Quantitative non-invasive cell characterisation and discrimination based on multispectral autofluorescence features

Automated and unbiased methods of non-invasive cell monitoring able to deal with complex biological heterogeneity are fundamentally important for biology and medicine. Label-free cell imaging provides information about endogenous autofluorescent metabolites, enzymes and cofactors in cells. However e...

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Bibliographic Details
Published in:	Scientific reports Vol. 6; no. 1; p. 23453
Main Authors:	Gosnell, Martin E., Anwer, Ayad G., Mahbub, Saabah B., Menon Perinchery, Sandeep, Inglis, David W., Adhikary, Partho P., Jazayeri, Jalal A., Cahill, Michael A., Saad, Sonia, Pollock, Carol A., Sutton-McDowall, Melanie L., Thompson, Jeremy G., Goldys, Ewa M.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 31-03-2016 Nature Publishing Group
Subjects:	631/57 631/57/2267 Animals Blastocyst - metabolism Blastocyst - ultrastructure Cancer CD90 antigen Cell Differentiation Cell Line, Tumor Cell Tracking - instrumentation Cell Tracking - methods Cofactors Diabetes mellitus Diabetes Mellitus, Experimental - genetics Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology Embryos Enzymes Gene Expression Gene Expression Regulation Heterogeneity Humanities and Social Sciences Humans Image processing Image Processing, Computer-Assisted - statistics & numerical data Membrane Proteins - genetics Membrane Proteins - metabolism Metabolites Mice multidisciplinary Mutation Optical Imaging - methods Optical Imaging - statistics & numerical data Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - ultrastructure Receptors, Progesterone - genetics Receptors, Progesterone - metabolism Science Stem cells Stem Cells - cytology Stem Cells - metabolism Subpopulations Thy-1 Antigens - genetics Thy-1 Antigens - metabolism
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