver, Stacy R, Leu, Szu-Yun, Flores, Rebecca L, Galassetti, Pietro R
Format:	Journal Article
Language:	English
Published:	United States 01-02-2009
Subjects:	Adolescent Asthma - blood Case-Control Studies Child Diabetes Mellitus, Type 1 - blood Exercise Test Female Humans Leukocyte Count Male Overweight - blood Physical Exertion - physiology
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Leukocytosis contributes to exercise-induced immune modulation, which is a mechanism of cardiovascular protection. However, this process is poorly defined in children. We therefore measured leukocytes in 45 healthy, 18 overweight, 16 type 1 diabetic, and 8 asthmatic children at pre, end-, and 30-min postexercise (30-min intermittent or 6-min continuous). In all groups, total leukocytes, neutrophils, lymphocytes, and monocytes increased at end-exercise, but returned to baseline by 30-min postexercise, including neutrophils, previously reported to remain elevated for at least some exercise formats. This highly preserved pattern indicates the importance of the adaptive response to physical stress across multiple health conditions.
ISSN:	0899-8493
DOI:	10.1123/pes.21.1.19