D-Galactose as an autoinducer 2 inhibitor to control the biofilm formation of periodontopathogens

Autoinducer 2 (AI-2) is a quorum sensing molecule to which bacteria respond to regulate various phenotypes, including virulence and biofilm formation. AI-2 plays an important role in the formation of a subgingival biofilm composed mostly of Gram-negative anaerobes, by which periodontitis is initiate...

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Bibliographic Details
Published in:	The journal of microbiology Vol. 54; no. 9; pp. 632 - 637
Main Authors:	Ryu, Eun-Ju, Sim, Jaehyun, Sim, Jun, Lee, Julian, Choi, Bong-Kyu
Format:	Journal Article
Language:	English
Published:	Seoul The Microbiological Society of Korea 01-09-2016 Springer Nature B.V 한국미생물학회
Subjects:	Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteroides forsythus Biofilms Biofilms - drug effects Bioluminescence Biomedical and Life Sciences Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism E coli Fusobacterium nucleatum Fusobacterium nucleatum - drug effects Fusobacterium nucleatum - genetics Fusobacterium nucleatum - metabolism Galactose - metabolism Galactose - pharmacology Gram-positive bacteria Gum disease Homoserine - analogs & derivatives Homoserine - antagonists & inhibitors Homoserine - metabolism Humans Lactones - antagonists & inhibitors Lactones - metabolism Life Sciences Microbiology Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - metabolism Periodontitis - microbiology Periplasmic Binding Proteins - genetics Periplasmic Binding Proteins - metabolism Porphyromonas gingivalis Porphyromonas gingivalis - drug effects Porphyromonas gingivalis - physiology Proteins Vibrio - drug effects Vibrio - physiology Vibrio harveyi Virulence 생물학 South Korea AI-2 inhibitor quorum sensing D-galactose periodontopathogens biofilm
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